Project measure / variable:   Jentsch2   discrimination1_FR5

ID, description, units MPD:49726   discrimination1_FR5   Fixed ratio 5 - discrimination index between active and inactive levers   [%]  day 1  
cocaine study
Data set, strains Jentsch2   BXD   4 strains     sex: both     age: 8-17wks
Procedure operant conditioning chamber
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  STRAIN COMPARISON PLOT
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Jentsch2 - Fixed ratio 5 - discrimination index between active and inactive levers day 1



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested2 strains4 strains
Mean of the strain means93.4   % 90.4   %
Median of the strain means93.4   % 90.5   %
SD of the strain means± 1.98 ± 4.19
Coefficient of variation (CV)0.0212 0.0463
Min–max range of strain means92.0   –   94.8   % 86.2   –   94.6   %
Mean sample size per strain4.5   mice 7.2   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 6.1532 6.1532 0.182 0.6747
strain 1 13.5673 13.5673 0.4014 0.5343
sex:strain 1 2.3304 2.3304 0.0689 0.7959
Residuals 18 608.4197 33.8011


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
BXD31/TyJ m 87.5 11.2   7 4.25 0.128 66.7, 100.0 -0.7
BXD38/TyJ f 92.0 7.82   7 2.96 0.085 80.8, 100.0 -0.71
BXD38/TyJ m 93.4 5.03   10 1.59 0.0538 87.3, 100.0 0.71
BXD42/TyJ m 86.2 10.6   9 3.55 0.123 62.4, 97.2 -1.01
BXD68/RwwJ f 94.8 0.962   2   0.68 0.0101 94.1, 95.5 0.71
BXD68/RwwJ m 94.6 2.54   3 1.47 0.0268 91.7, 96.1 1.0


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
BXD38/TyJ f 91.98 2.1974 96.5966 87.3634
BXD38/TyJ m 93.397 1.8385 97.2596 89.5344
BXD68/RwwJ f 94.8 4.111 103.4369 86.1631
BXD68/RwwJ m 94.6333 3.3566 101.6854 87.5813


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
BXD38/TyJ both 92.6885 1.4326 95.6982 89.6788
BXD68/RwwJ both 94.7167 2.6537 100.2918 89.1415




GWAS analysis not available: SNP data is not available for enough strains (at least 4)