Project measure / variable:   Jentsch2   infusions2_FR2

ID, description, units MPD:49715   infusions2_FR2   Fixed ratio 2 - self administration: number of infusions earned   [n]  day 2  
cocaine study
Data set, strains Jentsch2   BXD   4 strains     sex: both     age: 8-17wks
Procedure operant conditioning chamber
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  STRAIN COMPARISON PLOT
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Jentsch2 - Fixed ratio 2 - self administration: number of infusions earned day 2



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested2 strains4 strains
Mean of the strain means35.0   n 31.0   n
Median of the strain means35.0   n 33.3   n
SD of the strain means± 5.02 ± 10.3
Coefficient of variation (CV)0.144 0.331
Min–max range of strain means31.4   –   38.5   n 17.4   –   40.0   n
Mean sample size per strain4.5   mice 8.0   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 4.7236 4.7236 0.0755 0.7865
strain 1 413.4681 413.4681 6.6065 0.0187
sex:strain 1 16.3461 16.3461 0.2612 0.6152
Residuals 19 1189.1143 62.585


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
BXD31/TyJ m 17.4 4.28   7 1.62 0.245 11.0, 25.0 -1.33
BXD38/TyJ f 31.4 8.38   7 3.17 0.267 20.0, 40.0 -0.71
BXD38/TyJ m 28.9 7.52   10 2.38 0.26 16.0, 39.0 -0.21
BXD42/TyJ m 37.8 5.58   11 1.68 0.148 28.0, 44.0 0.66
BXD68/RwwJ f 38.5 9.19   2   6.5 0.239 32.0, 45.0 0.71
BXD68/RwwJ m 40.0 7.62   4 3.81 0.19 33.0, 48.0 0.87


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
BXD38/TyJ f 31.4286 2.9901 37.6869 25.1702
BXD38/TyJ m 28.9 2.5017 34.1361 23.6639
BXD68/RwwJ f 38.5 5.594 50.2083 26.7917
BXD68/RwwJ m 40.0 3.9555 48.279 31.721


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
BXD38/TyJ both 30.1643 1.9493 34.2442 26.0843
BXD68/RwwJ both 39.25 3.4256 46.4198 32.0802




GWAS analysis not available: SNP data is not available for enough strains (at least 4)