Project measure / variable:   Jentsch2   discrimination5_FR1

ID, description, units MPD:49708   discrimination5_FR1   Fixed ratio 1 - discrimination index between active and inactive levers   [%]  day 5  
cocaine study
Data set, strains Jentsch2   BXD   4 strains     sex: both     age: 8-17wks
Procedure operant conditioning chamber
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  STRAIN COMPARISON PLOT
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Jentsch2 - Fixed ratio 1 - discrimination index between active and inactive levers day 5



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested2 strains4 strains
Mean of the strain means96.8   % 81.3   %
Median of the strain means96.8   % 82.4   %
SD of the strain means± 2.26 ± 4.55
Coefficient of variation (CV)0.0234 0.0560
Min–max range of strain means95.2   –   98.4   % 74.9   –   85.4   %
Mean sample size per strain4.0   mice 10.5   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 1949.9722 1949.9722 4.4805 0.0458
strain 1 305.6615 305.6615 0.7023 0.411
sex:strain 1 53.5265 53.5265 0.123 0.7291
Residuals 22 9574.6118 435.2096


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
BXD31/TyJ m 81.4 19.4   10 6.14 0.238 38.7, 100.0 0.03
BXD38/TyJ f 95.2 5.81   6 2.37 0.0611 84.6, 100.0 -0.71
BXD38/TyJ m 74.9 25.0   14 6.69 0.334 14.3, 100.0 -1.4
BXD42/TyJ m 83.4 11.9   14 3.18 0.142 58.5, 100.0 0.47
BXD68/RwwJ f 98.4 0.0141   2   0.01 0.000144 98.4, 98.4 0.71
BXD68/RwwJ m 85.4 20.4   4 10.2 0.239 54.8, 97.1 0.91


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
BXD38/TyJ f 95.165 8.5167 112.8276 77.5024
BXD38/TyJ m 74.875 5.5755 86.4379 63.3121
BXD68/RwwJ f 98.4 14.7514 128.9926 67.8074
BXD68/RwwJ m 85.3825 10.4308 107.0147 63.7503


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
BXD38/TyJ both 85.02 5.0897 95.5755 74.4645
BXD68/RwwJ both 91.8913 9.0334 110.6253 73.1572




GWAS analysis not available: SNP data is not available for enough strains (at least 4)