Project measure / variable:   Jentsch2   discrimination3_FR1

ID, description, units MPD:49707   discrimination3_FR1   Fixed ratio 1 - discrimination index between active and inactive levers   [%]  day 3  
cocaine study
Data set, strains Jentsch2   BXD   4 strains     sex: both     age: 8-17wks
Procedure operant conditioning chamber
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  STRAIN COMPARISON PLOT
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Jentsch2 - Fixed ratio 1 - discrimination index between active and inactive levers day 3



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested2 strains4 strains
Mean of the strain means86.0   % 76.8   %
Median of the strain means86.0   % 79.3   %
SD of the strain means± 4.31 ± 7.54
Coefficient of variation (CV)0.0501 0.0982
Min–max range of strain means83.0   –   89.1   % 65.8   –   82.9   %
Mean sample size per strain3.5   mice 10.2   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 1531.8773 1531.8773 2.5145 0.1285
strain 1 424.0256 424.0256 0.696 0.414
sex:strain 1 526.4845 526.4845 0.8642 0.3637
Residuals 20 12184.3276 609.2164


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
BXD31/TyJ m 79.4 23.1   10 7.32 0.292 42.5, 100.0 0.34
BXD38/TyJ f 89.1 15.2   5 6.78 0.17 68.8, 100.0 0.71
BXD38/TyJ m 65.8 28.4   13 7.88 0.432 10.0, 100.0 -1.46
BXD42/TyJ m 79.2 17.1   14 4.58 0.217 42.9, 100.0 0.31
BXD68/RwwJ f 83.0 22.0   2   15.6 0.265 67.4, 98.6 -0.71
BXD68/RwwJ m 82.9 19.0   4 9.52 0.23 55.6, 96.0 0.81


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
BXD38/TyJ f 89.134 11.0383 112.1594 66.1086
BXD38/TyJ m 65.7769 6.8456 80.0567 51.4972
BXD68/RwwJ f 83.005 17.453 119.4114 46.5986
BXD68/RwwJ m 82.9 12.3412 108.6432 57.1568


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
BXD38/TyJ both 77.4555 6.4943 91.0024 63.9085
BXD68/RwwJ both 82.9525 10.6878 105.2468 60.6582




GWAS analysis not available: SNP data is not available for enough strains (at least 4)