Project measure / variable:   Jentsch2   discrimination1_FR1

ID, description, units MPD:49706   discrimination1_FR1   Fixed ratio 1 - discrimination index between active and inactive levers   [%]  day 1  
cocaine study
Data set, strains Jentsch2   BXD   4 strains     sex: both     age: 8-17wks
Procedure operant conditioning chamber
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  STRAIN COMPARISON PLOT
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Jentsch2 - Fixed ratio 1 - discrimination index between active and inactive levers day 1



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested2 strains4 strains
Mean of the strain means93.7   % 52.5   %
Median of the strain means93.7   % 53.0   %
SD of the strain means± 6.72 ± 1.64
Coefficient of variation (CV)0.0717 0.0313
Min–max range of strain means88.9   –   98.4   % 50.1   –   53.8   %
Mean sample size per strain4.0   mice 9.0   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 7899.9481 7899.9481 12.1449 0.0025
strain 1 6.4168 6.4168 0.0099 0.9219
sex:strain 1 157.9474 157.9474 0.2428 0.6278
Residuals 19 12358.9693 650.4721


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
BXD31/TyJ m 52.9 36.1   7 13.6 0.682 7.69, 100.0 0.24
BXD38/TyJ f 88.9 17.2   6 7.03 0.194 66.7, 100.0 -0.71
BXD38/TyJ m 53.2 32.3   11 9.74 0.608 0.43
BXD42/TyJ m 53.8 25.4   14 6.78 0.471 18.8, 100.0 0.79
BXD68/RwwJ f 98.4 2.21   2   1.56 0.0224 96.9, 100.0 0.71
BXD68/RwwJ m 50.1 12.0   4 5.98 0.239 33.3, 60.0 -1.46


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
BXD38/TyJ f 88.89 10.4121 110.6828 67.0972
BXD38/TyJ m 53.1827 7.6899 69.2778 37.0877
BXD68/RwwJ f 98.44 18.0343 136.1862 60.6938
BXD68/RwwJ m 50.1175 12.7522 76.8081 23.4269


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
BXD38/TyJ both 71.0364 6.472 84.5824 57.4904
BXD68/RwwJ both 74.2788 11.0437 97.3935 51.164




GWAS analysis not available: SNP data is not available for enough strains (at least 4)