Project measure / variable:   Jentsch2   infusions_last_FR1

ID, description, units MPD:49705   infusions_last_FR1   Fixed ratio 1 - self administration: number of infusions earned   [n]  last day  
cocaine study
Data set, strains Jentsch2   BXD   4 strains     sex: both     age: 8-17wks
Procedure operant conditioning chamber
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  STRAIN COMPARISON PLOT
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Jentsch2 - Fixed ratio 1 - self administration: number of infusions earned last day



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested2 strains4 strains
Mean of the strain means43.2   n 36.5   n
Median of the strain means43.2   n 34.0   n
SD of the strain means± 16.7 ± 16.5
Coefficient of variation (CV)0.386 0.453
Min–max range of strain means31.4   –   55.0   n 19.9   –   58.2   n
Mean sample size per strain4.5   mice 10.5   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 15.5741 15.5741 0.2658 0.6111
strain 1 3590.5423 3590.5423 61.2678 < 0.0001
sex:strain 1 40.5093 40.5093 0.6912 0.4143
Residuals 23 1347.8929 58.604


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
BXD31/TyJ m 19.9 9.67   10 3.06 0.486 9.0, 37.0 -1.0
BXD38/TyJ f 31.4 3.36   7 1.27 0.107 25.0, 36.0 -0.71
BXD38/TyJ m 28.4 9.21   14 2.46 0.324 15.0, 42.0 -0.49
BXD42/TyJ m 39.6 11.2   14 3.0 0.283 24.0, 65.0 0.19
BXD68/RwwJ f 55.0 4.24   2   3.0 0.0771 52.0, 58.0 0.71
BXD68/RwwJ m 58.2 7.27   4 3.64 0.125 49.0, 65.0 1.31


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
BXD38/TyJ f 31.4286 2.8934 37.4141 25.443
BXD38/TyJ m 28.4286 2.046 32.661 24.1962
BXD68/RwwJ f 55.0 5.4131 66.1979 43.8021
BXD68/RwwJ m 58.25 3.8277 66.1681 50.3319


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
BXD38/TyJ both 29.9286 1.7719 33.594 26.2632
BXD68/RwwJ both 56.625 3.3149 63.4823 49.7677




GWAS analysis not available: SNP data is not available for enough strains (at least 4)