Project measure / variable:   Jentsch2   infusions5_FR1

ID, description, units MPD:49704   infusions5_FR1   Fixed ratio 1 - self administration: number of infusions earned   [n]  day 5  
cocaine study
Data set, strains Jentsch2   BXD   4 strains     sex: both     age: 8-17wks
Procedure operant conditioning chamber
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  STRAIN COMPARISON PLOT
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Jentsch2 - Fixed ratio 1 - self administration: number of infusions earned day 5



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested2 strains4 strains
Mean of the strain means28.7   n 31.4   n
Median of the strain means28.7   n 28.9   n
SD of the strain means± 21.6 ± 18.5
Coefficient of variation (CV)0.754 0.591
Min–max range of strain means13.4   –   44.0   n 15.0   –   52.5   n
Mean sample size per strain4.5   mice 10.5   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 112.6667 112.6667 0.657 0.4259
strain 1 5440.0952 5440.0952 31.7235 < 0.0001
sex:strain 1 29.7619 29.7619 0.1736 0.6808
Residuals 23 3944.1429 171.4845


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
BXD31/TyJ m 15.0 14.6   10 4.61 0.973 3.0, 46.0 -0.88
BXD38/TyJ f 13.4 12.2   7 4.63 0.912 -0.71
BXD38/TyJ m 16.6 13.4   14 3.59 0.812 1.0, 40.0 -0.8
BXD42/TyJ m 41.3 14.6   14 3.91 0.354 19.0, 65.0 0.54
BXD68/RwwJ f 44.0 7.07   2   5.0 0.161 39.0, 49.0 0.71
BXD68/RwwJ m 52.5 14.6   4 7.32 0.279 37.0, 65.0 1.14


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
BXD38/TyJ f 13.4286 4.9495 23.6674 3.1897
BXD38/TyJ m 16.5714 3.4998 23.8114 9.3315
BXD68/RwwJ f 44.0 9.2597 63.1552 24.8448
BXD68/RwwJ m 52.5 6.5476 66.0448 38.9552


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
BXD38/TyJ both 15.0 3.031 21.27 8.73
BXD68/RwwJ both 48.25 5.6704 59.9801 36.5199




GWAS analysis not available: SNP data is not available for enough strains (at least 4)