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Project measure / variable:   Brugnara1   CHCM


  STRAIN COMPARISON PLOT
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Brugnara1 - RBC corpuscular hemoglobin concentration mean (CHCM)



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested10 strains10 strains
Mean of the strain means29.1   g/dL 27.1   g/dL
Median of the strain means29.2   g/dL 27.5   g/dL
SD of the strain means± 1.40 ± 2.66
Coefficient of variation (CV)0.0480 0.0983
Min–max range of strain means26.6   –   31.3   g/dL 22.3   –   30.8   g/dL
Mean sample size per strain32.5   mice 32.5   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 639.0814 639.0814 22.4508 < 0.0001
strain 9 1122.1009 124.6779 4.3799 < 0.0001
sex:strain 9 1461.0388 162.3376 5.7029 < 0.0001
Residuals 631 17961.9356 28.4658


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 29.8 1.71   33 0.298 0.0574 26.8, 31.8 0.51
129S1/SvImJ m 28.3 5.09   35 0.86 0.18 0.45
A/J f 29.8 5.14   37 0.844 0.172 0.51
A/J m 25.6 10.5   36 1.75 0.41 -0.56
BALB/cJ f 30.4 0.883   26 0.173 0.0291 29.6, 32.4 0.94
BALB/cJ m 29.9 0.73   30 0.133 0.0244 28.7, 31.9 1.05
C3H/HeJ f 29.7 5.53   31 0.993 0.186 0.44
C3H/HeJ m 30.8 0.282   30 0.0514 0.00914 30.3, 31.3 1.39
C57BL/6J f 28.3 1.17   35 0.197 0.0412 26.0, 29.9 -0.57
C57BL/6J m 28.2 0.898   33 0.156 0.0318 25.2, 29.5 0.42
C57BLKS/J f 27.5 0.547   32 0.0966 0.0198 26.4, 28.7 -1.14
C57BLKS/J m 26.8 0.94   39 0.15 0.0351 25.6, 29.5 -0.11
CBA/J f 26.6 6.81   34 1.17 0.256 -1.78
CBA/J m 28.9 0.49   34 0.084 0.0169 28.1, 30.4 0.68
DBA/2J f 28.7 0.637   30 0.116 0.0222 26.7, 29.8 -0.28
DBA/2J m 26.2 9.13   29 1.7 0.348 -0.33
NZW/LacJ f 31.3 1.09   32 0.193 0.0349 30.1, 33.8 1.58
NZW/LacJ m 23.9 10.9   30 2.0 0.457 -1.2
SM/J f 28.8 1.36   33 0.236 0.0472 26.1, 30.6 -0.21
SM/J m 22.3 10.9   32 1.92 0.489 -1.8


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f 29.8485 0.9288 31.6723 28.0246
129S1/SvImJ m 28.2629 0.9018 30.0338 26.4919
A/J f 29.8135 0.8771 31.5359 28.0911
A/J m 25.575 0.8892 27.3212 23.8288
BALB/cJ f 30.3692 1.0463 32.424 28.3145
BALB/cJ m 29.9467 0.9741 31.8595 28.0338
C3H/HeJ f 29.6968 0.9583 31.5785 27.815
C3H/HeJ m 30.8 0.9741 32.7129 28.8871
C57BL/6J f 28.3286 0.9018 30.0995 26.5576
C57BL/6J m 28.2121 0.9288 30.036 26.3883
C57BLKS/J f 27.5437 0.9432 29.3959 25.6916
C57BLKS/J m 26.7667 0.8543 28.4444 25.089
CBA/J f 26.5765 0.915 28.3733 24.7797
CBA/J m 28.9324 0.915 30.7292 27.1355
DBA/2J f 28.6933 0.9741 30.6062 26.7805
DBA/2J m 26.2034 0.9907 28.149 24.2579
NZW/LacJ f 31.2687 0.9432 33.1209 29.4166
NZW/LacJ m 23.92 0.9741 25.8329 22.0071
SM/J f 28.7667 0.9288 30.5905 26.9428
SM/J m 22.2625 0.9432 24.1146 20.4104


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ both 29.0557 0.6473 30.3268 27.7846
A/J both 27.6943 0.6245 28.9206 26.4679
BALB/cJ both 30.1579 0.7148 31.5616 28.7543
C3H/HeJ both 30.2484 0.6832 31.59 28.9067
C57BL/6J both 28.2703 0.6473 29.5414 26.9993
C57BLKS/J both 27.1552 0.6363 28.4047 25.9057
CBA/J both 27.7544 0.647 29.025 26.4839
DBA/2J both 27.4484 0.6947 28.8126 26.0842
NZW/LacJ both 27.5944 0.6779 28.9257 26.2631
SM/J both 25.5146 0.6618 26.8143 24.2149




  GWAS USING LINEAR MIXED MODELS