Project measure / variable:   Harrill2   kidney_DB75_ctrl

ID, description, units MPD:44155   kidney_DB75_ctrl   kidney metabolite (DB75) concentration   [µM]  control  
DB289 study
Data set, strains Harrill2   inbred   23 strains     sex: f     age: 6-8wks
Procedure drug and metabolite quantification
Ontology mappings

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  STRAIN COMPARISON PLOT
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Harrill2 - kidney metabolite (DB75) concentration control



  MEASURE SUMMARY
Measure Summary Female
Number of strains tested23 strains
Mean of the strain means1.06   µM
Median of the strain means0.500   µM
SD of the strain means± 2.16
Coefficient of variation (CV)2.03
Min–max range of strain means0   –   10.6   µM
Mean sample size per strain3.1   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
strain 17 464.1076 27.3004 1.3705 0.1934
Residuals 48 956.15 19.9198


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 0.0 0.0   1   0.0 0.0 -0.49
A/J f 0.6 0.548   5 0.245 0.913 -0.21
AKR/J f 0.5 0.707   2   0.5 1.41 -0.26
BTBR T+ Itpr3tf/J f 0.0 0.0   1   0.0 0.0 -0.49
BUB/BnJ f 0.0 0.0   1   0.0 0.0 -0.49
C3H/HeJ f 1.0 0.0   1   0.0 0.0 1.0, 1.0 -0.03
C57BL/6J f 1.6 1.34   5 0.6 0.839 1.0, 4.0 0.25
C57BR/cdJ f 0.0 0.0   4 0.0 0.0 -0.49
C58/J f 1.5 0.707   2   0.5 0.471 1.0, 2.0 0.2
CBA/J f 0.333 0.577   3 0.333 1.73 -0.34
DBA/2J f 0.0 0.0   3 0.0 0.0 -0.49
I/LnJ f 1.0 0.0   2   0.0 0.0 1.0, 1.0 -0.03
KK/HlJ f 1.0 0.816   4 0.408 0.816 -0.03
LG/J f 1.0 0.0   3 0.0 0.0 1.0, 1.0 -0.03
LP/J f 0.333 0.577   3 0.333 1.73 -0.34
MA/MyJ f 0.25 0.5   4 0.25 2.0 -0.38
MRL/MpJ f 0.0 0.0   3 0.0 0.0 -0.49
NON/ShiLtJ f 0.0 0.0   1   0.0 0.0 -0.49
NZW/LacJ f 10.6 15.3   5 6.85 1.45 1.0, 37.0 4.41
PL/J f 1.8 0.447   5 0.2 0.248 1.0, 2.0 0.34
RIIIS/J f 1.2 0.447   5 0.2 0.373 1.0, 2.0 0.06
SEA/GnJ f 0.333 0.577   3 0.333 1.73 -0.34
SM/J f 1.4 0.548   5 0.245 0.391 1.0, 2.0 0.16


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
A/J f 0.6 1.996 4.6132 -3.4132
AKR/J f 0.5 3.1559 6.8454 -5.8454
C57BL/6J f 1.6 1.996 5.6132 -2.4132
C57BR/cdJ f 0.0 2.2316 4.4869 -4.4869
C58/J f 1.5 3.1559 7.8454 -4.8454
CBA/J f 0.3333 2.5768 5.5143 -4.8477
DBA/2J f 0.0 2.5768 5.181 -5.181
I/LnJ f 1.0 3.1559 7.3454 -5.3454
KK/HlJ f 1.0 2.2316 5.4869 -3.4869
LG/J f 1.0 2.5768 6.181 -4.181
LP/J f 0.3333 2.5768 5.5143 -4.8477
MA/MyJ f 0.25 2.2316 4.7369 -4.2369
MRL/MpJ f 0.0 2.5768 5.181 -5.181
NZW/LacJ f 10.6 1.996 14.6132 6.5868
PL/J f 1.8 1.996 5.8132 -2.2132
RIIIS/J f 1.2 1.996 5.2132 -2.8132
SEA/GnJ f 0.3333 2.5768 5.5143 -4.8477
SM/J f 1.4 1.996 5.4132 -2.6132




  GWAS USING LINEAR MIXED MODELS