Project measure / variable:   Chesler2   act_dark_deprivation

ID, description, units MPD:43485   act_dark_deprivation   peak activity time from dark onset, following sleep deprivation   [h]  
Data set, strains Chesler2   CC diallel w/par   57 strains     sex: both     age: 7-15wks
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  STRAIN COMPARISON PLOT
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Chesler2 - peak activity time from dark onset, following sleep deprivation



  8-WAY DIALLEL CROSS VIEW
Female animals
129S ♂ A ♂ B6 ♂ CAST ♂ NOD ♂ NZO ♂ PWK ♂ WSB ♂
129S ♀ — -1.94 -3.98 -5.57 -5.22 -4.56 -1.45 —
A ♀ — — -4.06 4.48 3.78 -5.75 3.90 —
B6 ♀ -4.05 -4.65 — — 4.84 -4.05 -3.48 8.02
CAST ♀ — -5.06 -3.29 -4.77 — -3.80 -4.66 -4.74
NOD ♀ -5.26 -4.36 — — — -3.96 8.05 —
NZO ♀ -2.22 0.710 9.23 — -3.07 — — -4.69
PWK ♀ -3.59 -4.38 — — -4.55 — -3.51 —
WSB ♀ 1.84 -3.29 — — -5.74 -5.00 -4.51 -5.51

Male animals
129S ♂ A ♂ B6 ♂ CAST ♂ NOD ♂ NZO ♂ PWK ♂ WSB ♂
129S ♀ -2.76 4.72 2.72 -6.36 — 3.98 10.5 -3.06
A ♀ — -4.95 -1.38 7.63 -1.61 -3.06 2.60 -3.79
B6 ♀ -4.98 -1.21 -4.45 -4.22 -5.26 10.5 — 7.16
CAST ♀ 2.23 — -4.78 -4.24 3.23 -4.75 -3.39 -1.79
NOD ♀ -5.76 2.61 0.235 5.15 -3.24 -0.893 7.20 —
NZO ♀ 7.83 — -2.53 — — -6.05 — —
PWK ♀ — -5.57 -2.84 — 3.48 — -4.02 —
WSB ♀ — -3.02 -5.10 -5.14 -5.16 -5.32 — -5.65

Cell coloring is based on strain mean Z-scores.     High-end         Mid         Low-end           Mouse over the cells to see additional info.


  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested42 strains48 strains
Mean of the strain means-2.23   h -0.928   h
Median of the strain means-4.01   h -2.93   h
SD of the strain means± 4.13 ± 4.81
Coefficient of variation (CV)-1.85 -5.18
Min–max range of strain means-5.75   –   9.23   h -6.36   –   10.5   h
Mean sample size per strain2.1   mice 2.5   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 46.9837 46.9837 2.3961 0.1258
strain 13 1858.3911 142.9532 7.2904 < 0.0001
sex:strain 13 626.0372 48.1567 2.4559 0.0078
Residuals 75 1470.6249 19.6083


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
Select table page:
Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ m -2.76 0.0   1   0.0 0.0 -2.76, -2.76 -0.38
129SAF1 f -1.94 6.71   3 3.88 -3.46 -5.84, 5.81 0.07
129SAF1 m 4.72 8.52   5 3.81 1.81 -4.86, 11.4 1.18
129SB6F1 f -3.98 2.49   2   1.76 -0.625 -5.74, -2.22 -0.42
129SB6F1 m 2.72 7.29   5 3.26 2.68 -5.25, 9.86 0.76
129SCASTF1 f -5.57 0.0   1   0.0 0.0 -5.57, -5.57 -0.81
129SCASTF1 m -6.36 0.0   1   0.0 0.0 -6.36, -6.36 -1.13
129SNODF1 f -5.22 0.0   1   0.0 0.0 -5.22, -5.22 -0.72
129SNZOF1 f -4.56 0.0   1   0.0 0.0 -4.56, -4.56 -0.56
129SNZOF1 m 3.98 5.06   3 2.92 1.27 -1.76, 7.83 1.02
129SPWKF1 f -1.45 5.36   3 3.09 -3.69 -4.72, 4.73 0.19
129SPWKF1 m 10.5 0.0   1   0.0 0.0 10.5, 10.5 2.38
129SWSBF1 m -3.06 0.0   1   0.0 0.0 -3.06, -3.06 -0.44
AB6F1 f -4.06 0.0   1   0.0 0.0 -4.06, -4.06 -0.44
AB6F1 m -1.38 6.87   2   4.86 -4.98 -6.24, 3.48 -0.09
ACASTF1 f 4.48 1.13   4 0.563 0.251 3.78, 6.14 1.63
ACASTF1 m 7.63 2.82   4 1.41 0.37 5.71, 11.8 1.78
A/J m -4.95 1.02   3 0.587 -0.205 -6.05, -4.05 -0.84
ANODF1 f 3.78 0.0   1   0.0 0.0 3.78, 3.78 1.46
ANODF1 m -1.61 5.22   6 2.13 -3.24 -5.05, 7.15 -0.14
ANZOF1 f -5.75 0.0   1   0.0 0.0 -5.75, -5.75 -0.85
ANZOF1 m -3.06 0.0   1   0.0 0.0 -3.06, -3.06 -0.44
APWKF1 f 3.9 8.2   3 4.73 2.1 -5.26, 10.5 1.49
APWKF1 m 2.6 6.46   4 3.23 2.49 -6.36, 8.46 0.73
AWSBF1 m -3.79 0.0   1   0.0 0.0 -3.79, -3.79 -0.6
B6129SF1/J f -4.05 0.438   2   0.31 -0.108 -4.36, -3.74 -0.44
B6129SF1/J m -4.98 0.866   3 0.5 -0.174 -5.98, -4.48 -0.84
B6AF1/J f -4.65 1.54   2   1.09 -0.332 -5.74, -3.56 -0.58
B6AF1/J m -1.21 7.13   2   5.04 -5.92 -6.25, 3.84 -0.06
B6CASTF1 m -4.22 0.0   1   0.0 0.0 -4.22, -4.22 -0.68
B6NODF1 f 4.84 0.0   1   0.0 0.0 4.84, 4.84 1.71
B6NODF1 m -5.26 0.0   1   0.0 0.0 -5.26, -5.26 -0.9
B6NZOF1 f -4.05 0.41   2   0.29 -0.101 -4.34, -3.76 -0.44
B6NZOF1 m 10.5 0.0   1   0.0 0.0 10.5, 10.5 2.38
B6PWKF1 f -3.48 1.78   2   1.26 -0.512 -4.74, -2.22 -0.3
B6WSBF1 f 8.02 2.38   5 1.06 0.297 5.16, 10.7 2.48
B6WSBF1 m 7.16 0.0   1   0.0 0.0 7.16, 7.16 1.68
C57BL/6J m -4.45 1.21   3 0.7 -0.273 -5.24, -3.05 -0.73
CAST129SF1 m 2.23 3.94   5 1.76 1.77 -4.75, 4.77 0.66
CASTAF1 f -5.06 0.0   1   0.0 0.0 -5.06, -5.06 -0.68
CASTB6F1 f -3.29 0.0   1   0.0 0.0 -3.29, -3.29 -0.26
CASTB6F1 m -4.78 1.5   3 0.866 -0.314 -6.29, -3.29 -0.8
CAST/EiJ f -4.77 1.61   3 0.928 -0.337 -5.94, -2.94 -0.61
CAST/EiJ m -4.24 0.0   2   0.0 0.0 -4.24, -4.24 -0.69
CASTNODF1 m 3.23 3.46   6 1.41 1.07 -3.55, 5.94 0.87
CASTNZOF1 f -3.8 0.622   2   0.44 -0.164 -4.24, -3.36 -0.38
CASTNZOF1 m -4.75 0.0   1   0.0 0.0 -4.75, -4.75 -0.8
CASTPWKF1 f -4.66 1.79   5 0.799 -0.383 -6.05, -1.55 -0.59
CASTPWKF1 m -3.39 3.0   6 1.22 -0.884 -5.55, 2.45 -0.51
CASTWSBF1 f -4.74 0.0   1   0.0 0.0 -4.74, -4.74 -0.61
CASTWSBF1 m -1.79 0.0   1   0.0 0.0 -1.79, -1.79 -0.18
NOD129SF1 f -5.26 0.0   1   0.0 0.0 -5.26, -5.26 -0.73
NOD129SF1 m -5.76 0.0   1   0.0 0.0 -5.76, -5.76 -1.01
NODAF1 f -4.36 0.0   1   0.0 0.0 -4.36, -4.36 -0.51
NODAF1 m 2.61 0.0   1   0.0 0.0 2.61, 2.61 0.74
NODB6F1 m 0.235 4.24   2   2.99 18.0 -2.76, 3.23 0.24
NODCASTF1 m 5.15 0.311   2   0.22 0.0604 4.93, 5.37 1.26
NODNZOF1 f -3.96 0.141   2   0.1 -0.0357 -4.06, -3.86 -0.42
NODNZOF1 m -0.893 8.26   3 4.77 -9.24 -5.75, 8.64 0.01
NODPWKF1 f 8.05 3.03   2   2.14 0.376 5.91, 10.2 2.49
NODPWKF1 m 7.2 3.09   8 1.09 0.43 3.18, 10.7 1.69
NOD/ShiLtJ m -3.24 0.0   1   0.0 0.0 -3.24, -3.24 -0.48
NZO129SF1 f -2.22 0.0   1   0.0 0.0 -2.22, -2.22 0.0
NZO129SF1 m 7.83 0.0   1   0.0 0.0 7.83, 7.83 1.82
NZOAF1 f 0.71 0.0   1   0.0 0.0 0.71, 0.71 0.71
NZOB6F1 f 9.23 1.45   5 0.647 0.157 7.58, 10.6 2.78
NZOB6F1 m -2.53 5.74   8 2.03 -2.26 -5.98, 10.1 -0.33
NZO/HlLtJ m -6.05 0.0   1   0.0 0.0 -6.05, -6.05 -1.07
NZONODF1 f -3.07 0.0   1   0.0 0.0 -3.07, -3.07 -0.2
NZOWSBF1 f -4.69 0.214   3 0.123 -0.0455 -4.94, -4.57 -0.59
PWK129SF1 f -3.59 3.89   2   2.75 -1.08 -6.34, -0.84 -0.33
PWKAF1 f -4.38 0.233   2   0.165 -0.0532 -4.55, -4.22 -0.52
PWKAF1 m -5.57 0.0   1   0.0 0.0 -5.57, -5.57 -0.97
PWKB6F1 m -2.84 0.0   1   0.0 0.0 -2.84, -2.84 -0.4
PWKNODF1 f -4.55 0.0   1   0.0 0.0 -4.55, -4.55 -0.56
PWKNODF1 m 3.48 0.0   1   0.0 0.0 3.48, 3.48 0.92
PWK/PhJ f -3.51 0.645   4 0.323 -0.184 -4.26, -2.76 -0.31
PWK/PhJ m -4.02 2.41   3 1.39 -0.6 -5.55, -1.24 -0.64
WSB129SF1 f 1.84 8.17   2   5.77 4.45 -3.94, 7.61 0.99
WSBAF1 f -3.29 0.0   1   0.0 0.0 -3.29, -3.29 -0.26
WSBAF1 m -3.02 1.1   2   0.775 -0.364 -3.79, -2.24 -0.44
WSBB6F1 m -5.1 0.431   2   0.305 -0.0847 -5.4, -4.79 -0.87
WSBCASTF1 m -5.14 0.727   5 0.325 -0.141 -6.36, -4.56 -0.88
WSB/EiJ f -5.51 0.836   3 0.483 -0.152 -6.05, -4.55 -0.79
WSB/EiJ m -5.65 0.687   3 0.397 -0.122 -6.44, -5.24 -0.98
WSBNODF1 f -5.74 0.0   1   0.0 0.0 -5.74, -5.74 -0.85
WSBNODF1 m -5.16 0.827   2   0.585 -0.16 -5.74, -4.57 -0.88
WSBNZOF1 f -5.0 0.148   5 0.066 -0.0295 -5.07, -4.74 -0.67
WSBNZOF1 m -5.32 0.354   2   0.25 -0.0665 -5.57, -5.07 -0.91
WSBPWKF1 f -4.51 0.689   3 0.398 -0.153 -5.06, -3.74 -0.55


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129SAF1 f -1.94 2.5566 3.153 -7.033
129SAF1 m 4.718 1.9803 8.663 0.773
129SB6F1 f -3.98 3.1312 2.2576 -10.2176
129SB6F1 m 2.718 1.9803 6.663 -1.227
ACASTF1 f 4.4825 2.2141 8.8931 0.0719
ACASTF1 m 7.625 2.2141 12.0356 3.2144
APWKF1 f 3.9033 2.5566 8.9963 -1.1896
APWKF1 m 2.595 2.2141 7.0056 -1.8156
B6129SF1/J f -4.05 3.1312 2.1876 -10.2876
B6129SF1/J m -4.98 2.5566 0.113 -10.073
B6AF1/J f -4.65 3.1312 1.5876 -10.8876
B6AF1/J m -1.205 3.1312 5.0326 -7.4426
CAST/EiJ f -4.7733 2.5566 0.3196 -9.8663
CAST/EiJ m -4.24 3.1312 1.9976 -10.4776
CASTPWKF1 f -4.658 1.9803 -0.713 -8.603
CASTPWKF1 m -3.39 1.8078 0.2113 -6.9913
NODNZOF1 f -3.96 3.1312 2.2776 -10.1976
NODNZOF1 m -0.8933 2.5566 4.1996 -5.9863
NODPWKF1 f 8.05 3.1312 14.2876 1.8124
NODPWKF1 m 7.1963 1.5656 10.315 4.0775
NZOB6F1 f 9.23 1.9803 13.175 5.285
NZOB6F1 m -2.5337 1.5656 0.585 -5.6525
PWK/PhJ f -3.51 2.2141 0.9006 -7.9206
PWK/PhJ m -4.0167 2.5566 1.0763 -9.1096
WSB/EiJ f -5.5133 2.5566 -0.4204 -10.6063
WSB/EiJ m -5.6467 2.5566 -0.5537 -10.7396
WSBNZOF1 f -5.004 1.9803 -1.059 -8.949
WSBNZOF1 m -5.32 3.1312 0.9176 -11.5576


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129SAF1 both 1.389 1.6169 4.6101 -1.8321
129SB6F1 both -0.631 1.8524 3.0592 -4.3212
ACASTF1 both 6.0538 1.5656 9.1725 2.935
APWKF1 both 3.2492 1.691 6.6179 -0.1195
B6129SF1/J both -4.515 2.0212 -0.4887 -8.5413
B6AF1/J both -2.9275 2.2141 1.4831 -7.3381
CAST/EiJ both -4.5067 2.0212 -0.4803 -8.533
CASTPWKF1 both -4.024 1.3407 -1.3532 -6.6948
NODNZOF1 both -2.4267 2.0212 1.5997 -6.453
NODPWKF1 both 7.6231 1.7504 11.11 4.1362
NZOB6F1 both 3.3481 1.2622 5.8626 0.8337
PWK/PhJ both -3.7633 1.691 -0.3946 -7.132
WSB/EiJ both -5.58 1.8078 -1.9787 -9.1813
WSBNZOF1 both -5.162 1.8524 -1.4718 -8.8522




GWAS analysis not available: Strain panel must be either Inbred, HMDP, BXD, BXH, CXB, or AXB/BXA