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Project measure / variable:   Chesler2   creatinine

ID, description, units MPD:43410   creatinine   creatinine (blood)   [mg/dL]  
Data set, strains Chesler2   CC diallel w/par   48 strains     sex: both     age: 7-15wks
Procedure metabolic panel
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  STRAIN COMPARISON PLOT
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Chesler2 - creatinine (blood)



  8-WAY DIALLEL CROSS VIEW
Female animals
129S ♂ A ♂ B6 ♂ CAST ♂ NOD ♂ NZO ♂ PWK ♂ WSB ♂
129S ♀ — 0.200 0.350 0.200 — — 0.200 —
A ♀ — — 0.300 — — 0.300 — —
B6 ♀ 0.200 0.200 0.233 — 0.200 0.200 0.500 —
CAST ♀ — 0.200 0.200 0.200 — 0.300 0.200 0.200
NOD ♀ — 0.200 0.267 — 0.200 0.200 — —
NZO ♀ 0.300 0.200 — — — — — 0.200
PWK ♀ 0.200 0.200 — — 0.200 — — —
WSB ♀ 0.200 0.200 0.200 — 0.200 0.250 0.300 0.200

Male animals
129S ♂ A ♂ B6 ♂ CAST ♂ NOD ♂ NZO ♂ PWK ♂ WSB ♂
129S ♀ — 0.200 0.300 — 0.200 0.250 — —
A ♀ — 0.200 0.275 — 0.250 — 0.200 0.200
B6 ♀ — 0.400 0.224 — 0.300 0.400 — —
CAST ♀ 0.250 0.250 0.200 0.250 0.200 0.300 0.200 —
NOD ♀ — — — — 0.200 0.300 — —
NZO ♀ — — 0.400 — 0.200 0.300 — —
PWK ♀ — 0.200 — — — — 0.200 —
WSB ♀ — 0.200 0.200 0.200 0.250 0.275 — 0.200

Cell coloring is based on strain mean Z-scores.     High-end         Mid         Low-end           Mouse over the cells to see additional info.


  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested35 strains33 strains
Mean of the strain means0.231   mg/dL 0.248   mg/dL
Median of the strain means0.200   mg/dL 0.224   mg/dL
SD of the strain means± 0.0632 ± 0.0617
Coefficient of variation (CV)0.273 0.249
Min–max range of strain means0.200   –   0.500   mg/dL 0.200   –   0.400   mg/dL
Mean sample size per strain1.8   mice 2.2   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 0.0001 0.0001 0.0404 0.8413
strain 7 0.0662 0.0095 4.3169 0.0005
sex:strain 7 0.0181 0.0026 1.1777 0.3256
Residuals 76 0.1664 0.0022


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129SAF1 f 0.2 0.0   1   0.0 0.0 0.2, 0.2 -0.5
129SAF1 m 0.2 0.0   2   0.0 0.0 0.2, 0.2 -0.77
129SB6F1 f 0.35 0.0707   2   0.05 0.202 0.3, 0.4 1.87
129SB6F1 m 0.3 0.0   2   0.0 0.0 0.3, 0.3 0.85
129SCASTF1 f 0.2 0.0   2   0.0 0.0 0.2, 0.2 -0.5
129SNODF1 m 0.2 0.0   2   0.0 0.0 0.2, 0.2 -0.77
129SNZOF1 m 0.25 0.0707   2   0.05 0.283 0.2, 0.3 0.04
129SPWKF1 f 0.2 0.0   1   0.0 0.0 0.2, 0.2 -0.5
AB6F1 f 0.3 0.0   1   0.0 0.0 0.3, 0.3 1.08
AB6F1 m 0.275 0.0957   4 0.0479 0.348 0.2, 0.4 0.44
A/J m 0.2 0.0   4 0.0 0.0 0.2, 0.2 -0.77
ANODF1 m 0.25 0.0837   6 0.0342 0.335 0.2, 0.4 0.04
ANZOF1 f 0.3 0.0   1   0.0 0.0 0.3, 0.3 1.08
APWKF1 m 0.2 0.0   1   0.0 0.0 0.2, 0.2 -0.77
AWSBF1 m 0.2 0.0   1   0.0 0.0 0.2, 0.2 -0.77
B6129SF1/J f 0.2 0.0   2   0.0 0.0 0.2, 0.2 -0.5
B6AF1/J f 0.2 0.0   1   0.0 0.0 0.2, 0.2 -0.5
B6AF1/J m 0.4 0.0   1   0.0 0.0 0.4, 0.4 2.47
B6NODF1 f 0.2 0.0   1   0.0 0.0 0.2, 0.2 -0.5
B6NODF1 m 0.3 0.0   2   0.0 0.0 0.3, 0.3 0.85
B6NZOF1 f 0.2 0.0   1   0.0 0.0 0.2, 0.2 -0.5
B6NZOF1 m 0.4 0.0   1   0.0 0.0 0.4, 0.4 2.47
B6PWKF1 f 0.5 0.0   1   0.0 0.0 0.5, 0.5 4.25
C57BL/6J f 0.233 0.0488   15 0.0126 0.209 0.2, 0.3 0.02
C57BL/6J m 0.224 0.0435   33 0.00758 0.194 0.2, 0.3 -0.38
CAST129SF1 m 0.25 0.0707   2   0.05 0.283 0.2, 0.3 0.04
CASTAF1 f 0.2 0.0   1   0.0 0.0 0.2, 0.2 -0.5
CASTAF1 m 0.25 0.0707   2   0.05 0.283 0.2, 0.3 0.04
CASTB6F1 f 0.2 0.0   1   0.0 0.0 0.2, 0.2 -0.5
CASTB6F1 m 0.2 0.0   3 0.0 0.0 0.2, 0.2 -0.77
CAST/EiJ f 0.2 0.0   5 0.0 0.0 0.2, 0.2 -0.5
CAST/EiJ m 0.25 0.0707   2   0.05 0.283 0.2, 0.3 0.04
CASTNODF1 m 0.2 0.0   1   0.0 0.0 0.2, 0.2 -0.77
CASTNZOF1 f 0.3 0.115   4 0.0577 0.385 0.2, 0.4 1.08
CASTNZOF1 m 0.3 0.0   1   0.0 0.0 0.3, 0.3 0.85
CASTPWKF1 f 0.2 0.0   5 0.0 0.0 0.2, 0.2 -0.5
CASTPWKF1 m 0.2 0.0   5 0.0 0.0 0.2, 0.2 -0.77
CASTWSBF1 f 0.2 0.0   2   0.0 0.0 0.2, 0.2 -0.5
NODAF1 f 0.2 0.0   1   0.0 0.0 0.2, 0.2 -0.5
NODB6F1 f 0.267 0.0577   3 0.0333 0.217 0.2, 0.3 0.56
NODNZOF1 f 0.2 0.0   2   0.0 0.0 0.2, 0.2 -0.5
NODNZOF1 m 0.3 0.0   2   0.0 0.0 0.3, 0.3 0.85
NOD/ShiLtJ f 0.2 0.0   1   0.0 0.0 0.2, 0.2 -0.5
NOD/ShiLtJ m 0.2 0.0   1   0.0 0.0 0.2, 0.2 -0.77
NZO129SF1 f 0.3 0.0   1   0.0 0.0 0.3, 0.3 1.08
NZOAF1 f 0.2 0.0   1   0.0 0.0 0.2, 0.2 -0.5
NZOB6F1 m 0.4 0.0   1   0.0 0.0 0.4, 0.4 2.47
NZO/HlLtJ m 0.3 0.0   1   0.0 0.0 0.3, 0.3 0.85
NZONODF1 m 0.2 0.0   1   0.0 0.0 0.2, 0.2 -0.77
NZOWSBF1 f 0.2 0.0   3 0.0 0.0 0.2, 0.2 -0.5
PWK129SF1 f 0.2 0.0   1   0.0 0.0 0.2, 0.2 -0.5
PWKAF1 f 0.2 0.0   1   0.0 0.0 0.2, 0.2 -0.5
PWKAF1 m 0.2 0.0   1   0.0 0.0 0.2, 0.2 -0.77
PWKNODF1 f 0.2 0.0   1   0.0 0.0 0.2, 0.2 -0.5
PWK/PhJ m 0.2 0.0   2   0.0 0.0 0.2, 0.2 -0.77
WSB129SF1 f 0.2 0.0   1   0.0 0.0 0.2, 0.2 -0.5
WSBAF1 f 0.2 0.0   1   0.0 0.0 0.2, 0.2 -0.5
WSBAF1 m 0.2 0.0   2   0.0 0.0 0.2, 0.2 -0.77
WSBB6F1 f 0.2 0.0   2   0.0 0.0 0.2, 0.2 -0.5
WSBB6F1 m 0.2 0.0   3 0.0 0.0 0.2, 0.2 -0.77
WSBCASTF1 m 0.2 0.0   3 0.0 0.0 0.2, 0.2 -0.77
WSB/EiJ f 0.2 0.0   2   0.0 0.0 0.2, 0.2 -0.5
WSB/EiJ m 0.2 0.0   2   0.0 0.0 0.2, 0.2 -0.77
WSBNODF1 f 0.2 0.0   1   0.0 0.0 0.2, 0.2 -0.5
WSBNODF1 m 0.25 0.0707   2   0.05 0.283 0.2, 0.3 0.04
WSBNZOF1 f 0.25 0.0837   6 0.0342 0.335 0.2, 0.4 0.29
WSBNZOF1 m 0.275 0.0957   4 0.0479 0.348 0.2, 0.4 0.44
WSBPWKF1 f 0.3 0.141   2   0.1 0.471 0.2, 0.4 1.08


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129SB6F1 f 0.35 0.0331 0.4159 0.2841
129SB6F1 m 0.3 0.0331 0.3659 0.2341
C57BL/6J f 0.2333 0.0121 0.2574 0.2093
C57BL/6J m 0.2242 0.0081 0.2405 0.208
CAST/EiJ f 0.2 0.0209 0.2417 0.1583
CAST/EiJ m 0.25 0.0331 0.3159 0.1841
CASTPWKF1 f 0.2 0.0209 0.2417 0.1583
CASTPWKF1 m 0.2 0.0209 0.2417 0.1583
NODNZOF1 f 0.2 0.0331 0.2659 0.1341
NODNZOF1 m 0.3 0.0331 0.3659 0.2341
WSBB6F1 f 0.2 0.0331 0.2659 0.1341
WSBB6F1 m 0.2 0.027 0.2538 0.1462
WSB/EiJ f 0.2 0.0331 0.2659 0.1341
WSB/EiJ m 0.2 0.0331 0.2659 0.1341
WSBNZOF1 f 0.25 0.0191 0.2881 0.2119
WSBNZOF1 m 0.275 0.0234 0.3216 0.2284


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129SB6F1 both 0.325 0.0234 0.3716 0.2784
C57BL/6J both 0.2288 0.0073 0.2433 0.2143
CAST/EiJ both 0.225 0.0196 0.264 0.186
CASTPWKF1 both 0.2 0.0148 0.2295 0.1705
NODNZOF1 both 0.25 0.0234 0.2966 0.2034
WSBB6F1 both 0.2 0.0214 0.2425 0.1575
WSB/EiJ both 0.2 0.0234 0.2466 0.1534
WSBNZOF1 both 0.2625 0.0151 0.2926 0.2324




GWAS analysis not available: Strain panel must be either Inbred, HMDP, BXD, BXH, CXB, or AXB/BXA