Project measure / variable:   Johnson4   ABR_click

ID, description, units MPD:42601   ABR_click   auditory brainstem response (ABR) threshold, sound pressure level   [dB]  click stimulus  
Data set, strains Johnson4   B6.PWD consomic w/par   28 strains     sex: both     age: 49-63wks
Procedure ABR test
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  STRAIN COMPARISON PLOT
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Johnson4 - auditory brainstem response (ABR) threshold, sound pressure level click stimulus



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested28 strains28 strains
Mean of the strain means78.6   dB 68.5   dB
Median of the strain means81.9   dB 67.3   dB
SD of the strain means± 12.2 ± 12.9
Coefficient of variation (CV)0.156 0.188
Min–max range of strain means45.9   –   95.0   dB 41.4   –   90.6   dB
Mean sample size per strain8.4   mice 8.0   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 10286.8245 10286.8245 69.4527 < 0.0001
strain 27 67327.1146 2493.5968 16.8358 < 0.0001
sex:strain 27 5053.6929 187.1738 1.2637 0.1733
Residuals 400 59245.0325 148.1126


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
B6.PWD-Chr1 f 75.8 12.8   6 5.23 0.169 60.0, 90.0 -0.23
B6.PWD-Chr1 m 67.2 10.3   9 3.45 0.154 50.0, 85.0 -0.1
B6.PWD-Chr10.1 f 70.0 14.9   10 4.71 0.213 50.0, 90.0 -0.71
B6.PWD-Chr10.1 m 53.1 11.3   8 4.0 0.213 40.0, 70.0 -1.2
B6.PWD-Chr10.2 f 48.9 6.01   9 2.0 0.123 40.0, 60.0 -2.43
B6.PWD-Chr10.2 m 45.0 6.61   9 2.2 0.147 40.0, 60.0 -1.82
B6.PWD-Chr10.3 f 81.1 15.0   9 4.98 0.184 55.0, 100.0 0.2
B6.PWD-Chr10.3 m 65.7 9.32   7 3.52 0.142 50.0, 80.0 -0.22
B6.PWD-Chr11.1 f 80.0 14.4   8 5.09 0.18 55.0, 95.0 0.11
B6.PWD-Chr11.1 m 80.0 13.1   8 4.63 0.164 60.0, 95.0 0.89
B6.PWD-Chr11.2 f 76.0 15.6   5 6.96 0.205 50.0, 90.0 -0.22
B6.PWD-Chr11.2 m 79.4 11.6   9 3.86 0.146 65.0, 95.0 0.84
B6.PWD-Chr11.3 f 90.8 8.01   6 3.27 0.0882 75.0, 95.0 0.99
B6.PWD-Chr11.3 m 83.5 14.2   10 4.48 0.169 55.0, 100.0 1.16
B6.PWD-Chr12 f 87.9 12.5   7 4.74 0.143 65.0, 100.0 0.76
B6.PWD-Chr12 m 75.6 11.0   9 3.67 0.146 60.0, 95.0 0.55
B6.PWD-Chr13 f 89.2 6.65   6 2.71 0.0745 80.0, 100.0 0.86
B6.PWD-Chr13 m 82.5 14.4   8 5.09 0.174 50.0, 95.0 1.08
B6.PWD-Chr14 f 93.5 5.3   10 1.67 0.0566 80.0, 100.0 1.21
B6.PWD-Chr14 m 79.3 13.4   7 5.05 0.169 60.0, 100.0 0.84
B6.PWD-Chr15 f 83.9 10.2   9 3.41 0.122 70.0, 100.0 0.43
B6.PWD-Chr15 m 65.0 15.8   8 5.59 0.243 45.0, 95.0 -0.27
B6.PWD-Chr16 f 95.0 6.24   10 1.97 0.0656 85.0, 100.0 1.34
B6.PWD-Chr16 m 86.9 8.84   8 3.12 0.102 75.0, 100.0 1.43
B6.PWD-Chr17 f 77.1 15.0   7 5.65 0.194 55.0, 90.0 -0.13
B6.PWD-Chr17 m 59.3 11.3   7 4.29 0.191 45.0, 75.0 -0.71
B6.PWD-Chr18 f 60.0 12.5   8 4.43 0.209 45.0, 85.0 -1.52
B6.PWD-Chr18 m 48.6 6.27   7 2.37 0.129 40.0, 55.0 -1.54
B6.PWD-Chr19 f 86.2 18.5   8 6.53 0.214 50.0, 100.0 0.62
B6.PWD-Chr19 m 61.7 15.4   9 5.14 0.25 45.0, 90.0 -0.53
B6.PWD-Chr2 f 90.0 7.64   7 2.89 0.0849 80.0, 100.0 0.93
B6.PWD-Chr2 m 89.2 12.0   6 4.9 0.135 70.0, 100.0 1.6
B6.PWD-Chr3 f 64.4 19.2   8 6.78 0.298 40.0, 95.0 -1.16
B6.PWD-Chr3 m 61.4 14.1   7 5.31 0.229 40.0, 85.0 -0.55
B6.PWD-Chr5 f 88.5 12.0   10 3.8 0.136 65.0, 100.0 0.8
B6.PWD-Chr5 m 90.6 11.2   8 3.95 0.123 70.0, 100.0 1.71
B6.PWD-Chr6 f 81.7 11.5   9 3.82 0.14 65.0, 95.0 0.25
B6.PWD-Chr6 m 63.1 16.5   8 5.82 0.261 45.0, 90.0 -0.42
B6.PWD-Chr8 f 66.0 10.7   10 3.4 0.163 50.0, 90.0 -1.03
B6.PWD-Chr8 m 57.5 15.0   10 4.73 0.26 40.0, 90.0 -0.85
B6.PWD-Chr9 f 82.5 11.4   10 3.59 0.138 65.0, 95.0 0.31
B6.PWD-Chr9 m 70.6 12.9   8 4.57 0.183 50.0, 90.0 0.16
B6.PWD-ChrX.1 f 83.1 14.1   8 4.99 0.17 50.0, 95.0 0.36
B6.PWD-ChrX.1 m 75.0 13.9   8 4.91 0.185 55.0, 95.0 0.5
B6.PWD-ChrX.2 f 84.1 10.7   11 3.22 0.127 70.0, 100.0 0.45
B6.PWD-ChrX.2 m 67.5 10.9   10 3.44 0.161 50.0, 85.0 -0.08
B6.PWD-ChrX.3 f 79.5 14.4   10 4.56 0.181 45.0, 90.0 0.07
B6.PWD-ChrX.3 m 67.9 19.3   7 7.31 0.285 40.0, 90.0 -0.05
B6.PWD-ChrY f 82.1 15.0   7 5.65 0.182 60.0, 100.0 0.28
B6.PWD-ChrY m 67.1 6.99   7 2.64 0.104 55.0, 75.0 -0.11
B6.PWD-mt f 84.4 6.78   8 2.4 0.0804 75.0, 90.0 0.47
B6.PWD-mt m 73.1 7.53   8 2.66 0.103 65.0, 85.0 0.36
C57BL/6J f 74.4 15.9   8 5.62 0.214 45.0, 100.0 -0.35
C57BL/6J m 61.2 4.79   4 2.39 0.0782 55.0, 65.0 -0.57
PWD/PhJ f 45.9 3.02   11 0.909 0.0657 40.0, 50.0 -2.67
PWD/PhJ m 41.4 3.78   7 1.43 0.0912 35.0, 45.0 -2.1


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
B6.PWD-Chr1 f 75.8333 4.9684 85.6009 66.0658
B6.PWD-Chr1 m 67.2222 4.0567 75.1974 59.2471
B6.PWD-Chr10.1 f 70.0 3.8485 77.5659 62.4341
B6.PWD-Chr10.1 m 53.125 4.3028 61.5839 44.6661
B6.PWD-Chr10.2 f 48.8889 4.0567 56.864 40.9137
B6.PWD-Chr10.2 m 45.0 4.0567 52.9752 37.0248
B6.PWD-Chr10.3 f 81.1111 4.0567 89.0863 73.136
B6.PWD-Chr10.3 m 65.7143 4.5999 74.7573 56.6713
B6.PWD-Chr11.1 f 80.0 4.3028 88.4589 71.5411
B6.PWD-Chr11.1 m 80.0 4.3028 88.4589 71.5411
B6.PWD-Chr11.2 f 76.0 5.4427 86.6998 65.3002
B6.PWD-Chr11.2 m 79.4444 4.0567 87.4196 71.4693
B6.PWD-Chr11.3 f 90.8333 4.9684 100.6009 81.0658
B6.PWD-Chr11.3 m 83.5 3.8485 91.0659 75.9341
B6.PWD-Chr12 f 87.8571 4.5999 96.9001 78.8142
B6.PWD-Chr12 m 75.5556 4.0567 83.5307 67.5804
B6.PWD-Chr13 f 89.1667 4.9684 98.9342 79.3991
B6.PWD-Chr13 m 82.5 4.3028 90.9589 74.0411
B6.PWD-Chr14 f 93.5 3.8485 101.0659 85.9341
B6.PWD-Chr14 m 79.2857 4.5999 88.3287 70.2427
B6.PWD-Chr15 f 83.8889 4.0567 91.864 75.9137
B6.PWD-Chr15 m 65.0 4.3028 73.4589 56.5411
B6.PWD-Chr16 f 95.0 3.8485 102.5659 87.4341
B6.PWD-Chr16 m 86.875 4.3028 95.3339 78.4161
B6.PWD-Chr17 f 77.1429 4.5999 86.1858 68.0999
B6.PWD-Chr17 m 59.2857 4.5999 68.3287 50.2427
B6.PWD-Chr18 f 60.0 4.3028 68.4589 51.5411
B6.PWD-Chr18 m 48.5714 4.5999 57.6144 39.5285
B6.PWD-Chr19 f 86.25 4.3028 94.7089 77.7911
B6.PWD-Chr19 m 61.6667 4.0567 69.6418 53.6915
B6.PWD-Chr2 f 90.0 4.5999 99.043 80.957
B6.PWD-Chr2 m 89.1667 4.9684 98.9342 79.3991
B6.PWD-Chr3 f 64.375 4.3028 72.8339 55.9161
B6.PWD-Chr3 m 61.4286 4.5999 70.4715 52.3856
B6.PWD-Chr5 f 88.5 3.8485 96.0659 80.9341
B6.PWD-Chr5 m 90.625 4.3028 99.0839 82.1661
B6.PWD-Chr6 f 81.6667 4.0567 89.6418 73.6915
B6.PWD-Chr6 m 63.125 4.3028 71.5839 54.6661
B6.PWD-Chr8 f 66.0 3.8485 73.5659 58.4341
B6.PWD-Chr8 m 57.5 3.8485 65.0659 49.9341
B6.PWD-Chr9 f 82.5 3.8485 90.0659 74.9341
B6.PWD-Chr9 m 70.625 4.3028 79.0839 62.1661
B6.PWD-ChrX.1 f 83.125 4.3028 91.5839 74.6661
B6.PWD-ChrX.1 m 75.0 4.3028 83.4589 66.5411
B6.PWD-ChrX.2 f 84.0909 3.6694 91.3047 76.8771
B6.PWD-ChrX.2 m 67.5 3.8485 75.0659 59.9341
B6.PWD-ChrX.3 f 79.5 3.8485 87.0659 71.9341
B6.PWD-ChrX.3 m 67.8571 4.5999 76.9001 58.8142
B6.PWD-ChrY f 82.1429 4.5999 91.1858 73.0999
B6.PWD-ChrY m 67.1429 4.5999 76.1858 58.0999
B6.PWD-mt f 84.375 4.3028 92.8339 75.9161
B6.PWD-mt m 73.125 4.3028 81.5839 64.6661
C57BL/6J f 74.375 4.3028 82.8339 65.9161
C57BL/6J m 61.25 6.0851 73.2127 49.2873
PWD/PhJ f 45.9091 3.6694 53.1229 38.6953
PWD/PhJ m 41.4286 4.5999 50.4715 32.3856


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
B6.PWD-Chr1 both 71.5278 3.2071 77.8327 65.2229
B6.PWD-Chr10.1 both 61.5625 2.8864 67.2369 55.8881
B6.PWD-Chr10.2 both 46.9444 2.8685 52.5837 41.3052
B6.PWD-Chr10.3 both 73.4127 3.0666 79.4413 67.3841
B6.PWD-Chr11.1 both 80.0 3.0425 85.9814 74.0186
B6.PWD-Chr11.2 both 77.7222 3.3941 84.3947 71.0497
B6.PWD-Chr11.3 both 87.1667 3.1423 93.3442 80.9891
B6.PWD-Chr12 both 81.7063 3.0666 87.735 75.6777
B6.PWD-Chr13 both 85.8333 3.2863 92.2939 79.3727
B6.PWD-Chr14 both 86.3929 2.9988 92.2882 80.4976
B6.PWD-Chr15 both 74.4444 2.9568 80.2573 68.6316
B6.PWD-Chr16 both 90.9375 2.8864 96.6119 85.2631
B6.PWD-Chr17 both 68.2143 3.2526 74.6086 61.8199
B6.PWD-Chr18 both 54.2857 3.1493 60.477 48.0944
B6.PWD-Chr19 both 73.9583 2.9568 79.7712 68.1455
B6.PWD-Chr2 both 89.5833 3.3854 96.2388 82.9279
B6.PWD-Chr3 both 62.9018 3.1493 69.0931 56.7105
B6.PWD-Chr5 both 89.5625 2.8864 95.2369 83.8881
B6.PWD-Chr6 both 72.3958 2.9568 78.2087 66.583
B6.PWD-Chr8 both 61.75 2.7213 67.0999 56.4001
B6.PWD-Chr9 both 76.5625 2.8864 82.2369 70.8881
B6.PWD-ChrX.1 both 79.0625 3.0425 85.0439 73.0811
B6.PWD-ChrX.2 both 75.7955 2.6588 81.0223 70.5686
B6.PWD-ChrX.3 both 73.6786 2.9988 79.5739 67.7833
B6.PWD-ChrY both 74.6429 3.2526 81.0372 68.2485
B6.PWD-mt both 78.75 3.0425 84.7314 72.7686
C57BL/6J both 67.8125 3.7263 75.1381 60.4869
PWD/PhJ both 43.6688 2.9421 49.4527 37.8849




GWAS analysis not available: Strain panel must be either Inbred, HMDP, BXD, BXH, CXB, or AXB/BXA