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Project measure / variable:   Johnson3   ABR_32kHz

ID, description, units MPD:42504   ABR_32kHz   auditory brainstem response (ABR) threshold, sound pressure level   [dB]  32 kHz tone stimulus  
Data set, strains Johnson3   B6.A consomic w/par   24 strains     sex: both     age: 23-30wks
Procedure ABR test
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  STRAIN COMPARISON PLOT
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Johnson3 - auditory brainstem response (ABR) threshold, sound pressure level 32 kHz tone stimulus



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested23 strains24 strains
Mean of the strain means50.9   dB 48.7   dB
Median of the strain means46.7   dB 45.6   dB
SD of the strain means± 12.9 ± 12.4
Coefficient of variation (CV)0.254 0.254
Min–max range of strain means40.0   –   95.0   dB 40.0   –   100   dB
Mean sample size per strain7.1   mice 7.7   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 426.3697 426.3697 5.869 0.016
strain 22 47558.3648 2161.7439 29.7567 < 0.0001
sex:strain 22 2782.357 126.4708 1.7409 0.0223
Residuals 302 21939.5177 72.6474


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
A/J f 95.0 10.0   4 5.0 0.105 80.0, 100.0 3.41
A/J m 100.0 0.0   5 0.0 0.0 100.0, 100.0 4.14
B6.A-Chr1 f 48.3 7.53   6 3.07 0.156 40.0, 60.0 -0.2
B6.A-Chr1 m 47.1 7.56   7 2.86 0.16 40.0, 60.0 -0.13
B6.A-Chr10 f 81.0 12.6   15 3.24 0.155 50.0, 95.0 2.33
B6.A-Chr10 m 66.1 15.3   19 3.52 0.232 50.0, 100.0 1.4
B6.A-Chr11 f 60.3 13.9   15 3.6 0.231 40.0, 90.0 0.73
B6.A-Chr11 m 59.7 12.2   16 3.04 0.204 50.0, 90.0 0.89
B6.A-Chr12 f 41.9 3.72   8 1.32 0.0888 40.0, 50.0 -0.7
B6.A-Chr12 m 44.4 7.29   8 2.58 0.164 40.0, 60.0 -0.35
B6.A-Chr13 f 55.0 7.07   2   5.0 0.129 50.0, 60.0 0.31
B6.A-Chr13 m 40.0 0.0   3 0.0 0.0 40.0, 40.0 -0.71
B6.A-Chr14 f 50.0 0.0   3 0.0 0.0 50.0, 50.0 -0.07
B6.A-Chr14 m 43.6 4.76   7 1.8 0.109 40.0, 50.0 -0.42
B6.A-Chr15 f 48.3 7.53   6 3.07 0.156 40.0, 60.0 -0.2
B6.A-Chr15 m 46.2 5.18   8 1.83 0.112 40.0, 50.0 -0.21
B6.A-Chr16 f 46.7 5.0   9 1.67 0.107 40.0, 50.0 -0.33
B6.A-Chr16 m 42.5 5.0   4 2.5 0.118 40.0, 50.0 -0.51
B6.A-Chr17 f 57.5 4.18   6 1.71 0.0728 50.0, 60.0 0.51
B6.A-Chr17 m 48.2 6.68   14 1.79 0.139 40.0, 65.0 -0.04
B6.A-Chr18 f 46.2 6.94   8 2.45 0.15 40.0, 60.0 -0.37
B6.A-Chr18 m 46.2 4.79   4 2.39 0.104 40.0, 50.0 -0.21
B6.A-Chr19 f 45.0 5.77   4 2.89 0.128 40.0, 50.0 -0.46
B6.A-Chr19 m 50.8 6.65   6 2.71 0.131 40.0, 60.0 0.17
B6.A-Chr2 f 43.6 4.76   7 1.8 0.109 40.0, 50.0 -0.57
B6.A-Chr2 m 42.1 3.93   7 1.49 0.0933 40.0, 50.0 -0.54
B6.A-Chr3 f 52.3 15.9   13 4.41 0.304 40.0, 90.0 0.11
B6.A-Chr3 m 43.1 4.58   8 1.62 0.106 40.0, 50.0 -0.46
B6.A-Chr4 f 46.0 5.48   5 2.45 0.119 40.0, 50.0 -0.38
B6.A-Chr4 m 40.8 2.04   6 0.833 0.05 40.0, 45.0 -0.64
B6.A-Chr5 f 40.0 0.0   2   0.0 0.0 40.0, 40.0 -0.85
B6.A-Chr5 m 50.0 0.0   5 0.0 0.0 50.0, 50.0 0.1
B6.A-Chr6 f 48.3 2.58   6 1.05 0.0534 45.0, 50.0 -0.2
B6.A-Chr6 m 46.2 6.29   4 3.15 0.136 40.0, 55.0 -0.21
B6.A-Chr7 f 45.0 5.27   10 1.67 0.117 40.0, 50.0 -0.46
B6.A-Chr7 m 43.8 5.18   8 1.83 0.118 40.0, 50.0 -0.4
B6.A-Chr8 f 45.0 5.0   3 2.89 0.111 40.0, 50.0 -0.46
B6.A-Chr8 m 42.7 4.67   11 1.41 0.109 40.0, 50.0 -0.49
B6.A-Chr9 f 46.7 6.61   9 2.2 0.142 40.0, 60.0 -0.33
B6.A-Chr9 m 46.5 8.18   10 2.59 0.176 40.0, 60.0 -0.18
B6.A-ChrX f 42.0 3.5   10 1.11 0.0832 40.0, 50.0 -0.69
B6.A-ChrX m 41.9 3.72   8 1.32 0.0888 40.0, 50.0 -0.55
B6.A-ChrY f 40.0 0.0   5 0.0 0.0 40.0, 40.0 -0.85
B6.A-ChrY m 45.0 5.77   4 2.89 0.128 40.0, 50.0 -0.3
B6.A-mt m 48.0 4.83   10 1.53 0.101 40.0, 55.0 -0.06
C57BL/6J f 47.3 9.58   11 2.89 0.203 40.0, 65.0 -0.28
C57BL/6J m 45.0 5.59   9 1.86 0.124 40.0, 55.0 -0.3


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
A/J f 95.0 4.2617 103.3863 86.6137
A/J m 100.0 3.8118 107.501 92.499
B6.A-Chr1 f 48.3333 3.4796 55.1807 41.4859
B6.A-Chr1 m 47.1429 3.2215 53.4823 40.8034
B6.A-Chr10 f 81.0 2.2007 85.3307 76.6693
B6.A-Chr10 m 66.0526 1.9554 69.9005 62.2047
B6.A-Chr11 f 60.3333 2.2007 64.664 56.0026
B6.A-Chr11 m 59.6875 2.1308 63.8807 55.4943
B6.A-Chr12 f 41.875 3.0135 47.805 35.945
B6.A-Chr12 m 44.375 3.0135 50.305 38.445
B6.A-Chr13 f 55.0 6.0269 66.8601 43.1399
B6.A-Chr13 m 40.0 4.921 49.6837 30.3163
B6.A-Chr14 f 50.0 4.921 59.6837 40.3163
B6.A-Chr14 m 43.5714 3.2215 49.9109 37.232
B6.A-Chr15 f 48.3333 3.4796 55.1807 41.4859
B6.A-Chr15 m 46.25 3.0135 52.18 40.32
B6.A-Chr16 f 46.6667 2.8411 52.2576 41.0758
B6.A-Chr16 m 42.5 4.2617 50.8863 34.1137
B6.A-Chr17 f 57.5 3.4796 64.3474 50.6526
B6.A-Chr17 m 48.2143 2.278 52.697 43.7316
B6.A-Chr18 f 46.25 3.0135 52.18 40.32
B6.A-Chr18 m 46.25 4.2617 54.6363 37.8637
B6.A-Chr19 f 45.0 4.2617 53.3863 36.6137
B6.A-Chr19 m 50.8333 3.4796 57.6807 43.9859
B6.A-Chr2 f 43.5714 3.2215 49.9109 37.232
B6.A-Chr2 m 42.1429 3.2215 48.4823 35.8034
B6.A-Chr3 f 52.3077 2.364 56.9596 47.6558
B6.A-Chr3 m 43.125 3.0135 49.055 37.195
B6.A-Chr4 f 46.0 3.8118 53.501 38.499
B6.A-Chr4 m 40.8333 3.4796 47.6807 33.9859
B6.A-Chr5 f 40.0 6.0269 51.8601 28.1399
B6.A-Chr5 m 50.0 3.8118 57.501 42.499
B6.A-Chr6 f 48.3333 3.4796 55.1807 41.4859
B6.A-Chr6 m 46.25 4.2617 54.6363 37.8637
B6.A-Chr7 f 45.0 2.6953 50.304 39.696
B6.A-Chr7 m 43.75 3.0135 49.68 37.82
B6.A-Chr8 f 45.0 4.921 54.6837 35.3163
B6.A-Chr8 m 42.7273 2.5699 47.7844 37.6701
B6.A-Chr9 f 46.6667 2.8411 52.2576 41.0758
B6.A-Chr9 m 46.5 2.6953 51.804 41.196
B6.A-ChrX f 42.0 2.6953 47.304 36.696
B6.A-ChrX m 41.875 3.0135 47.805 35.945
B6.A-ChrY f 40.0 3.8118 47.501 32.499
B6.A-ChrY m 45.0 4.2617 53.3863 36.6137
C57BL/6J f 47.2727 2.5699 52.3299 42.2156
C57BL/6J m 45.0 2.8411 50.5909 39.4091


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
A/J both 97.5 2.8588 103.1257 91.8743
B6.A-Chr1 both 47.7381 2.371 52.4038 43.0724
B6.A-Chr10 both 73.5263 1.472 76.4229 70.6297
B6.A-Chr11 both 60.0104 1.5316 63.0244 56.9964
B6.A-Chr12 both 43.125 2.1308 47.3182 38.9318
B6.A-Chr13 both 47.5 3.8904 55.1556 39.8444
B6.A-Chr14 both 46.7857 2.9408 52.5728 40.9986
B6.A-Chr15 both 47.2917 2.3016 51.8208 42.7625
B6.A-Chr16 both 44.5833 2.5609 49.6229 39.5438
B6.A-Chr17 both 52.8571 2.0795 56.9493 48.765
B6.A-Chr18 both 46.25 2.6097 51.3856 41.1144
B6.A-Chr19 both 47.9167 2.7509 53.33 42.5033
B6.A-Chr2 both 42.8571 2.278 47.3398 38.3745
B6.A-Chr3 both 47.7163 1.915 51.4848 43.9479
B6.A-Chr4 both 43.4167 2.5806 48.4948 38.3385
B6.A-Chr5 both 45.0 3.5656 52.0165 37.9835
B6.A-Chr6 both 47.2917 2.7509 52.705 41.8783
B6.A-Chr7 both 44.375 2.0215 48.353 40.397
B6.A-Chr8 both 43.8636 2.7758 49.326 38.4013
B6.A-Chr9 both 46.5833 1.9581 50.4366 42.7301
B6.A-ChrX both 41.9375 2.0215 45.9155 37.9595
B6.A-ChrY both 42.5 2.8588 48.1257 36.8743
C57BL/6J both 46.1364 1.9155 49.9057 42.367




GWAS analysis not available: Strain panel must be either Inbred, HMDP, BXD, BXH, CXB, or AXB/BXA