Project measure / variable:   Donahue9   chloride

ID, description, units MPD:41803   chloride   chloride (serum Cl)   [mmol/L]  
Data set, strains Donahue9   B6.PWD consomic w/par   24 strains     sex: both     age: 11wks
Procedure metabolic panel
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  STRAIN COMPARISON PLOT
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Donahue9 - chloride (serum Cl)



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested22 strains24 strains
Mean of the strain means114   mmol/L 113   mmol/L
Median of the strain means116   mmol/L 114   mmol/L
SD of the strain means± 7.18 ± 7.32
Coefficient of variation (CV)0.0630 0.0649
Min–max range of strain means100   –   125   mmol/L 101   –   124   mmol/L
Mean sample size per strain5.7   mice 6.6   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 7.4413 7.4413 0.4697 0.4938
strain 21 11584.4744 551.6416 34.8214 < 0.0001
sex:strain 21 693.9818 33.0468 2.086 0.0046
Residuals 229 3627.8201 15.842


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
B6.PWD-Chr1 f 115.0 7.59   8 2.68 0.0662 104.0, 124.0 0.14
B6.PWD-Chr1 m 114.0 5.7   8 2.01 0.0502 107.0, 123.0 0.15
B6.PWD-Chr10.1 f 120.0 2.92   4 1.46 0.0244 118.0, 124.0 0.84
B6.PWD-Chr10.1 m 123.0 2.51   8 0.888 0.0204 119.0, 128.0 1.38
B6.PWD-Chr10.2 f 125.0 2.61   5 1.17 0.0209 123.0, 129.0 1.53
B6.PWD-Chr10.2 m 124.0 2.83   10 0.895 0.0228 120.0, 129.0 1.52
B6.PWD-Chr10.3 f 122.0 1.95   6 0.796 0.016 119.0, 124.0 1.11
B6.PWD-Chr10.3 m 114.0 1.14   6 0.467 0.01 113.0, 116.0 0.15
B6.PWD-Chr11.1 f 119.0 1.42   7 0.538 0.012 117.0, 121.0 0.7
B6.PWD-Chr11.1 m 120.0 2.43   12 0.702 0.0203 116.0, 124.0 0.97
B6.PWD-Chr11.2 f 114.0 7.36   8 2.6 0.0647 97.2, 120.0 0.0
B6.PWD-Chr11.2 m 118.0 3.12   9 1.04 0.0265 113.0, 122.0 0.7
B6.PWD-Chr11.3 f 122.0 3.6   10 1.14 0.0296 118.0, 127.0 1.11
B6.PWD-Chr11.3 m 121.0 2.37   8 0.839 0.0196 118.0, 125.0 1.11
B6.PWD-Chr12 f 119.0 1.98   2   1.4 0.0166 118.0, 121.0 0.7
B6.PWD-Chr12 m 114.0 5.34   6 2.18 0.0467 107.0, 121.0 0.15
B6.PWD-Chr14 f 121.0 4.2   7 1.59 0.0346 117.0, 130.0 0.97
B6.PWD-Chr14 m 121.0 3.55   7 1.34 0.0293 115.0, 124.0 1.11
B6.PWD-Chr15 f 114.0 2.63   5 1.18 0.023 112.0, 118.0 0.0
B6.PWD-Chr15 m 114.0 0.529   3 0.306 0.00464 113.0, 114.0 0.15
B6.PWD-Chr16 f 114.0 1.26   6 0.515 0.0111 112.0, 115.0 0.0
B6.PWD-Chr16 m 116.0 6.22   2   4.4 0.0536 112.0, 121.0 0.43
B6.PWD-Chr17 f 116.0 2.02   7 0.764 0.0175 113.0, 119.0 0.28
B6.PWD-Chr17 m 110.0 1.32   8 0.468 0.012 109.0, 113.0 -0.39
B6.PWD-Chr18 f 109.0 1.42   7 0.535 0.013 108.0, 112.0 -0.7
B6.PWD-Chr18 m 108.0 1.19   7 0.449 0.011 106.0, 109.0 -0.67
B6.PWD-Chr19 f 110.0 3.63   4 1.81 0.0328 106.0, 114.0 -0.56
B6.PWD-Chr19 m 108.0 1.85   6 0.756 0.0171 106.0, 110.0 -0.67
B6.PWD-Chr3 m 117.0 10.3   7 3.91 0.0888 103.0, 132.0 0.56
B6.PWD-Chr5 f 110.0 7.12   7 2.69 0.0648 97.8, 121.0 -0.56
B6.PWD-Chr5 m 109.0 8.56   8 3.03 0.0787 95.3, 121.0 -0.53
B6.PWD-Chr6 f 117.0 4.65   8 1.64 0.0397 110.0, 124.0 0.42
B6.PWD-Chr6 m 111.0 2.43   8 0.858 0.0219 105.0, 113.0 -0.26
B6.PWD-ChrX.1 f 102.0 2.2   4 1.1 0.0216 99.5, 104.0 -1.67
B6.PWD-ChrX.1 m 102.0 6.36   3 3.67 0.0624 94.5, 106.0 -1.49
B6.PWD-ChrX.2 m 101.0 2.82   6 1.15 0.028 96.7, 104.0 -1.62
B6.PWD-ChrX.3 f 101.0 0.643   3 0.371 0.00636 100.0, 102.0 -1.81
B6.PWD-ChrX.3 m 101.0 3.85   7 1.46 0.0381 95.3, 106.0 -1.62
B6.PWD-ChrY f 100.0 5.1   6 2.08 0.0509 93.5, 107.0 -1.95
B6.PWD-ChrY m 105.0 1.67   6 0.683 0.016 103.0, 107.0 -1.08
B6.PWD-mt f 104.0 1.06   4 0.531 0.0102 103.0, 105.0 -1.39
B6.PWD-mt m 101.0 3.66   3 2.11 0.0364 97.1, 104.0 -1.62
C57BL/6J f 116.0 5.24   5 2.34 0.045 112.0, 125.0 0.28
C57BL/6J m 115.0 2.19   7 0.826 0.019 112.0, 117.0 0.29
PWD/PhJ f 118.0 3.16   3 1.83 0.0269 115.0, 121.0 0.56
PWD/PhJ m 122.0 4.12   5 1.84 0.0339 117.0, 128.0 1.25


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
B6.PWD-Chr1 f 114.65 1.4072 117.4227 111.8773
B6.PWD-Chr1 m 113.525 1.4072 116.2977 110.7523
B6.PWD-Chr10.1 f 119.85 1.9901 123.7712 115.9288
B6.PWD-Chr10.1 m 123.325 1.4072 126.0977 120.5523
B6.PWD-Chr10.2 f 125.0 1.78 128.5073 121.4927
B6.PWD-Chr10.2 m 124.04 1.2587 126.52 121.56
B6.PWD-Chr10.3 f 122.0833 1.6249 125.285 118.8816
B6.PWD-Chr10.3 m 114.3667 1.6249 117.5684 111.165
B6.PWD-Chr11.1 f 118.6571 1.5044 121.6213 115.693
B6.PWD-Chr11.1 m 119.95 1.149 122.2139 117.6861
B6.PWD-Chr11.2 f 113.775 1.4072 116.5477 111.0023
B6.PWD-Chr11.2 m 117.6444 1.3267 120.2586 115.0303
B6.PWD-Chr11.3 f 121.71 1.2587 124.19 119.23
B6.PWD-Chr11.3 m 120.9 1.4072 123.6727 118.1273
B6.PWD-Chr12 f 119.4 2.8144 124.9455 113.8545
B6.PWD-Chr12 m 114.2667 1.6249 117.4684 111.065
B6.PWD-Chr14 f 121.2 1.5044 124.1642 118.2358
B6.PWD-Chr14 m 121.0571 1.5044 124.0213 118.093
B6.PWD-Chr15 f 114.48 1.78 117.9873 110.9727
B6.PWD-Chr15 m 114.0 2.298 118.5279 109.4721
B6.PWD-Chr16 f 113.6333 1.6249 116.835 110.4316
B6.PWD-Chr16 m 116.2 2.8144 121.7455 110.6545
B6.PWD-Chr17 f 115.5429 1.5044 118.507 112.5787
B6.PWD-Chr17 m 110.3 1.4072 113.0727 107.5273
B6.PWD-Chr18 f 108.9714 1.5044 111.9356 106.0072
B6.PWD-Chr18 m 107.8571 1.5044 110.8213 104.893
B6.PWD-Chr19 f 110.45 1.9901 114.3712 106.5288
B6.PWD-Chr19 m 108.4333 1.6249 111.635 105.2316
B6.PWD-Chr5 f 109.9286 1.5044 112.8928 106.9644
B6.PWD-Chr5 m 108.8 1.4072 111.5727 106.0273
B6.PWD-Chr6 f 117.1375 1.4072 119.9102 114.3648
B6.PWD-Chr6 m 110.6875 1.4072 113.4602 107.9148
B6.PWD-ChrX.1 f 101.55 1.9901 105.4712 97.6288
B6.PWD-ChrX.1 m 101.8 2.298 106.3279 97.2721
B6.PWD-ChrX.3 f 101.1333 2.298 105.6612 96.6055
B6.PWD-ChrX.3 m 100.9571 1.5044 103.9213 97.993
B6.PWD-ChrY f 100.1333 1.6249 103.335 96.9316
B6.PWD-ChrY m 104.5 1.6249 107.7017 101.2983
B6.PWD-mt f 104.325 1.9901 108.2462 100.4038
B6.PWD-mt m 100.6 2.298 105.1279 96.0721
C57BL/6J f 116.44 1.78 119.9473 112.9327
C57BL/6J m 115.3286 1.5044 118.2928 112.3644
PWD/PhJ f 117.7333 2.298 122.2612 113.2055
PWD/PhJ m 121.52 1.78 125.0273 118.0127


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
B6.PWD-Chr1 both 114.0875 0.9951 116.0481 112.1269
B6.PWD-Chr10.1 both 121.5875 1.2187 123.9888 119.1862
B6.PWD-Chr10.2 both 124.52 1.09 126.6678 122.3722
B6.PWD-Chr10.3 both 118.225 1.149 120.4889 115.9611
B6.PWD-Chr11.1 both 119.3036 0.9465 121.1685 117.4386
B6.PWD-Chr11.2 both 115.7097 0.967 117.6151 113.8043
B6.PWD-Chr11.3 both 121.305 0.944 123.165 119.445
B6.PWD-Chr12 both 116.8333 1.6249 120.035 113.6316
B6.PWD-Chr14 both 121.1286 1.0638 123.2246 119.0326
B6.PWD-Chr15 both 114.24 1.4534 117.1037 111.3763
B6.PWD-Chr16 both 114.9167 1.6249 118.1184 111.715
B6.PWD-Chr17 both 112.9214 1.03 114.9509 110.892
B6.PWD-Chr18 both 108.4143 1.0638 110.5103 106.3183
B6.PWD-Chr19 both 109.4417 1.2846 111.9728 106.9105
B6.PWD-Chr5 both 109.3643 1.03 111.3937 107.3348
B6.PWD-Chr6 both 113.9125 0.9951 115.8731 111.9519
B6.PWD-ChrX.1 both 101.675 1.52 104.6699 98.6801
B6.PWD-ChrX.3 both 101.0452 1.3733 103.7512 98.3393
B6.PWD-ChrY both 102.3167 1.149 104.5806 100.0527
B6.PWD-mt both 102.4625 1.52 105.4574 99.4676
C57BL/6J both 115.8843 1.1653 118.1803 113.5882
PWD/PhJ both 119.6267 1.4534 122.4903 116.763




GWAS analysis not available: Strain panel must be either Inbred, HMDP, BXD, BXH, CXB, or AXB/BXA