Project measure / variable:   Donahue4   duration_perimeter

ID, description, units MPD:41340   duration_perimeter   duration of activity along perimeter of arena, thigmotaxis, 10 min test   [s]  
Data set, strains Donahue4   B6.PWD consomic w/par   28 strains     sex: both     age: 6wks
Procedure open field test
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  STRAIN COMPARISON PLOT
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Donahue4 - duration of activity along perimeter of arena, thigmotaxis, 10 min test



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested28 strains28 strains
Mean of the strain means521   s 512   s
Median of the strain means526   s 510   s
SD of the strain means± 15.1 ± 15.0
Coefficient of variation (CV)0.0290 0.0293
Min–max range of strain means491   –   543   s 467   –   534   s
Mean sample size per strain7.8   mice 7.7   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 7783.3152 7783.3152 10.4671 0.0013
strain 27 75542.9713 2797.8878 3.7626 < 0.0001
sex:strain 27 19166.5646 709.8728 0.9546 0.5326
Residuals 371 275875.6749 743.6002


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
B6.PWD-Chr1 f 543.0 19.5   8 6.88 0.0359 504.0, 568.0 1.45
B6.PWD-Chr1 m 529.0 27.9   8 9.86 0.0528 488.0, 578.0 1.12
B6.PWD-Chr10.1 f 518.0 20.3   8 7.19 0.0393 491.0, 548.0 -0.2
B6.PWD-Chr10.1 m 510.0 23.3   8 8.24 0.0457 484.0, 539.0 -0.14
B6.PWD-Chr10.2 f 491.0 23.7   8 8.39 0.0484 465.0, 543.0 -1.99
B6.PWD-Chr10.2 m 505.0 36.4   8 12.9 0.0721 439.0, 546.0 -0.47
B6.PWD-Chr10.3 f 532.0 28.9   8 10.2 0.0543 502.0, 585.0 0.73
B6.PWD-Chr10.3 m 511.0 34.3   8 12.1 0.0671 443.0, 542.0 -0.07
B6.PWD-Chr11.1 f 526.0 13.5   8 4.79 0.0257 501.0, 549.0 0.33
B6.PWD-Chr11.1 m 514.0 29.1   8 10.3 0.0567 463.0, 557.0 0.13
B6.PWD-Chr11.2 f 529.0 19.4   7 7.31 0.0366 505.0, 552.0 0.53
B6.PWD-Chr11.2 m 527.0 18.8   7 7.12 0.0358 504.0, 553.0 0.99
B6.PWD-Chr11.3 f 491.0 50.9   8 18.0 0.104 401.0, 567.0 -1.99
B6.PWD-Chr11.3 m 507.0 39.1   8 13.8 0.0771 449.0, 558.0 -0.34
B6.PWD-Chr12 f 519.0 34.9   8 12.3 0.0671 475.0, 572.0 -0.13
B6.PWD-Chr12 m 499.0 29.4   8 10.4 0.0588 454.0, 531.0 -0.87
B6.PWD-Chr13 f 526.0 26.3   8 9.31 0.05 484.0, 566.0 0.33
B6.PWD-Chr13 m 526.0 23.1   8 8.17 0.044 487.0, 550.0 0.92
B6.PWD-Chr14 f 501.0 25.7   8 9.1 0.0514 463.0, 540.0 -1.33
B6.PWD-Chr14 m 499.0 28.5   8 10.1 0.0571 454.0, 532.0 -0.87
B6.PWD-Chr15 f 520.0 24.6   8 8.7 0.0473 468.0, 550.0 -0.07
B6.PWD-Chr15 m 518.0 21.1   8 7.47 0.0408 482.0, 550.0 0.39
B6.PWD-Chr16 f 530.0 15.7   8 5.56 0.0297 512.0, 556.0 0.59
B6.PWD-Chr16 m 530.0 21.2   8 7.5 0.04 503.0, 555.0 1.19
B6.PWD-Chr17 f 508.0 40.2   8 14.2 0.0791 438.0, 547.0 -0.86
B6.PWD-Chr17 m 501.0 32.5   6 13.3 0.0648 440.0, 526.0 -0.74
B6.PWD-Chr18 f 531.0 25.0   8 8.85 0.0472 507.0, 576.0 0.66
B6.PWD-Chr18 m 510.0 24.8   8 8.78 0.0487 471.0, 544.0 -0.14
B6.PWD-Chr19 f 534.0 15.0   8 5.3 0.0281 500.0, 548.0 0.86
B6.PWD-Chr19 m 506.0 27.4   7 10.4 0.0542 473.0, 543.0 -0.41
B6.PWD-Chr2 f 541.0 30.1   8 10.6 0.0555 485.0, 580.0 1.32
B6.PWD-Chr2 m 534.0 30.1   8 10.6 0.0563 489.0, 569.0 1.46
B6.PWD-Chr3 f 504.0 30.0   8 10.6 0.0596 464.0, 541.0 -1.13
B6.PWD-Chr3 m 505.0 6.18   3 3.57 0.0122 501.0, 512.0 -0.47
B6.PWD-Chr5 f 535.0 23.5   8 8.31 0.0439 491.0, 565.0 0.92
B6.PWD-Chr5 m 530.0 8.21   8 2.9 0.0155 518.0, 545.0 1.19
B6.PWD-Chr6 f 536.0 54.0   8 19.1 0.101 408.0, 577.0 0.99
B6.PWD-Chr6 m 524.0 27.1   8 9.6 0.0518 481.0, 557.0 0.79
B6.PWD-Chr8 f 537.0 24.4   5 10.9 0.0455 514.0, 571.0 1.06
B6.PWD-Chr8 m 525.0 15.0   6 6.12 0.0285 518.0, 556.0 0.86
B6.PWD-Chr9 f 518.0 16.8   8 5.93 0.0324 493.0, 548.0 -0.2
B6.PWD-Chr9 m 502.0 27.7   8 9.8 0.0552 454.0, 542.0 -0.67
B6.PWD-ChrX.1 f 516.0 28.5   6 11.6 0.0552 481.0, 562.0 -0.33
B6.PWD-ChrX.1 m 512.0 18.8   8 6.66 0.0368 482.0, 538.0 -0.01
B6.PWD-ChrX.2 f 511.0 25.8   8 9.14 0.0505 463.0, 539.0 -0.66
B6.PWD-ChrX.2 m 534.0 12.7   7 4.79 0.0238 515.0, 548.0 1.46
B6.PWD-ChrX.3 f 534.0 20.3   8 7.19 0.0381 506.0, 568.0 0.86
B6.PWD-ChrX.3 m 507.0 21.2   8 7.51 0.0418 470.0, 531.0 -0.34
B6.PWD-ChrY f 531.0 9.35   7 3.53 0.0176 521.0, 545.0 0.66
B6.PWD-ChrY m 499.0 19.3   7 7.3 0.0387 458.0, 521.0 -0.87
B6.PWD-mt f 497.0 27.1   8 9.58 0.0545 456.0, 532.0 -1.59
B6.PWD-mt m 491.0 32.4   8 11.5 0.0661 454.0, 552.0 -1.41
C57BL/6J f 503.0 29.7   8 10.5 0.0591 459.0, 546.0 -1.19
C57BL/6J m 467.0 22.3   8 7.88 0.0477 443.0, 512.0 -3.0
PWD/PhJ f 527.0 30.7   7 11.6 0.0583 494.0, 584.0 0.39
PWD/PhJ m 517.0 32.9   8 11.6 0.0636 443.0, 548.0 0.33


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
B6.PWD-Chr1 f 542.575 9.6411 561.533 523.617
B6.PWD-Chr1 m 528.5875 9.6411 547.5455 509.6295
B6.PWD-Chr10.1 f 517.95 9.6411 536.908 498.992
B6.PWD-Chr10.1 m 509.8875 9.6411 528.8455 490.9295
B6.PWD-Chr10.2 f 490.5125 9.6411 509.4705 471.5545
B6.PWD-Chr10.2 m 505.1375 9.6411 524.0955 486.1795
B6.PWD-Chr10.3 f 531.825 9.6411 550.783 512.867
B6.PWD-Chr10.3 m 510.85 9.6411 529.808 491.892
B6.PWD-Chr11.1 f 526.175 9.6411 545.133 507.217
B6.PWD-Chr11.1 m 513.7875 9.6411 532.7455 494.8295
B6.PWD-Chr11.2 f 529.1429 10.3067 549.4098 508.8759
B6.PWD-Chr11.2 m 527.0 10.3067 547.2669 506.7331
B6.PWD-Chr11.3 f 490.7875 9.6411 509.7455 471.8295
B6.PWD-Chr11.3 m 507.25 9.6411 526.208 488.292
B6.PWD-Chr12 f 519.0625 9.6411 538.0205 500.1045
B6.PWD-Chr12 m 499.3625 9.6411 518.3205 480.4045
B6.PWD-Chr13 f 526.4875 9.6411 545.4455 507.5295
B6.PWD-Chr13 m 525.7125 9.6411 544.6705 506.7545
B6.PWD-Chr14 f 501.275 9.6411 520.233 482.317
B6.PWD-Chr14 m 498.75 9.6411 517.708 479.792
B6.PWD-Chr15 f 519.9875 9.6411 538.9455 501.0295
B6.PWD-Chr15 m 518.2875 9.6411 537.2455 499.3295
B6.PWD-Chr16 f 529.7 9.6411 548.658 510.742
B6.PWD-Chr16 m 530.3375 9.6411 549.2955 511.3795
B6.PWD-Chr17 f 508.075 9.6411 527.033 489.117
B6.PWD-Chr17 m 501.4833 11.1325 523.3741 479.5925
B6.PWD-Chr18 f 530.5125 9.6411 549.4705 511.5545
B6.PWD-Chr18 m 510.2375 9.6411 529.1955 491.2795
B6.PWD-Chr19 f 533.825 9.6411 552.783 514.867
B6.PWD-Chr19 m 505.5857 10.3067 525.8526 485.3188
B6.PWD-Chr2 f 541.4125 9.6411 560.3705 522.4545
B6.PWD-Chr2 m 533.9 9.6411 552.858 514.942
B6.PWD-Chr3 f 504.1 9.6411 523.058 485.142
B6.PWD-Chr3 m 504.9667 15.7438 535.9249 474.0084
B6.PWD-Chr5 f 535.0375 9.6411 553.9955 516.0795
B6.PWD-Chr5 m 529.7875 9.6411 548.7455 510.8295
B6.PWD-Chr6 f 535.5 9.6411 554.458 516.542
B6.PWD-Chr6 m 523.7125 9.6411 542.6705 504.7545
B6.PWD-Chr8 f 536.66 12.1951 560.6402 512.6798
B6.PWD-Chr8 m 525.3833 11.1325 547.2741 503.4925
B6.PWD-Chr9 f 517.7875 9.6411 536.7455 498.8295
B6.PWD-Chr9 m 502.1125 9.6411 521.0705 483.1545
B6.PWD-ChrX.1 f 516.3167 11.1325 538.2075 494.4259
B6.PWD-ChrX.1 m 511.65 9.6411 530.608 492.692
B6.PWD-ChrX.2 f 511.275 9.6411 530.233 492.317
B6.PWD-ChrX.2 m 533.5714 10.3067 553.8384 513.3045
B6.PWD-ChrX.3 f 534.2 9.6411 553.158 515.242
B6.PWD-ChrX.3 m 507.2875 9.6411 526.2455 488.3295
B6.PWD-ChrY f 530.6857 10.3067 550.9526 510.4188
B6.PWD-ChrY m 499.3714 10.3067 519.6384 479.1045
B6.PWD-mt f 497.4375 9.6411 516.3955 478.4795
B6.PWD-mt m 490.6125 9.6411 509.5705 471.6545
C57BL/6J f 502.5125 9.6411 521.4705 483.5545
C57BL/6J m 467.0875 9.6411 486.0455 448.1295
PWD/PhJ f 527.2429 10.3067 547.5098 506.9759
PWD/PhJ m 517.4875 9.6411 536.4455 498.5295


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
B6.PWD-Chr1 both 535.5812 6.8173 548.9866 522.1759
B6.PWD-Chr10.1 both 513.9187 6.8173 527.3241 500.5134
B6.PWD-Chr10.2 both 497.825 6.8173 511.2303 484.4197
B6.PWD-Chr10.3 both 521.3375 6.8173 534.7428 507.9322
B6.PWD-Chr11.1 both 519.9812 6.8173 533.3866 506.5759
B6.PWD-Chr11.2 both 528.0714 7.288 542.4023 513.7405
B6.PWD-Chr11.3 both 499.0187 6.8173 512.4241 485.6134
B6.PWD-Chr12 both 509.2125 6.8173 522.6178 495.8072
B6.PWD-Chr13 both 526.1 6.8173 539.5053 512.6947
B6.PWD-Chr14 both 500.0125 6.8173 513.4178 486.6072
B6.PWD-Chr15 both 519.1375 6.8173 532.5428 505.7322
B6.PWD-Chr16 both 530.0187 6.8173 543.4241 516.6134
B6.PWD-Chr17 both 504.7792 7.3635 519.2586 490.2998
B6.PWD-Chr18 both 520.375 6.8173 533.7803 506.9697
B6.PWD-Chr19 both 519.7054 7.0565 533.5812 505.8295
B6.PWD-Chr2 both 537.6562 6.8173 551.0616 524.2509
B6.PWD-Chr3 both 504.5333 9.2306 522.6842 486.3825
B6.PWD-Chr5 both 532.4125 6.8173 545.8178 519.0072
B6.PWD-Chr6 both 529.6062 6.8173 543.0116 516.2009
B6.PWD-Chr8 both 531.0217 8.2561 547.2563 514.787
B6.PWD-Chr9 both 509.95 6.8173 523.3553 496.5447
B6.PWD-ChrX.1 both 513.9833 7.3635 528.4627 499.5039
B6.PWD-ChrX.2 both 522.4232 7.0565 536.299 508.5474
B6.PWD-ChrX.3 both 520.7437 6.8173 534.1491 507.3384
B6.PWD-ChrY both 515.0286 7.288 529.3595 500.6977
B6.PWD-mt both 494.025 6.8173 507.4303 480.6197
C57BL/6J both 484.8 6.8173 498.2053 471.3947
PWD/PhJ both 522.3652 7.0565 536.241 508.4894




GWAS analysis not available: Strain panel must be either Inbred, HMDP, BXD, BXH, CXB, or AXB/BXA