Project measure / variable:   Threadgill2   ALT_Rx300

ID, description, units MPD:39628   ALT_Rx300   alanine transaminase (serum ALT)   [IU/L]  dose: 300 mg/kg  
acetaminophen study
Data set, strains Threadgill2   inbred   5 strains     sex: m     age: 6-8wks
Procedure metabolic panel
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  STRAIN COMPARISON PLOT
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Threadgill2 - alanine transaminase (serum ALT) dose: 300 mg/kg



  MEASURE SUMMARY
Measure Summary Male
Number of strains tested5 strains
Mean of the strain means3047   IU/L
Median of the strain means3101   IU/L
SD of the strain means± 291
Coefficient of variation (CV)0.0956
Min–max range of strain means2691   –   3413   IU/L
Mean sample size per strain4.6   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
strain 4 1564828.0174 391207.0043 0.2254 0.9207
Residuals 18 31246103.2 1735894.6222


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
C3H/HeJ m 2823.0 1582.0   5 708.0 0.56 829.0, 4557.0 -0.77
C57BL/6J m 3413.0 1687.0   5 754.0 0.494 1283.0, 5221.0 1.26
DBA/2J m 3207.0 814.0   5 364.0 0.254 1772.0, 3684.0 0.55
LP/J m 3101.0 1094.0   4 547.0 0.353 2430.0, 4736.0 0.19
NZW/LacJ m 2691.0 1097.0   4 549.0 0.408 1694.0, 4164.0 -1.22


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
C3H/HeJ m 2823.2 589.2189 4061.103 1585.297
C57BL/6J m 3413.4 589.2189 4651.303 2175.497
DBA/2J m 3207.4 589.2189 4445.303 1969.497
LP/J m 3101.0 658.7668 4485.0176 1716.9824
NZW/LacJ m 2691.0 658.7668 4075.0176 1306.9824




  GWAS USING LINEAR MIXED MODELS