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Project measure / variable:   Gupta2   pressure_urethra

ID, description, units MPD:39214   pressure_urethra   urethral hydrostatic pressure at which dye is observed flowing   [cm]  
Data set, strains Gupta2   BXH   10 strains     sex: both     age: postnatal d1
Procedure renal function assay
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  STRAIN COMPARISON PLOT
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Gupta2 - urethral hydrostatic pressure at which dye is observed flowing



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested10 strains10 strains
Mean of the strain means63.8   cm 58.5   cm
Median of the strain means63.9   cm 60.0   cm
SD of the strain means± 4.44 ± 3.02
Coefficient of variation (CV)0.0696 0.0516
Min–max range of strain means57.7   –   72.0   cm 53.6   –   63.2   cm
Mean sample size per strain12.9   mice 14.2   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 1478.1328 1478.1328 15.4096 0.0001
strain 9 3030.2385 336.6932 3.51 0.0004
sex:strain 9 666.2257 74.0251 0.7717 0.6427
Residuals 254 24364.4541 95.923


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
BXH10/TyJ f 57.7 8.32   13 2.31 0.144 30.0, 60.0 -1.36
BXH10/TyJ m 53.6 12.8   14 3.41 0.238 30.0, 60.0 -1.61
BXH11/TyJ f 64.3 11.3   7 4.29 0.176 60.0, 90.0 0.12
BXH11/TyJ m 60.0 0.0   6 0.0 0.0 60.0, 60.0 0.51
BXH14/TyJ f 62.0 7.75   15 2.0 0.125 60.0, 90.0 -0.39
BXH14/TyJ m 54.4 12.1   16 3.02 0.222 30.0, 60.0 -1.34
BXH19/TyJ f 58.7 14.2   23 2.97 0.243 30.0, 90.0 -1.14
BXH19/TyJ m 60.0 0.0   11 0.0 0.0 60.0, 60.0 0.51
BXH2/TyJ f 63.8 10.6   8 3.75 0.166 60.0, 90.0 0.01
BXH2/TyJ m 60.0 0.0   12 0.0 0.0 60.0, 60.0 0.51
BXH4/TyJ f 60.0 0.0   15 0.0 0.0 60.0, 60.0 -0.85
BXH4/TyJ m 57.3 9.05   11 2.73 0.158 30.0, 60.0 -0.38
BXH6/TyJ f 64.0 10.6   15 2.73 0.165 60.0, 90.0 0.06
BXH6/TyJ m 56.0 10.6   15 2.73 0.188 30.0, 60.0 -0.81
BXH7/TyJ f 66.7 13.2   9 4.41 0.198 60.0, 90.0 0.67
BXH7/TyJ m 60.0 0.0   16 0.0 0.0 60.0, 60.0 0.51
BXH8/TyJ f 72.0 15.5   10 4.9 0.215 60.0, 90.0 1.86
BXH8/TyJ m 63.2 9.46   19 2.17 0.15 60.0, 90.0 1.58
BXH9/TyJ f 68.3 13.8   18 3.26 0.202 60.0, 90.0 1.03
BXH9/TyJ m 60.0 0.0   21 0.0 0.0 60.0, 60.0 0.51


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
BXH10/TyJ f 57.6923 2.7164 63.0418 52.3428
BXH10/TyJ m 53.5714 2.6176 58.7263 48.4165
BXH11/TyJ f 64.2857 3.7018 71.5758 56.9956
BXH11/TyJ m 60.0 3.9984 67.8742 52.1258
BXH14/TyJ f 62.0 2.5288 66.9801 57.0199
BXH14/TyJ m 54.375 2.4485 59.197 49.553
BXH19/TyJ f 58.6957 2.0422 62.7174 54.6739
BXH19/TyJ m 60.0 2.953 65.8155 54.1845
BXH2/TyJ f 63.75 3.4627 70.5693 56.9307
BXH2/TyJ m 60.0 2.8273 65.5679 54.4321
BXH4/TyJ f 60.0 2.5288 64.9801 55.0199
BXH4/TyJ m 57.2727 2.953 63.0882 51.4572
BXH6/TyJ f 64.0 2.5288 68.9801 59.0199
BXH6/TyJ m 56.0 2.5288 60.9801 51.0199
BXH7/TyJ f 66.6667 3.2647 73.096 60.2374
BXH7/TyJ m 60.0 2.4485 64.822 55.178
BXH8/TyJ f 72.0 3.0971 78.0994 65.9006
BXH8/TyJ m 63.1579 2.2469 67.5828 58.733
BXH9/TyJ f 68.3333 2.3085 72.8795 63.7871
BXH9/TyJ m 60.0 2.1372 64.209 55.791


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
BXH10/TyJ both 55.6319 1.8862 59.3464 51.9174
BXH11/TyJ both 62.1429 2.7244 67.5082 56.7775
BXH14/TyJ both 58.1875 1.76 61.6535 54.7215
BXH19/TyJ both 59.3478 1.7952 62.8832 55.8125
BXH2/TyJ both 61.875 2.2352 66.2768 57.4732
BXH4/TyJ both 58.6364 1.9439 62.4646 54.8081
BXH6/TyJ both 60.0 1.7881 63.5215 56.4785
BXH7/TyJ both 63.3333 2.0404 67.3516 59.315
BXH8/TyJ both 67.5789 1.9132 71.3466 63.8112
BXH9/TyJ both 64.1667 1.573 67.2644 61.069




  GWAS USING LINEAR MIXED MODELS