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Project measure / variable:   Bopp1   luciferase_brain

ID, description, units MPD:36404   luciferase_brain   percentage of parasites in brain relative to all organs tested   [%]  
Plasmodium berghei study
Data set, strains Bopp1   inbred   28 strains     sex: both     age: 8-12wks
Procedure health assessment
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  STRAIN COMPARISON PLOT
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Bopp1 - percentage of parasites in brain relative to all organs tested



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested26 strains25 strains
Mean of the strain means4.07   % 3.54   %
Median of the strain means3.62   % 3.03   %
SD of the strain means± 2.02 ± 1.89
Coefficient of variation (CV)0.496 0.535
Min–max range of strain means1.81   –   10.1   % 0.710   –   7.91   %
Mean sample size per strain1.9   mice 1.9   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 18.4029 18.4029 1.5118 0.2278
strain 13 171.621 13.2016 1.0845 0.4055
sex:strain 13 88.1306 6.7793 0.5569 0.8692
Residuals 32 389.5396 12.1731


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 3.76 1.2   2   0.85 0.32 2.91, 4.61 -0.15
129S1/SvImJ m 3.03 3.13   2   2.21 1.04 0.81, 5.24 -0.27
A/J f 2.7 1.1   2   0.775 0.407 1.92, 3.47 -0.68
A/J m 3.43 1.53   2   1.08 0.447 2.35, 4.52 -0.06
AKR/J f 5.96 7.21   4 3.61 1.21 1.92, 16.8 0.94
AKR/J m 2.75 1.01   3 0.583 0.367 1.96, 3.89 -0.42
BTBR T+ Itpr3tf/J f 6.54 7.25   2   5.12 1.11 1.42, 11.7 1.22
BTBR T+ Itpr3tf/J m 2.06 0.0141   2   0.01 0.00687 2.05, 2.07 -0.78
BUB/BnJ f 3.79 0.728   2   0.515 0.192 3.28, 4.31 -0.14
BUB/BnJ m 5.48 4.68   2   3.31 0.854 2.17, 8.79 1.02
C3H/HeJ f 3.5 0.58   2   0.41 0.166 3.09, 3.91 -0.28
C3H/HeJ m 3.44 0.297   2   0.21 0.0863 3.23, 3.65 -0.05
C57BL/6J m 3.12 1.29   2   0.915 0.415 2.2, 4.03 -0.22
C57BR/cdJ f 4.56 1.13   2   0.8 0.248 3.76, 5.36 0.24
C57BR/cdJ m 3.12 1.63   2   1.15 0.521 1.97, 4.27 -0.22
C58/J f 3.21 1.39   2   0.985 0.433 2.23, 4.2 -0.43
C58/J m 2.03 1.32   2   0.93 0.648 1.1, 2.96 -0.8
CBA/J f 2.32 0.0   1   0.0 0.0 2.32, 2.32 -0.87
CBA/J m 1.47 0.191   2   0.135 0.13 1.33, 1.6 -1.09
CZECHII/EiJ f 4.54 0.0   1   0.0 0.0 4.54, 4.54 0.23
CZECHII/EiJ m 2.93 0.849   2   0.6 0.29 2.33, 3.53 -0.32
DBA/2J f 6.26 1.52   3 0.879 0.243 4.97, 7.94 1.08
DBA/2J m 3.82 0.0   1   0.0 0.0 3.82, 3.82 0.15
I/LnJ f 3.93 1.02   2   0.72 0.259 3.21, 4.65 -0.07
I/LnJ m 2.22 0.0   1   0.0 0.0 2.22, 2.22 -0.7
KK/HlJ f 6.64 5.35   2   3.78 0.805 2.86, 10.4 1.27
KK/HlJ m 2.71 0.389   2   0.275 0.144 2.43, 2.98 -0.44
LG/J f 2.25 0.728   2   0.515 0.323 1.74, 2.77 -0.9
MRL/MpJ f 2.13 1.48   2   1.05 0.697 1.08, 3.18 -0.96
NOD/ShiLtJ f 10.1 2.91   3 1.68 0.289 6.81, 12.4 2.99
NOD/ShiLtJ m 7.36 2.64   2   1.87 0.359 5.49, 9.22 2.02
NON/ShiLtJ f 3.45 0.0   1   0.0 0.0 3.45, 3.45 -0.31
NON/ShiLtJ m 1.97 0.453   2   0.32 0.23 1.65, 2.29 -0.83
NZO/HlLtJ f 2.3 1.27   2   0.9 0.553 1.4, 3.2 -0.88
NZO/HlLtJ m 7.46 8.34   2   5.9 1.12 1.56, 13.3 2.07
NZW/LacJ f 2.15 0.0   1   0.0 0.0 2.15, 2.15 -0.95
NZW/LacJ m 4.56 0.0   1   0.0 0.0 4.56, 4.56 0.54
PERA/EiJ f 7.69 7.78   2   5.5 1.01 2.19, 13.2 1.79
P/J f 3.37 2.98   2   2.11 0.885 1.26, 5.48 -0.35
P/J m 7.91 0.0   1   0.0 0.0 7.91, 7.91 2.31
PL/J f 2.35 0.127   2   0.09 0.0542 2.26, 2.44 -0.85
PL/J m 2.46 0.969   2   0.685 0.393 1.78, 3.15 -0.57
RIIIS/J m 5.02 1.37   2   0.97 0.273 4.05, 5.99 0.78
SJL/J f 3.75 0.424   2   0.3 0.113 3.45, 4.05 -0.16
SJL/J m 1.92 0.0   1   0.0 0.0 1.92, 1.92 -0.86
SM/J f 2.77 1.82   2   1.28 0.655 1.49, 4.06 -0.64
SM/J m 0.71 0.481   2   0.34 0.677 0.37, 1.05 -1.5
SWR/J f 4.0 1.05   2   0.74 0.262 3.26, 4.74 -0.03
SWR/J m 4.96 2.1   2   1.48 0.423 3.48, 6.45 0.75
WSB/EiJ f 1.81 0.0   1   0.0 0.0 1.81, 1.81 -1.12
WSB/EiJ m 2.61 1.07   3 0.62 0.411 1.81, 3.83 -0.49


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f 3.76 2.4671 8.7853 0.0
129S1/SvImJ m 3.025 2.4671 8.0503 0.0
A/J f 2.695 2.4671 7.7203 0.0
A/J m 3.435 2.4671 8.4603 0.0
AKR/J f 5.9575 1.7445 9.5109 2.4041
AKR/J m 2.7533 2.0144 6.8565 0.0
BTBR T+ Itpr3tf/J f 6.545 2.4671 11.5703 1.5197
BTBR T+ Itpr3tf/J m 2.06 2.4671 7.0853 0.0
BUB/BnJ f 3.795 2.4671 8.8203 0.0
BUB/BnJ m 5.48 2.4671 10.5053 0.4547
C3H/HeJ f 3.5 2.4671 8.5253 0.0
C3H/HeJ m 3.44 2.4671 8.4653 0.0
C57BR/cdJ f 4.56 2.4671 9.5853 0.0
C57BR/cdJ m 3.12 2.4671 8.1453 0.0
C58/J f 3.215 2.4671 8.2403 0.0
C58/J m 2.03 2.4671 7.0553 0.0
KK/HlJ f 6.64 2.4671 11.6653 1.6147
KK/HlJ m 2.705 2.4671 7.7303 0.0
NOD/ShiLtJ f 10.0767 2.0144 14.1798 5.9735
NOD/ShiLtJ m 7.355 2.4671 12.3803 2.3297
NZO/HlLtJ f 2.3 2.4671 7.3253 0.0
NZO/HlLtJ m 7.455 2.4671 12.4803 2.4297
PL/J f 2.35 2.4671 7.3753 0.0
PL/J m 2.465 2.4671 7.4903 0.0
SM/J f 2.775 2.4671 7.8003 0.0
SM/J m 0.71 2.4671 5.7353 0.0
SWR/J f 4.0 2.4671 9.0253 0.0
SWR/J m 4.965 2.4671 9.9903 0.0


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ both 3.3925 1.7445 6.9459 0.0
A/J both 3.065 1.7445 6.6184 0.0
AKR/J both 4.3554 1.3324 7.0694 1.6414
BTBR T+ Itpr3tf/J both 4.3025 1.7445 7.8559 0.7491
BUB/BnJ both 4.6375 1.7445 8.1909 1.0841
C3H/HeJ both 3.47 1.7445 7.0234 0.0
C57BR/cdJ both 3.84 1.7445 7.3934 0.2866
C58/J both 2.6225 1.7445 6.1759 0.0
KK/HlJ both 4.6725 1.7445 8.2259 1.1191
NOD/ShiLtJ both 8.7158 1.5925 11.9597 5.472
NZO/HlLtJ both 4.8775 1.7445 8.4309 1.3241
PL/J both 2.4075 1.7445 5.9609 0.0
SM/J both 1.7425 1.7445 5.2959 0.0
SWR/J both 4.4825 1.7445 8.0359 0.9291




  GWAS USING LINEAR MIXED MODELS