Project measure / variable:   Rusyn2   DCV_cysteine24_tce

ID, description, units MPD:36187   DCV_cysteine24_tce   DCV cysteine (serum DCVC x 10-3)   [nmol/mL]  24h after treatment  
trichloroethylene study
Data set, strains Rusyn2   inbred   7 strains     sex: m     age: 7wks
Procedure drug and metabolite quantification
Ontology mappings

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  STRAIN COMPARISON PLOT
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Rusyn2 - DCV cysteine (serum DCVC x 10-3) 24h after treatment



  MEASURE SUMMARY
Measure Summary Male
Number of strains tested7 strains
Mean of the strain means0.880   nmol/mL
Median of the strain means0.886   nmol/mL
SD of the strain means± 0.328
Coefficient of variation (CV)0.373
Min–max range of strain means0.490   –   1.39   nmol/mL
Mean sample size per strain1.9   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
strain 2 0.9427 0.4713 11.363 0.0091
Residuals 6 0.2489 0.0415


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
B6C3F1/J m 0.613 0.0   1   0.0 0.0 0.613, 0.613 -0.81
C3H/HeJ m 1.13 0.0   1   0.0 0.0 1.13, 1.13 0.76
C57BL/6J m 1.04 0.0   1   0.0 0.0 1.04, 1.04 0.49
FVB/NJ m 0.49 0.0   1   0.0 0.0 0.49, 0.49 -1.19
KK/HlJ m 0.886 0.353   3 0.204 0.398 0.479, 1.09 0.02
MOLF/EiJ m 1.39 0.0   3 0.0 0.0 1.39, 1.39 1.56
NZW/LacJ m 0.608 0.0   3 0.0 0.0 0.608, 0.608 -0.83


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
KK/HlJ m 0.8863 0.1176 1.1741 0.5986
MOLF/EiJ m 1.39 0.1176 1.6777 1.1023
NZW/LacJ m 0.608 0.1176 0.8957 0.3203




  GWAS USING LINEAR MIXED MODELS