Project measure / variable:   Rusyn2   DCV_cysteine8_tce

ID, description, units MPD:36186   DCV_cysteine8_tce   DCV cysteine (serum DCVC x 10-3)   [nmol/mL]  8h after treatment  
trichloroethylene study
Data set, strains Rusyn2   inbred   13 strains     sex: m     age: 7wks
Procedure drug and metabolite quantification
Ontology mappings

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  STRAIN COMPARISON PLOT
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Rusyn2 - DCV cysteine (serum DCVC x 10-3) 8h after treatment



  MEASURE SUMMARY
Measure Summary Male
Number of strains tested13 strains
Mean of the strain means1.51   nmol/mL
Median of the strain means1.31   nmol/mL
SD of the strain means± 0.947
Coefficient of variation (CV)0.628
Min–max range of strain means0.500   –   3.56   nmol/mL
Mean sample size per strain1.8   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
strain 6 15.8006 2.6334 7.2593 0.0025
Residuals 11 3.9904 0.3628


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ m 3.11 0.0   1   0.0 0.0 3.11, 3.11 1.69
A/J m 0.612 0.0   1   0.0 0.0 0.612, 0.612 -0.95
B6C3F1/J m 2.06 1.33   3 0.765 0.644 0.535, 2.95 0.58
BALB/cByJ m 1.31 0.0   1   0.0 0.0 1.31, 1.31 -0.21
BTBR T+ Itpr3tf/J m 1.91 0.0   2   0.0 0.0 1.91, 1.91 0.42
C57BL/6J m 1.52 0.0   1   0.0 0.0 1.52, 1.52 0.01
CAST/EiJ m 1.56 0.0   1   0.0 0.0 1.56, 1.56 0.05
DBA/2J m 0.853 0.487   3 0.281 0.57 0.508, 1.41 -0.69
FVB/NJ m 0.5 0.0219   2   0.0155 0.0438 0.485, 0.516 -1.07
KK/HlJ m 0.903 0.0277   3 0.016 0.0307 0.871, 0.919 -0.64
MOLF/EiJ m 3.56 0.0   2   0.0 0.0 3.56, 3.56 2.16
NOD/ShiLtJ m 1.01 0.0   1   0.0 0.0 1.01, 1.01 -0.53
WSB/EiJ m 0.717 0.0   3 0.0 0.0 0.717, 0.717 -0.84


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
B6C3F1/J m 2.0583 0.3477 2.8237 1.293
BTBR T+ Itpr3tf/J m 1.91 0.4259 2.8474 0.9726
DBA/2J m 0.8533 0.3477 1.6187 0.088
FVB/NJ m 0.5005 0.4259 1.4379 0.0
KK/HlJ m 0.903 0.3477 1.6684 0.1376
MOLF/EiJ m 3.56 0.4259 4.4974 2.6226
WSB/EiJ m 0.717 0.3477 1.4824 0.0




  GWAS USING LINEAR MIXED MODELS