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Project measure / variable:   Koide2   capsaicin_4

ID, description, units MPD:35804   capsaicin_4   capsaicin solution consumption, percentage of baseline   [%]  concentration: 4 µM  
Data set, strains Koide2   wild-derived Mishima   14 strains     sex: both     age: 8-12wks
Procedure nociception assay
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  STRAIN COMPARISON PLOT
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Koide2 - capsaicin solution consumption, percentage of baseline concentration: 4 µM



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested14 strains14 strains
Mean of the strain means65.3   % 74.0   %
Median of the strain means65.7   % 75.7   %
SD of the strain means± 16.5 ± 22.9
Coefficient of variation (CV)0.253 0.310
Min–max range of strain means34.2   –   99.2   % 32.8   –   113   %
Mean sample size per strain10.0   mice 10.0   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 5250.6446 5250.6446 4.6751 0.0315
strain 13 84762.8177 6520.2167 5.8056 < 0.0001
sex:strain 13 18978.379 1459.8753 1.2999 0.2129
Residuals 252 283021.3275 1123.1005


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
BALB/cAnN f 67.3 24.8   10 7.84 0.368 41.8, 124.0 0.12
BALB/cAnN m 63.8 16.7   10 5.28 0.261 27.7, 89.2 -0.44
BFM/2Ms f 62.8 16.5   10 5.2 0.262 29.8, 81.1 -0.15
BFM/2Ms m 73.2 17.3   10 5.48 0.237 45.4, 95.7 -0.03
BLG2/Ms f 68.9 9.17   10 2.9 0.133 46.4, 78.0 0.22
BLG2/Ms m 84.5 5.44   10 1.72 0.0643 76.4, 93.6 0.46
C57BL/6J f 46.3 20.0   10 6.32 0.431 18.5, 74.9 -1.15
C57BL/6J m 39.9 21.3   10 6.73 0.533 8.58, 62.1 -1.49
CAST/EiJ f 82.4 12.9   10 4.08 0.157 63.2, 101.0 1.03
CAST/EiJ m 81.5 26.8   10 8.49 0.329 24.5, 113.0 0.33
CHD/Ms f 71.1 8.18   10 2.59 0.115 55.0, 82.6 0.35
CHD/Ms m 62.8 24.1   10 7.63 0.384 11.6, 97.5 -0.49
DBA/1J f 34.2 28.4   10 8.99 0.832 4.07, 75.0 -1.88
DBA/1J m 32.8 18.2   10 5.76 0.555 7.22, 61.5 -1.8
HMI/Ms f 59.6 34.6   10 10.9 0.58 12.8, 140.0 -0.35
HMI/Ms m 113.0 128.0   10 40.5 1.13 31.0, 473.0 1.7
JF1/MsJ f 64.0 19.8   10 6.25 0.309 37.5, 102.0 -0.08
JF1/MsJ m 86.8 56.4   10 17.8 0.65 29.9, 222.0 0.56
KJR/Ms f 71.8 17.8   10 5.62 0.247 24.8, 92.2 0.39
KJR/Ms m 78.2 14.0   10 4.41 0.179 63.2, 105.0 0.18
MSM/MsJ f 80.0 14.1   10 4.46 0.176 62.8, 101.0 0.89
MSM/MsJ m 105.0 39.5   10 12.5 0.377 71.3, 210.0 1.35
NJL/Ms f 62.6 26.2   10 8.29 0.419 21.9, 104.0 -0.17
NJL/Ms m 57.4 33.4   10 10.6 0.581 13.8, 109.0 -0.72
PGN2/Ms f 44.5 18.8   10 5.96 0.423 13.9, 61.2 -1.26
PGN2/Ms m 61.4 16.0   10 5.05 0.26 30.5, 80.7 -0.55
SWN/Ms f 99.2 18.5   10 5.85 0.186 50.8, 111.0 2.05
SWN/Ms m 95.6 13.1   10 4.14 0.137 69.0, 117.0 0.94


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
BALB/cAnN f 67.29 10.5976 88.1612 46.4188
BALB/cAnN m 63.83 10.5976 84.7012 42.9588
BFM/2Ms f 62.79 10.5976 83.6612 41.9188
BFM/2Ms m 73.2 10.5976 94.0712 52.3288
BLG2/Ms f 68.89 10.5976 89.7612 48.0188
BLG2/Ms m 84.53 10.5976 105.4012 63.6588
C57BL/6J f 46.33 10.5976 67.2012 25.4588
C57BL/6J m 39.899 10.5976 60.7702 19.0278
CAST/EiJ f 82.42 10.5976 103.2912 61.5488
CAST/EiJ m 81.47 10.5976 102.3412 60.5988
CHD/Ms f 71.13 10.5976 92.0012 50.2588
CHD/Ms m 62.83 10.5976 83.7012 41.9588
DBA/1J f 34.152 10.5976 55.0232 13.2808
DBA/1J m 32.844 10.5976 53.7152 11.9728
HMI/Ms f 59.6 10.5976 80.4712 38.7288
HMI/Ms m 113.16 10.5976 134.0312 92.2888
JF1/MsJ f 63.96 10.5976 84.8312 43.0888
JF1/MsJ m 86.81 10.5976 107.6812 65.9388
KJR/Ms f 71.77 10.5976 92.6412 50.8988
KJR/Ms m 78.15 10.5976 99.0212 57.2788
MSM/MsJ f 80.01 10.5976 100.8812 59.1388
MSM/MsJ m 104.77 10.5976 125.6412 83.8988
NJL/Ms f 62.56 10.5976 83.4312 41.6888
NJL/Ms m 57.4 10.5976 78.2712 36.5288
PGN2/Ms f 44.55 10.5976 65.4212 23.6788
PGN2/Ms m 61.4 10.5976 82.2712 40.5288
SWN/Ms f 99.19 10.5976 120.0612 78.3188
SWN/Ms m 95.6 10.5976 116.4712 74.7288


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
BALB/cAnN both 65.56 7.4937 80.3182 50.8018
BFM/2Ms both 67.995 7.4937 82.7532 53.2368
BLG2/Ms both 76.71 7.4937 91.4682 61.9518
C57BL/6J both 43.1145 7.4937 57.8727 28.3563
CAST/EiJ both 81.945 7.4937 96.7032 67.1868
CHD/Ms both 66.98 7.4937 81.7382 52.2218
DBA/1J both 33.498 7.4937 48.2562 18.7398
HMI/Ms both 86.38 7.4937 101.1382 71.6218
JF1/MsJ both 75.385 7.4937 90.1432 60.6268
KJR/Ms both 74.96 7.4937 89.7182 60.2018
MSM/MsJ both 92.39 7.4937 107.1482 77.6318
NJL/Ms both 59.98 7.4937 74.7382 45.2218
PGN2/Ms both 52.975 7.4937 67.7332 38.2168
SWN/Ms both 97.395 7.4937 112.1532 82.6368




GWAS analysis not available: Strain panel must be either Inbred, HMDP, BXD, BXH, CXB, or AXB/BXA