Project measure / variable:   Koide2   capsaicin_1

ID, description, units MPD:35803   capsaicin_1   capsaicin solution consumption, percentage of baseline   [%]  concentration: 1 µM  
Data set, strains Koide2   wild-derived Mishima   14 strains     sex: both     age: 8-12wks
Procedure nociception assay
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  STRAIN COMPARISON PLOT
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Koide2 - capsaicin solution consumption, percentage of baseline concentration: 1 µM



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested14 strains14 strains
Mean of the strain means84.6   % 88.9   %
Median of the strain means85.6   % 90.5   %
SD of the strain means± 14.0 ± 20.9
Coefficient of variation (CV)0.166 0.235
Min–max range of strain means47.9   –   99.0   % 54.7   –   134   %
Mean sample size per strain10.0   mice 10.0   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 1312.8127 1312.8127 0.826 0.3643
strain 13 60749.2393 4673.0184 2.9403 0.0005
sex:strain 13 21927.1634 1686.7049 1.0613 0.3937
Residuals 252 400505.7951 1589.3087


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
BALB/cAnN f 91.5 15.7   10 4.96 0.171 77.2, 129.0 0.49
BALB/cAnN m 67.3 14.3   10 4.52 0.212 36.3, 81.7 -1.03
BFM/2Ms f 83.1 16.4   10 5.19 0.198 42.3, 103.0 -0.11
BFM/2Ms m 87.6 15.5   10 4.91 0.177 68.0, 120.0 -0.06
BLG2/Ms f 81.6 8.72   10 2.76 0.107 60.6, 90.3 -0.21
BLG2/Ms m 94.3 4.22   10 1.33 0.0448 88.6, 101.0 0.26
C57BL/6J f 67.0 9.49   10 3.0 0.142 51.6, 84.3 -1.25
C57BL/6J m 61.4 14.9   10 4.72 0.243 39.8, 88.2 -1.32
CAST/EiJ f 95.9 16.6   10 5.24 0.173 71.7, 115.0 0.8
CAST/EiJ m 94.4 18.1   10 5.73 0.192 59.4, 123.0 0.26
CHD/Ms f 81.9 32.6   10 10.3 0.398 51.3, 163.0 -0.19
CHD/Ms m 80.2 23.9   10 7.55 0.298 21.8, 115.0 -0.42
DBA/1J f 47.9 29.2   10 9.25 0.611 7.68, 98.9 -2.61
DBA/1J m 54.7 18.6   10 5.89 0.341 15.7, 81.2 -1.63
HMI/Ms f 83.1 43.2   10 13.7 0.52 34.1, 193.0 -0.11
HMI/Ms m 134.0 156.0   10 49.4 1.16 26.1, 569.0 2.15
JF1/MsJ f 95.0 17.8   10 5.62 0.187 61.0, 131.0 0.74
JF1/MsJ m 101.0 75.4   10 23.9 0.749 53.0, 310.0 0.58
KJR/Ms f 98.3 13.6   10 4.3 0.138 70.7, 114.0 0.98
KJR/Ms m 83.5 19.6   10 6.2 0.235 64.2, 132.0 -0.26
MSM/MsJ f 88.1 12.1   10 3.83 0.137 70.9, 108.0 0.25
MSM/MsJ m 118.0 55.2   10 17.5 0.469 89.6, 273.0 1.39
NJL/Ms f 76.1 27.7   10 8.76 0.364 28.3, 126.0 -0.6
NJL/Ms m 80.9 26.1   10 8.25 0.322 44.7, 126.0 -0.38
PGN2/Ms f 95.8 43.3   10 13.7 0.452 57.5, 172.0 0.8
PGN2/Ms m 93.4 14.3   10 4.53 0.154 79.2, 126.0 0.21
SWN/Ms f 99.0 6.31   10 1.99 0.0637 83.4, 109.0 1.03
SWN/Ms m 94.4 8.59   10 2.72 0.0911 80.0, 104.0 0.26


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
BALB/cAnN f 91.54 12.6068 116.3681 66.7119
BALB/cAnN m 67.32 12.6068 92.1481 42.4919
BFM/2Ms f 83.09 12.6068 107.9181 58.2619
BFM/2Ms m 87.59 12.6068 112.4181 62.7619
BLG2/Ms f 81.63 12.6068 106.4581 56.8019
BLG2/Ms m 94.3 12.6068 119.1281 69.4719
C57BL/6J f 66.95 12.6068 91.7781 42.1219
C57BL/6J m 61.43 12.6068 86.2581 36.6019
CAST/EiJ f 95.94 12.6068 120.7681 71.1119
CAST/EiJ m 94.42 12.6068 119.2481 69.5919
CHD/Ms f 81.91 12.6068 106.7381 57.0819
CHD/Ms m 80.18 12.6068 105.0081 55.3519
DBA/1J f 47.861 12.6068 72.6891 23.0329
DBA/1J m 54.7 12.6068 79.5281 29.8719
HMI/Ms f 83.09 12.6068 107.9181 58.2619
HMI/Ms m 134.18 12.6068 159.0081 109.3519
JF1/MsJ f 94.98 12.6068 119.8081 70.1519
JF1/MsJ m 100.72 12.6068 125.5481 75.8919
KJR/Ms f 98.26 12.6068 123.0881 73.4319
KJR/Ms m 83.5 12.6068 108.3281 58.6719
MSM/MsJ f 88.06 12.6068 112.8881 63.2319
MSM/MsJ m 117.83 12.6068 142.6581 93.0019
NJL/Ms f 76.09 12.6068 100.9181 51.2619
NJL/Ms m 80.93 12.6068 105.7581 56.1019
PGN2/Ms f 95.81 12.6068 120.6381 70.9819
PGN2/Ms m 93.37 12.6068 118.1981 68.5419
SWN/Ms f 99.01 12.6068 123.8381 74.1819
SWN/Ms m 94.38 12.6068 119.2081 69.5519


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
BALB/cAnN both 79.43 8.9143 96.9861 61.8739
BFM/2Ms both 85.34 8.9143 102.8961 67.7839
BLG2/Ms both 87.965 8.9143 105.5211 70.4089
C57BL/6J both 64.19 8.9143 81.7461 46.6339
CAST/EiJ both 95.18 8.9143 112.7361 77.6239
CHD/Ms both 81.045 8.9143 98.6011 63.4889
DBA/1J both 51.2805 8.9143 68.8366 33.7244
HMI/Ms both 108.635 8.9143 126.1911 91.0789
JF1/MsJ both 97.85 8.9143 115.4061 80.2939
KJR/Ms both 90.88 8.9143 108.4361 73.3239
MSM/MsJ both 102.945 8.9143 120.5011 85.3889
NJL/Ms both 78.51 8.9143 96.0661 60.9539
PGN2/Ms both 94.59 8.9143 112.1461 77.0339
SWN/Ms both 96.695 8.9143 114.2511 79.1389




GWAS analysis not available: Strain panel must be either Inbred, HMDP, BXD, BXH, CXB, or AXB/BXA