Project measure / variable:   Rhodes1   activity_control

ID, description, units MPD:34601   activity_control   locomotor activity   [km/d]  control  
exercise study
Data set, strains Rhodes1   inbred   12 strains     sex: both     age: 8-15wks
Procedure running wheel monitoring
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  STRAIN COMPARISON PLOT
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Rhodes1 - locomotor activity control



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested12 strains12 strains
Mean of the strain means0.262   km/d 0.231   km/d
Median of the strain means0.227   km/d 0.222   km/d
SD of the strain means± 0.113 ± 0.0768
Coefficient of variation (CV)0.432 0.333
Min–max range of strain means0.153   –   0.561   km/d 0.104   –   0.412   km/d
Mean sample size per strain4.0   mice 4.0   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 0.0227 0.0227 4.1581 0.0451
strain 11 0.7325 0.0666 12.2007 < 0.0001
sex:strain 11 0.0896 0.0081 1.4926 0.1532
Residuals 72 0.393 0.0055


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 0.153 0.0377   4 0.0188 0.247 0.097, 0.181 -0.96
129S1/SvImJ m 0.104 0.0397   4 0.0198 0.382 0.061, 0.157 -1.65
AKR/J f 0.22 0.0494   4 0.0247 0.224 0.187, 0.293 -0.37
AKR/J m 0.189 0.0181   4 0.00905 0.0957 0.164, 0.205 -0.55
B6129SF1/J f 0.219 0.0567   4 0.0283 0.258 0.173, 0.301 -0.38
B6129SF1/J m 0.17 0.0452   4 0.0226 0.267 0.127, 0.228 -0.79
B6D2F1/J f 0.244 0.0322   4 0.0161 0.132 0.206, 0.281 -0.16
B6D2F1/J m 0.285 0.0791   4 0.0395 0.278 0.183, 0.376 0.7
BALB/cByJ f 0.376 0.0147   4 0.00736 0.0392 0.357, 0.393 1.01
BALB/cByJ m 0.292 0.104   4 0.0518 0.355 0.231, 0.447 0.8
BTBR T+ Itpr3tf/J f 0.169 0.0106   4 0.00528 0.0624 0.156, 0.179 -0.82
BTBR T+ Itpr3tf/J m 0.186 0.0298   4 0.0149 0.16 0.157, 0.22 -0.58
C57BL/10J f 0.235 0.0924   4 0.0462 0.394 0.139, 0.361 -0.24
C57BL/10J m 0.25 0.108   4 0.0542 0.434 0.134, 0.385 0.25
C57BL/6J f 0.275 0.0414   4 0.0207 0.15 0.227, 0.328 0.12
C57BL/6J m 0.197 0.0257   4 0.0128 0.131 0.162, 0.224 -0.44
CAST/EiJ f 0.561 0.128   4 0.0638 0.227 0.395, 0.697 2.65
CAST/EiJ m 0.412 0.222   4 0.111 0.538 0.28, 0.742 2.36
DBA/2J f 0.171 0.0456   4 0.0228 0.267 0.131, 0.217 -0.8
DBA/2J m 0.243 0.0385   4 0.0193 0.158 0.205, 0.296 0.16
NOD/ShiLtJ f 0.306 0.0612   4 0.0306 0.2 0.22, 0.365 0.39
NOD/ShiLtJ m 0.22 0.0539   4 0.0269 0.245 0.169, 0.296 -0.14
SM/J f 0.21 0.0325   4 0.0163 0.155 0.177, 0.25 -0.46
SM/J m 0.223 0.0372   4 0.0186 0.167 0.183, 0.259 -0.1


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f 0.1525 0.0369 0.2261 0.0789
129S1/SvImJ m 0.1038 0.0369 0.1774 0.0301
AKR/J f 0.2203 0.0369 0.2939 0.1466
AKR/J m 0.189 0.0369 0.2626 0.1154
B6129SF1/J f 0.2193 0.0369 0.2929 0.1456
B6129SF1/J m 0.1698 0.0369 0.2434 0.0961
B6D2F1/J f 0.2443 0.0369 0.3179 0.1706
B6D2F1/J m 0.2848 0.0369 0.3584 0.2111
BALB/cByJ f 0.3758 0.0369 0.4494 0.3021
BALB/cByJ m 0.2923 0.0369 0.3659 0.2186
BTBR T+ Itpr3tf/J f 0.169 0.0369 0.2426 0.0954
BTBR T+ Itpr3tf/J m 0.1858 0.0369 0.2594 0.1121
C57BL/10J f 0.2348 0.0369 0.3084 0.1611
C57BL/10J m 0.25 0.0369 0.3236 0.1764
C57BL/6J f 0.2753 0.0369 0.3489 0.2016
C57BL/6J m 0.1965 0.0369 0.2701 0.1229
CAST/EiJ f 0.561 0.0369 0.6346 0.4874
CAST/EiJ m 0.4115 0.0369 0.4851 0.3379
DBA/2J f 0.1713 0.0369 0.2449 0.0976
DBA/2J m 0.2433 0.0369 0.3169 0.1696
NOD/ShiLtJ f 0.3058 0.0369 0.3794 0.2321
NOD/ShiLtJ m 0.2203 0.0369 0.2939 0.1466
SM/J f 0.2098 0.0369 0.2834 0.1361
SM/J m 0.223 0.0369 0.2966 0.1494


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ both 0.1281 0.0261 0.1802 0.0761
AKR/J both 0.2046 0.0261 0.2567 0.1526
B6129SF1/J both 0.1945 0.0261 0.2466 0.1424
B6D2F1/J both 0.2645 0.0261 0.3166 0.2124
BALB/cByJ both 0.334 0.0261 0.3861 0.2819
BTBR T+ Itpr3tf/J both 0.1774 0.0261 0.2294 0.1253
C57BL/10J both 0.2424 0.0261 0.2944 0.1903
C57BL/6J both 0.2359 0.0261 0.2879 0.1838
CAST/EiJ both 0.4862 0.0261 0.5383 0.4342
DBA/2J both 0.2073 0.0261 0.2593 0.1552
NOD/ShiLtJ both 0.263 0.0261 0.3151 0.2109
SM/J both 0.2164 0.0261 0.2684 0.1643




  GWAS USING LINEAR MIXED MODELS