Project measure / variable:   Berndt1   airway_res_mch3

ID, description, units MPD:34212   airway_res_mch3   airway resistance (H2O pressure)   [cm/mL/s]  MCh challenge 3 mg/mL  
methacholine study
Data set, strains Berndt1   inbred   37 strains     sex: both     age: 9-12wks
Procedure ventilator
Ontology mappings

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  STRAIN COMPARISON PLOT
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Berndt1 - airway resistance (H2O pressure) MCh challenge 3 mg/mL



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested36 strains33 strains
Mean of the strain means0.660   cm/mL/s 0.746   cm/mL/s
Median of the strain means0.679   cm/mL/s 0.703   cm/mL/s
SD of the strain means± 0.193 ± 0.203
Coefficient of variation (CV)0.293 0.273
Min–max range of strain means0.374   –   1.11   cm/mL/s 0.412   –   1.22   cm/mL/s
Mean sample size per strain8.6   mice 9.3   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 0.9044 0.9044 20.1632 < 0.0001
strain 31 17.8674 0.5764 12.8502 < 0.0001
sex:strain 31 4.2612 0.1375 3.0647 < 0.0001
Residuals 509 22.8301 0.0449


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
Select table page:
Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 0.379 0.0787   9 0.0262 0.208 0.29, 0.52 -1.45
129S1/SvImJ m 0.48 0.184   8 0.0649 0.383 0.36, 0.92 -1.31
A/J f 0.97 0.284   10 0.0897 0.292 0.61, 1.53 1.61
A/J m 1.22 0.311   9 0.104 0.254 0.64, 1.59 2.33
AKR/J f 0.702 0.172   9 0.0574 0.245 0.38, 0.98 0.22
AKR/J m 1.09 0.308   8 0.109 0.282 0.55, 1.4 1.69
BALB/cByJ f 0.63 0.146   8 0.0515 0.231 0.47, 0.94 -0.15
BALB/cByJ m 0.858 0.389   8 0.138 0.454 0.52, 1.66 0.55
BALB/cJ f 0.674 0.136   8 0.0481 0.202 0.5, 0.9 0.07
BALB/cJ m 0.881 0.229   10 0.0724 0.26 0.66, 1.43 0.66
BPN/3J f 0.441 0.122   8 0.043 0.276 0.29, 0.63 -1.13
BTBR T+ Itpr3tf/J f 0.68 0.213   10 0.0675 0.314 0.33, 1.01 0.1
BTBR T+ Itpr3tf/J m 0.77 0.135   10 0.0428 0.176 0.59, 1.01 0.12
BUB/BnJ f 0.91 0.255   9 0.0849 0.28 0.61, 1.4 1.29
BUB/BnJ m 0.677 0.118   10 0.0374 0.175 0.48, 0.87 -0.34
C3H/HeJ f 0.772 0.218   10 0.0689 0.282 0.47, 1.17 0.58
C3H/HeJ m 0.77 0.158   9 0.0528 0.206 0.62, 1.08 0.12
C57BL/10J f 0.428 0.092   9 0.0307 0.215 0.34, 0.64 -1.2
C57BL/10J m 0.643 0.0815   10 0.0258 0.127 0.54, 0.78 -0.51
C57BL/6J f 0.43 0.148   8 0.0522 0.344 0.26, 0.65 -1.19
C57BL/6J m 0.777 0.23   8 0.0814 0.296 0.44, 1.05 0.15
C57BLKS/J f 0.387 0.114   9 0.0382 0.296 0.27, 0.66 -1.41
C57BLKS/J m 0.672 0.227   12 0.0655 0.338 0.39, 1.04 -0.36
C57BR/cdJ f 0.679 0.19   7 0.0718 0.28 0.38, 0.92 0.1
C57BR/cdJ m 0.743 0.222   10 0.07 0.298 0.53, 1.3 -0.01
C57L/J f 0.708 0.239   6 0.0978 0.338 0.42, 1.0 0.25
C57L/J m 0.629 0.141   10 0.0446 0.224 0.41, 0.83 -0.57
CBA/J f 0.865 0.249   8 0.0881 0.288 0.59, 1.29 1.06
CBA/J m 0.653 0.0914   10 0.0289 0.14 0.47, 0.76 -0.46
CE/J f 0.744 0.309   9 0.103 0.415 0.43, 1.47 0.44
CE/J m 0.738 0.144   9 0.0481 0.196 0.53, 0.94 -0.04
DBA/1J f 0.698 0.232   9 0.0775 0.333 0.44, 1.2 0.2
DBA/1J m 0.707 0.233   10 0.0737 0.33 0.37, 1.14 -0.19
DBA/2J f 0.534 0.0919   10 0.0291 0.172 0.37, 0.65 -0.65
DBA/2J m 0.781 0.144   10 0.0454 0.184 0.57, 1.1 0.17
FVB/NJ f 0.817 0.305   10 0.0963 0.373 0.4, 1.49 0.81
FVB/NJ m 0.611 0.317   10 0.1 0.52 0.21, 1.17 -0.66
I/LnJ f 1.11 0.265   9 0.0885 0.239 0.56, 1.45 2.33
I/LnJ m 1.07 0.368   8 0.13 0.343 0.55, 1.6 1.59
KK/HlJ f 1.04 0.305   9 0.102 0.293 0.48, 1.42 1.97
KK/HlJ m 1.09 0.263   10 0.0833 0.241 0.64, 1.56 1.69
LG/J f 0.439 0.064   10 0.0202 0.146 0.35, 0.54 -1.14
LG/J m 0.498 0.107   10 0.0338 0.215 0.34, 0.7 -1.22
LP/J f 0.374 0.06   9 0.02 0.16 0.31, 0.5 -1.48
LP/J m 0.612 0.0757   10 0.0239 0.124 0.5, 0.74 -0.66
MA/MyJ f 0.662 0.0861   9 0.0287 0.13 0.56, 0.79 0.01
MRL/MpJ f 0.708 0.225   9 0.0748 0.317 0.45, 1.09 0.25
MRL/MpJ m 0.69 0.203   9 0.0675 0.294 0.46, 1.18 -0.27
NOD/ShiLtJ f 0.656 0.271   9 0.0902 0.413 0.31, 1.25 -0.02
NOD/ShiLtJ m 0.956 0.363   9 0.121 0.38 0.68, 1.85 1.03
NON/ShiLtJ f 0.866 0.281   7 0.106 0.324 0.62, 1.47 1.07
NON/ShiLtJ m 0.703 0.162   7 0.0611 0.23 0.54, 0.93 -0.21
NZB/BlNJ m 0.444 0.119   10 0.0376 0.268 0.26, 0.66 -1.48
NZO/HlLtJ f 0.717 0.137   9 0.0455 0.191 0.48, 0.96 0.3
NZW/LacJ f 0.427 0.0936   8 0.0331 0.219 0.27, 0.53 -1.2
NZW/LacJ m 0.412 0.0432   10 0.0136 0.105 0.36, 0.49 -1.64
P/J f 0.629 0.152   7 0.0575 0.242 0.43, 0.92 -0.16
P/J m 0.726 0.327   8 0.116 0.451 0.47, 1.38 -0.1
PL/J f 0.752 0.182   9 0.0607 0.242 0.53, 1.09 0.48
PL/J m 1.17 0.138   8 0.0486 0.118 1.04, 1.47 2.09
PWD/PhJ f 0.525 0.135   6 0.0551 0.257 0.3, 0.69 -0.7
RIIIS/J f 0.79 0.356   6 0.145 0.451 0.39, 1.31 0.67
RIIIS/J m 0.688 0.202   9 0.0674 0.294 0.4, 1.11 -0.28
SJL/J f 0.47 0.0974   8 0.0344 0.207 0.37, 0.65 -0.98
SJL/J m 0.659 0.15   9 0.05 0.227 0.48, 0.89 -0.43
SM/J f 0.733 0.269   10 0.085 0.367 0.48, 1.28 0.38
SM/J m 0.703 0.144   8 0.0511 0.206 0.55, 0.96 -0.21
SWR/J f 0.404 0.0835   9 0.0278 0.207 0.28, 0.52 -1.32
SWR/J m 0.491 0.13   10 0.0411 0.265 0.38, 0.79 -1.25


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f 0.3789 0.0706 0.5176 0.2402
129S1/SvImJ m 0.48 0.0749 0.6271 0.3329
A/J f 0.97 0.067 1.1016 0.8384
A/J m 1.2244 0.0706 1.3631 1.0858
AKR/J f 0.7022 0.0706 0.8409 0.5635
AKR/J m 1.095 0.0749 1.2421 0.9479
BALB/cByJ f 0.63 0.0749 0.7771 0.4829
BALB/cByJ m 0.8575 0.0749 1.0046 0.7104
BALB/cJ f 0.6738 0.0749 0.8209 0.5266
BALB/cJ m 0.881 0.067 1.0126 0.7494
BTBR T+ Itpr3tf/J f 0.68 0.067 0.8116 0.5484
BTBR T+ Itpr3tf/J m 0.77 0.067 0.9016 0.6384
BUB/BnJ f 0.91 0.0706 1.0487 0.7713
BUB/BnJ m 0.677 0.067 0.8086 0.5454
C3H/HeJ f 0.772 0.067 0.9036 0.6404
C3H/HeJ m 0.77 0.0706 0.9087 0.6313
C57BL/10J f 0.4278 0.0706 0.5665 0.2891
C57BL/10J m 0.643 0.067 0.7746 0.5114
C57BL/6J f 0.43 0.0749 0.5771 0.2829
C57BL/6J m 0.7775 0.0749 0.9246 0.6304
C57BLKS/J f 0.3867 0.0706 0.5254 0.248
C57BLKS/J m 0.6717 0.0611 0.7918 0.5516
C57BR/cdJ f 0.6786 0.08 0.8358 0.5213
C57BR/cdJ m 0.743 0.067 0.8746 0.6114
C57L/J f 0.7083 0.0865 0.8782 0.5385
C57L/J m 0.629 0.067 0.7606 0.4974
CBA/J f 0.865 0.0749 1.0121 0.7179
CBA/J m 0.653 0.067 0.7846 0.5214
CE/J f 0.7444 0.0706 0.8831 0.6058
CE/J m 0.7378 0.0706 0.8765 0.5991
DBA/1J f 0.6978 0.0706 0.8365 0.5591
DBA/1J m 0.707 0.067 0.8386 0.5754
DBA/2J f 0.534 0.067 0.6656 0.4024
DBA/2J m 0.781 0.067 0.9126 0.6494
FVB/NJ f 0.817 0.067 0.9486 0.6854
FVB/NJ m 0.611 0.067 0.7426 0.4794
I/LnJ f 1.11 0.0706 1.2487 0.9713
I/LnJ m 1.0725 0.0749 1.2196 0.9254
KK/HlJ f 1.0422 0.0706 1.1809 0.9035
KK/HlJ m 1.092 0.067 1.2236 0.9604
LG/J f 0.439 0.067 0.5706 0.3074
LG/J m 0.498 0.067 0.6296 0.3664
LP/J f 0.3744 0.0706 0.5131 0.2358
LP/J m 0.612 0.067 0.7436 0.4804
MRL/MpJ f 0.7078 0.0706 0.8465 0.5691
MRL/MpJ m 0.69 0.0706 0.8287 0.5513
NOD/ShiLtJ f 0.6556 0.0706 0.7942 0.5169
NOD/ShiLtJ m 0.9556 0.0706 1.0942 0.8169
NON/ShiLtJ f 0.8657 0.08 1.023 0.7085
NON/ShiLtJ m 0.7029 0.08 0.8601 0.5456
NZW/LacJ f 0.4275 0.0749 0.5746 0.2804
NZW/LacJ m 0.412 0.067 0.5436 0.2804
P/J f 0.6286 0.08 0.7858 0.4713
P/J m 0.7262 0.0749 0.8734 0.5791
PL/J f 0.7522 0.0706 0.8909 0.6135
PL/J m 1.165 0.0749 1.3121 1.0179
RIIIS/J f 0.79 0.0865 0.9599 0.6201
RIIIS/J m 0.6878 0.0706 0.8265 0.5491
SJL/J f 0.47 0.0749 0.6171 0.3229
SJL/J m 0.6589 0.0706 0.7976 0.5202
SM/J f 0.733 0.067 0.8646 0.6014
SM/J m 0.7025 0.0749 0.8496 0.5554
SWR/J f 0.4044 0.0706 0.5431 0.2658
SWR/J m 0.491 0.067 0.6226 0.3594


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ both 0.4294 0.0515 0.5305 0.3284
A/J both 1.0972 0.0487 1.1928 1.0016
AKR/J both 0.8986 0.0515 0.9997 0.7975
BALB/cByJ both 0.7437 0.0529 0.8478 0.6397
BALB/cJ both 0.7774 0.0502 0.8761 0.6787
BTBR T+ Itpr3tf/J both 0.725 0.0474 0.818 0.632
BUB/BnJ both 0.7935 0.0487 0.8891 0.6979
C3H/HeJ both 0.771 0.0487 0.8666 0.6754
C57BL/10J both 0.5354 0.0487 0.631 0.4398
C57BL/6J both 0.6037 0.0529 0.7078 0.4997
C57BLKS/J both 0.5292 0.0467 0.6209 0.4374
C57BR/cdJ both 0.7108 0.0522 0.8133 0.6083
C57L/J both 0.6687 0.0547 0.7761 0.5612
CBA/J both 0.759 0.0502 0.8577 0.6603
CE/J both 0.7411 0.0499 0.8392 0.643
DBA/1J both 0.7024 0.0487 0.798 0.6068
DBA/2J both 0.6575 0.0474 0.7505 0.5645
FVB/NJ both 0.714 0.0474 0.807 0.621
I/LnJ both 1.0913 0.0515 1.1923 0.9902
KK/HlJ both 1.0671 0.0487 1.1627 0.9715
LG/J both 0.4685 0.0474 0.5615 0.3755
LP/J both 0.4932 0.0487 0.5888 0.3976
MRL/MpJ both 0.6989 0.0499 0.797 0.6008
NOD/ShiLtJ both 0.8056 0.0499 0.9036 0.7075
NON/ShiLtJ both 0.7843 0.0566 0.8955 0.6731
NZW/LacJ both 0.4198 0.0502 0.5184 0.3211
P/J both 0.6774 0.0548 0.7851 0.5697
PL/J both 0.9586 0.0515 1.0597 0.8575
RIIIS/J both 0.7389 0.0558 0.8485 0.6292
SJL/J both 0.5644 0.0515 0.6655 0.4634
SM/J both 0.7178 0.0502 0.8164 0.6191
SWR/J both 0.4477 0.0487 0.5433 0.3521




  GWAS USING LINEAR MIXED MODELS