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Project measure / variable:   Shockley1   TG_fat

ID, description, units MPD:33439   TG_fat   triglycerides (TG, 5h fast)   [mg/dL]  high-fat diet  
high-fat diet study
Data set, strains Shockley1   inbred   10 strains     sex: both     age: 10-13wks
Procedure lipid profile
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  STRAIN COMPARISON PLOT
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Shockley1 - triglycerides (TG, 5h fast) high-fat diet



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested10 strains10 strains
Mean of the strain means63.0   mg/dL 69.3   mg/dL
Median of the strain means57.5   mg/dL 58.0   mg/dL
SD of the strain means± 22.9 ± 28.9
Coefficient of variation (CV)0.364 0.418
Min–max range of strain means32.4   –   115   mg/dL 45.2   –   137   mg/dL
Mean sample size per strain4.9   mice 4.9   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 1094.8167 1094.8167 3.0542 0.0846
strain 9 51131.7825 5681.3092 15.8494 < 0.0001
sex:strain 9 9294.8604 1032.7623 2.8811 0.0056
Residuals 75 26884.2667 358.4569


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 62.0 11.6   4 5.82 0.188 48.0, 75.0 -0.05
129S1/SvImJ m 85.8 20.7   5 9.26 0.241 61.0, 118.0 0.57
A/J f 58.5 10.4   4 5.19 0.177 46.0, 68.0 -0.2
A/J m 48.2 10.7   5 4.79 0.222 39.0, 65.0 -0.73
BALB/cJ f 55.8 15.4   5 6.89 0.276 32.0, 73.0 -0.32
BALB/cJ m 49.6 8.62   5 3.85 0.174 42.0, 63.0 -0.68
C3H/HeJ f 49.4 6.43   5 2.87 0.13 39.0, 55.0 -0.6
C3H/HeJ m 61.3 15.7   3 9.06 0.256 49.0, 79.0 -0.28
C57BL/6J f 51.0 6.04   5 2.7 0.118 45.0, 60.0 -0.53
C57BL/6J m 45.2 3.83   5 1.71 0.0848 43.0, 52.0 -0.83
DBA/2J f 88.4 45.4   5 20.3 0.513 44.0, 154.0 1.11
DBA/2J m 137.0 18.1   5 8.09 0.132 110.0, 155.0 2.34
I/LnJ f 32.4 9.76   5 4.37 0.301 18.0, 45.0 -1.34
I/LnJ m 54.6 23.1   5 10.3 0.424 36.0, 90.0 -0.51
MRL/MpJ-Faslpr/J f 115.0 37.5   5 16.8 0.327 66.0, 163.0 2.27
MRL/MpJ-Faslpr/J m 95.2 22.2   5 9.94 0.233 66.0, 125.0 0.9
NZB/BlNJ f 61.4 7.96   5 3.56 0.13 48.0, 69.0 -0.07
NZB/BlNJ m 52.5 7.77   4 3.88 0.148 47.0, 64.0 -0.58
SM/J f 56.6 18.0   5 8.05 0.318 39.0, 87.0 -0.28
SM/J m 63.2 10.9   5 4.87 0.172 52.0, 81.0 -0.21


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f 62.0 9.4665 80.8582 43.1418
129S1/SvImJ m 85.8 8.4671 102.6673 68.9327
A/J f 58.5 9.4665 77.3582 39.6418
A/J m 48.2 8.4671 65.0673 31.3327
BALB/cJ f 55.8 8.4671 72.6673 38.9327
BALB/cJ m 49.6 8.4671 66.4673 32.7327
C3H/HeJ f 49.4 8.4671 66.2673 32.5327
C3H/HeJ m 61.3333 10.9309 83.1089 39.5578
C57BL/6J f 51.0 8.4671 67.8673 34.1327
C57BL/6J m 45.2 8.4671 62.0673 28.3327
DBA/2J f 88.4 8.4671 105.2673 71.5327
DBA/2J m 136.6 8.4671 153.4673 119.7327
I/LnJ f 32.4 8.4671 49.2673 15.5327
I/LnJ m 54.6 8.4671 71.4673 37.7327
MRL/MpJ-Faslpr/J f 114.6 8.4671 131.4673 97.7327
MRL/MpJ-Faslpr/J m 95.2 8.4671 112.0673 78.3327
NZB/BlNJ f 61.4 8.4671 78.2673 44.5327
NZB/BlNJ m 52.5 9.4665 71.3582 33.6418
SM/J f 56.6 8.4671 73.4673 39.7327
SM/J m 63.2 8.4671 80.0673 46.3327


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ both 73.9 6.3503 86.5505 61.2495
A/J both 53.35 6.3503 66.0005 40.6995
BALB/cJ both 52.7 5.9871 64.627 40.773
C3H/HeJ both 55.3667 6.9133 69.1387 41.5946
C57BL/6J both 48.1 5.9871 60.027 36.173
DBA/2J both 112.5 5.9871 124.427 100.573
I/LnJ both 43.5 5.9871 55.427 31.573
MRL/MpJ-Faslpr/J both 104.9 5.9871 116.827 92.973
NZB/BlNJ both 56.95 6.3503 69.6005 44.2995
SM/J both 59.9 5.9871 71.827 47.973




  GWAS USING LINEAR MIXED MODELS