Project measure / variable:   Shockley1   CA_fat

ID, description, units MPD:33433   CA_fat   calcium (serum Ca)   [mg/dL]  high-fat diet  
high-fat diet study
Data set, strains Shockley1   inbred   10 strains     sex: both     age: 10-13wks
Procedure metabolic panel
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  STRAIN COMPARISON PLOT
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Shockley1 - calcium (serum Ca) high-fat diet



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested10 strains10 strains
Mean of the strain means3.35   mg/dL 3.31   mg/dL
Median of the strain means3.42   mg/dL 3.37   mg/dL
SD of the strain means± 0.590 ± 0.627
Coefficient of variation (CV)0.176 0.189
Min–max range of strain means2.40   –   4.10   mg/dL 2.28   –   4.16   mg/dL
Mean sample size per strain4.0   mice 4.4   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 0.0341 0.0341 0.1045 0.7479
strain 7 16.5328 2.3618 7.2302 < 0.0001
sex:strain 7 3.1337 0.4477 1.3705 0.238
Residuals 51 16.6597 0.3267


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 3.55 0.265   4 0.132 0.0745 3.2, 3.8 0.35
129S1/SvImJ m 4.08 0.396   5 0.177 0.0971 3.7, 4.7 1.22
A/J f 3.12 0.435   4 0.217 0.139 2.5, 3.5 -0.38
A/J m 3.34 0.305   5 0.136 0.0913 2.9, 3.7 0.04
BALB/cJ f 3.98 0.335   5 0.15 0.0841 3.6, 4.4 1.08
BALB/cJ m 4.16 0.82   5 0.367 0.197 3.2, 5.1 1.35
C3H/HeJ f 3.98 0.455   5 0.203 0.114 3.5, 4.5 1.08
C3H/HeJ m 3.4 0.0   1   0.0 0.0 3.4, 3.4 0.14
C57BL/6J f 2.4 0.436   3 0.252 0.182 1.9, 2.7 -1.6
C57BL/6J m 2.85 0.0577   4 0.0289 0.0203 2.8, 2.9 -0.74
DBA/2J f 3.47 0.877   4 0.439 0.252 2.2, 4.2 0.21
DBA/2J m 2.72 1.21   5 0.541 0.445 1.5, 4.3 -0.95
I/LnJ f 2.8 0.0   1   0.0 0.0 2.8, 2.8 -0.92
I/LnJ m 2.28 0.179   5 0.08 0.0785 2.0, 2.5 -1.65
MRL/MpJ-Faslpr/J f 3.38 0.634   5 0.284 0.188 2.6, 4.0 0.06
MRL/MpJ-Faslpr/J m 3.86 0.297   5 0.133 0.0769 3.4, 4.2 0.87
NZB/BlNJ f 4.1 0.271   4 0.135 0.066 3.7, 4.3 1.28
NZB/BlNJ m 3.6 0.566   2   0.4 0.157 3.2, 4.0 0.46
SM/J f 2.67 0.115   3 0.0667 0.0433 2.6, 2.8 -1.14
SM/J m 2.85 0.473   4 0.236 0.166 2.2, 3.2 -0.74


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f 3.55 0.2858 4.1237 2.9763
129S1/SvImJ m 4.08 0.2556 4.5931 3.5669
A/J f 3.125 0.2858 3.6987 2.5513
A/J m 3.34 0.2556 3.8531 2.8269
BALB/cJ f 3.98 0.2556 4.4931 3.4669
BALB/cJ m 4.16 0.2556 4.6731 3.6469
C57BL/6J f 2.4 0.33 3.0625 1.7375
C57BL/6J m 2.85 0.2858 3.4237 2.2763
DBA/2J f 3.475 0.2858 4.0487 2.9013
DBA/2J m 2.72 0.2556 3.2331 2.2069
MRL/MpJ-Faslpr/J f 3.38 0.2556 3.8931 2.8669
MRL/MpJ-Faslpr/J m 3.86 0.2556 4.3731 3.3469
NZB/BlNJ f 4.1 0.2858 4.6737 3.5263
NZB/BlNJ m 3.6 0.4041 4.4113 2.7887
SM/J f 2.6667 0.33 3.3291 2.0042
SM/J m 2.85 0.2858 3.4237 2.2763


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ both 3.815 0.1917 4.1999 3.4301
A/J both 3.2325 0.1917 3.6174 2.8476
BALB/cJ both 4.07 0.1807 4.4328 3.7072
C57BL/6J both 2.625 0.2183 3.0632 2.1868
DBA/2J both 3.0975 0.1917 3.4824 2.7126
MRL/MpJ-Faslpr/J both 3.62 0.1807 3.9828 3.2572
NZB/BlNJ both 3.85 0.2475 4.3468 3.3532
SM/J both 2.7583 0.2183 3.1965 2.3202




  GWAS USING LINEAR MIXED MODELS