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Project measure / variable:   Maurer1   Parea_at

ID, description, units MPD:33254   Parea_at   area of P-wave   [ms*mV]  atenolol 10mg  
atenolol, isoproterenol study
Data set, strains Maurer1   inbred   22 strains     sex: m     age: 7-13wks
Procedure ECG
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  STRAIN COMPARISON PLOT
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Maurer1 - area of P-wave atenolol 10mg



  MEASURE SUMMARY
Measure Summary Male
Number of strains tested22 strains
Mean of the strain means0.584   ms*mV
Median of the strain means0.579   ms*mV
SD of the strain means± 0.176
Coefficient of variation (CV)0.301
Min–max range of strain means0.267   –   1.05   ms*mV
Mean sample size per strain8.8   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
strain 21 4.9291 0.2347 11.3202 < 0.0001
Residuals 170 3.5249 0.0207


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ m 0.672 0.199   13 0.0552 0.297 0.38, 1.09 0.5
A/J m 0.597 0.236   3 0.136 0.396 0.33, 0.78 0.07
AKR/J m 0.551 0.178   7 0.0671 0.322 0.33, 0.8 -0.19
BALB/cByJ m 0.69 0.099   2   0.07 0.143 0.62, 0.76 0.6
BALB/cJ m 0.534 0.0762   10 0.0241 0.143 0.45, 0.68 -0.28
BTBR T+ Itpr3tf/J m 0.838 0.166   9 0.0554 0.198 0.62, 1.08 1.44
C3H/HeJ m 0.7 0.118   8 0.0417 0.168 0.49, 0.87 0.66
C57BL/6J m 0.35 0.128   9 0.0427 0.366 0.13, 0.54 -1.33
C57BLKS/J m 0.492 0.149   9 0.0497 0.303 0.22, 0.69 -0.52
C58/J m 0.267 0.112   12 0.0323 0.42 0.1, 0.47 -1.8
CBA/J m 0.358 0.0594   2   0.042 0.166 0.316, 0.4 -1.28
DBA/2J m 1.05 0.158   5 0.0706 0.15 0.788, 1.21 2.65
FVB/NJ m 0.56 0.0702   14 0.0188 0.125 0.46, 0.69 -0.14
I/LnJ m 0.746 0.129   9 0.043 0.173 0.57, 0.99 0.92
KK/HlJ m 0.356 0.154   9 0.0512 0.432 0.07, 0.64 -1.3
LP/J m 0.63 0.259   10 0.082 0.412 0.35, 1.14 0.26
NOD/ShiLtJ m 0.633 0.136   10 0.043 0.215 0.52, 0.99 0.28
NZB/BlNJ m 0.501 0.0875   9 0.0292 0.175 0.4, 0.67 -0.47
PL/J m 0.524 0.0901   10 0.0285 0.172 0.3, 0.61 -0.34
SJL/J m 0.602 0.131   9 0.0438 0.218 0.4, 0.77 0.1
SM/J m 0.703 0.118   12 0.034 0.168 0.46, 0.88 0.68
SWR/J m 0.492 0.153   11 0.0462 0.312 0.28, 0.72 -0.52


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ m 0.6715 0.0399 0.7504 0.5927
A/J m 0.5967 0.0831 0.7608 0.4326
AKR/J m 0.5514 0.0544 0.6589 0.444
BALB/cByJ m 0.69 0.1018 0.891 0.489
BALB/cJ m 0.534 0.0455 0.6239 0.4441
BTBR T+ Itpr3tf/J m 0.8378 0.048 0.9325 0.743
C3H/HeJ m 0.7 0.0509 0.8005 0.5995
C57BL/6J m 0.35 0.048 0.4447 0.2553
C57BLKS/J m 0.4922 0.048 0.587 0.3975
C58/J m 0.2667 0.0416 0.3487 0.1846
CBA/J m 0.358 0.1018 0.559 0.157
DBA/2J m 1.0536 0.0644 1.1807 0.9265
FVB/NJ m 0.56 0.0385 0.636 0.484
I/LnJ m 0.7456 0.048 0.8403 0.6508
KK/HlJ m 0.3556 0.048 0.4503 0.2608
LP/J m 0.63 0.0455 0.7199 0.5401
NOD/ShiLtJ m 0.633 0.0455 0.7229 0.5431
NZB/BlNJ m 0.5011 0.048 0.5959 0.4064
PL/J m 0.524 0.0455 0.6139 0.4341
SJL/J m 0.6023 0.048 0.6971 0.5076
SM/J m 0.7025 0.0416 0.7846 0.6204
SWR/J m 0.4918 0.0434 0.5775 0.4061




  GWAS USING LINEAR MIXED MODELS