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Project measure / variable:   Maurer1   ST_ctrl

ID, description, units MPD:33249   ST_ctrl   interval ST   [ms]  control  
atenolol, isoproterenol study
Data set, strains Maurer1   inbred   23 strains     sex: m     age: 7-13wks
Procedure ECG
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  STRAIN COMPARISON PLOT
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Maurer1 - interval ST control



  MEASURE SUMMARY
Measure Summary Male
Number of strains tested23 strains
Mean of the strain means42.8   ms
Median of the strain means42.2   ms
SD of the strain means± 5.66
Coefficient of variation (CV)0.132
Min–max range of strain means31.9   –   54.5   ms
Mean sample size per strain9.7   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
strain 22 6445.148 292.9613 3.0014 < 0.0001
Residuals 201 19619.5025 97.6095


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ m 43.8 5.68   13 1.57 0.13 34.6, 53.1 0.18
A/J m 33.4 11.7   11 3.51 0.349 7.41, 46.7 -1.66
AKR/J m 47.5 6.05   8 2.14 0.127 40.0, 58.1 0.84
BALB/cByJ m 48.5 4.37   9 1.46 0.0901 41.4, 55.2 1.01
BALB/cJ m 40.1 5.19   10 1.64 0.129 30.0, 49.6 -0.47
BTBR T+ Itpr3tf/J m 44.0 3.97   10 1.26 0.0903 37.3, 51.8 0.22
C3H/HeJ m 39.5 9.51   10 3.01 0.241 16.0, 49.1 -0.58
C3H/HeOuJ m 47.7 4.02   9 1.34 0.0844 39.7, 52.5 0.87
C57BL/6J m 40.0 3.31   9 1.1 0.0827 32.6, 44.0 -0.49
C57BLKS/J m 48.3 4.0   10 1.26 0.0827 42.2, 55.4 0.98
C58/J m 44.0 7.94   12 2.29 0.181 33.5, 60.1 0.22
CBA/J m 41.0 8.5   8 3.0 0.207 22.8, 52.5 -0.31
DBA/2J m 50.2 14.9   6 6.07 0.296 29.0, 64.8 1.31
FVB/NJ m 41.5 4.58   12 1.32 0.11 34.7, 50.8 -0.22
I/LnJ m 54.5 36.6   9 12.2 0.672 9.88, 119.0 2.08
KK/HlJ m 43.0 3.08   10 0.973 0.0715 36.4, 46.5 0.04
LP/J m 37.4 2.48   8 0.877 0.0663 32.5, 40.8 -0.95
NOD/ShiLtJ m 41.9 3.95   9 1.32 0.0943 35.0, 46.8 -0.15
NZB/BlNJ m 33.2 4.71   8 1.67 0.142 25.1, 37.8 -1.69
PL/J m 41.2 7.65   10 2.42 0.186 23.9, 50.4 -0.28
SJL/J m 31.9 1.87   9 0.623 0.0585 29.1, 35.0 -1.92
SM/J m 48.8 9.45   14 2.53 0.194 35.6, 66.6 1.07
SWR/J m 42.2 7.65   10 2.42 0.181 33.5, 54.9 -0.1


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ m 43.7692 2.7401 49.1724 38.3661
A/J m 33.3645 2.9789 39.2384 27.4907
AKR/J m 47.525 3.493 54.4127 40.6373
BALB/cByJ m 48.5222 3.2933 55.016 42.0285
BALB/cJ m 40.14 3.1243 46.3005 33.9795
BTBR T+ Itpr3tf/J m 43.97 3.1243 50.1305 37.8095
C3H/HeJ m 39.49 3.1243 45.6505 33.3295
C3H/HeOuJ m 47.7 3.2933 54.1938 41.2062
C57BL/6J m 40.0444 3.2933 46.5382 33.5507
C57BLKS/J m 48.33 3.1243 54.4905 42.1695
C58/J m 43.975 2.852 49.5988 38.3512
CBA/J m 41.05 3.493 47.9377 34.1623
DBA/2J m 50.25 4.0334 58.2032 42.2968
FVB/NJ m 41.475 2.852 47.0988 35.8512
I/LnJ m 54.4756 3.2933 60.9693 47.9818
KK/HlJ m 43.03 3.1243 49.1905 36.8695
LP/J m 37.425 3.493 44.3127 30.5373
NOD/ShiLtJ m 41.9222 3.2933 48.416 35.4285
NZB/BlNJ m 33.2 3.493 40.0877 26.3123
PL/J m 41.19 3.1243 47.3505 35.0295
SJL/J m 31.9333 3.2933 38.4271 25.4396
SM/J m 48.8143 2.6405 54.0209 43.6077
SWR/J m 42.24 3.1243 48.4005 36.0795




  GWAS USING LINEAR MIXED MODELS