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Project measure / variable:   Maurer1   QRS_ctrl

ID, description, units MPD:33241   QRS_ctrl   interval QRS   [ms]  control  
atenolol, isoproterenol study
Data set, strains Maurer1   inbred   23 strains     sex: m     age: 7-13wks
Procedure ECG
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  STRAIN COMPARISON PLOT
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Maurer1 - interval QRS control



  MEASURE SUMMARY
Measure Summary Male
Number of strains tested23 strains
Mean of the strain means12.6   ms
Median of the strain means12.8   ms
SD of the strain means± 1.44
Coefficient of variation (CV)0.114
Min–max range of strain means9.40   –   14.7   ms
Mean sample size per strain9.7   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
strain 22 419.0856 19.0493 7.0375 < 0.0001
Residuals 201 544.0724 2.7068


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ m 14.6 2.05   13 0.568 0.141 12.2, 18.6 1.38
A/J m 12.9 1.51   11 0.455 0.117 11.0, 15.6 0.2
AKR/J m 11.3 1.18   8 0.416 0.104 9.56, 13.2 -0.92
BALB/cByJ m 14.7 1.3   9 0.433 0.0882 13.7, 17.0 1.45
BALB/cJ m 12.8 1.73   10 0.546 0.135 10.1, 15.3 0.13
BTBR T+ Itpr3tf/J m 14.2 1.04   10 0.328 0.0728 12.7, 15.2 1.1
C3H/HeJ m 12.1 1.11   10 0.352 0.092 9.21, 13.0 -0.36
C3H/HeOuJ m 10.9 1.24   9 0.413 0.113 9.0, 12.7 -1.2
C57BL/6J m 13.2 1.04   9 0.347 0.0789 11.6, 15.0 0.41
C57BLKS/J m 12.1 1.51   10 0.478 0.125 10.4, 14.2 -0.36
C58/J m 13.4 1.61   12 0.465 0.12 11.5, 17.2 0.55
CBA/J m 10.3 1.9   8 0.672 0.184 7.15, 13.3 -1.61
DBA/2J m 11.9 0.713   6 0.291 0.0599 11.0, 13.0 -0.5
FVB/NJ m 12.7 0.862   12 0.249 0.068 10.4, 13.8 0.06
I/LnJ m 9.4 1.28   9 0.428 0.137 7.46, 11.3 -2.24
KK/HlJ m 13.8 1.42   10 0.448 0.103 12.3, 15.9 0.82
LP/J m 13.3 1.56   8 0.551 0.117 11.3, 16.3 0.48
NOD/ShiLtJ m 11.5 1.66   9 0.552 0.144 9.78, 15.0 -0.78
NZB/BlNJ m 14.6 3.61   8 1.28 0.247 9.6, 20.8 1.38
PL/J m 13.8 2.52   10 0.798 0.183 10.1, 19.0 0.82
SJL/J m 10.9 0.973   9 0.324 0.0896 9.81, 12.2 -1.2
SM/J m 13.4 1.86   14 0.498 0.139 9.79, 15.9 0.55
SWR/J m 12.4 1.59   10 0.503 0.129 10.3, 14.9 -0.15


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ m 14.5615 0.4563 15.4613 13.6618
A/J m 12.9091 0.4961 13.8872 11.9309
AKR/J m 11.3075 0.5817 12.4545 10.1605
BALB/cByJ m 14.7222 0.5484 15.8036 13.6408
BALB/cJ m 12.8 0.5203 13.8259 11.7741
BTBR T+ Itpr3tf/J m 14.24 0.5203 15.2659 13.2141
C3H/HeJ m 12.091 0.5203 13.1169 11.0651
C3H/HeOuJ m 10.9211 0.5484 12.0025 9.8397
C57BL/6J m 13.2 0.5484 14.2814 12.1186
C57BLKS/J m 12.05 0.5203 13.0759 11.0241
C58/J m 13.3833 0.4749 14.3198 12.4468
CBA/J m 10.3188 0.5817 11.4657 9.1718
DBA/2J m 11.9 0.6717 13.2244 10.5756
FVB/NJ m 12.6833 0.4749 13.6198 11.7468
I/LnJ m 9.4 0.5484 10.4814 8.3186
KK/HlJ m 13.76 0.5203 14.7859 12.7341
LP/J m 13.2875 0.5817 14.4345 12.1405
NOD/ShiLtJ m 11.52 0.5484 12.6014 10.4386
NZB/BlNJ m 14.625 0.5817 15.772 13.478
PL/J m 13.76 0.5203 14.7859 12.7341
SJL/J m 10.8667 0.5484 11.9481 9.7853
SM/J m 13.4136 0.4397 14.2806 12.5465
SWR/J m 12.36 0.5203 13.3859 11.3341




  GWAS USING LINEAR MIXED MODELS