Project measure / variable:   Maurer1   RR_ctrl

ID, description, units MPD:33237   RR_ctrl   interval RR   [ms]  control  
atenolol, isoproterenol study
Data set, strains Maurer1   inbred   23 strains     sex: m     age: 7-13wks
Procedure ECG
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  STRAIN COMPARISON PLOT
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Maurer1 - interval RR control



  MEASURE SUMMARY
Measure Summary Male
Number of strains tested23 strains
Mean of the strain means136   ms
Median of the strain means133   ms
SD of the strain means± 18.1
Coefficient of variation (CV)0.133
Min–max range of strain means106   –   176   ms
Mean sample size per strain9.8   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
strain 22 67404.9687 3063.8622 7.0987 < 0.0001
Residuals 202 87185.5692 431.6117


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ m 132.0 12.3   13 3.42 0.0933 109.0, 157.0 -0.21
A/J m 132.0 11.8   11 3.56 0.0896 115.0, 157.0 -0.21
AKR/J m 122.0 15.8   8 5.6 0.13 104.0, 150.0 -0.77
BALB/cByJ m 144.0 12.0   9 3.99 0.083 130.0, 164.0 0.45
BALB/cJ m 136.0 24.1   10 7.61 0.177 116.0, 193.0 0.01
BTBR T+ Itpr3tf/J m 144.0 22.8   10 7.2 0.158 113.0, 177.0 0.45
C3H/HeJ m 134.0 17.5   10 5.55 0.131 106.0, 155.0 -0.1
C3H/HeOuJ m 140.0 17.6   9 5.86 0.125 123.0, 178.0 0.23
C57BL/6J m 138.0 19.0   9 6.34 0.138 110.0, 164.0 0.12
C57BLKS/J m 168.0 24.6   10 7.77 0.146 131.0, 214.0 1.77
C58/J m 127.0 35.7   12 10.3 0.281 104.0, 237.0 -0.49
CBA/J m 126.0 17.3   8 6.12 0.137 105.0, 158.0 -0.54
DBA/2J m 163.0 8.85   6 3.61 0.0544 149.0, 172.0 1.5
FVB/NJ m 133.0 21.2   12 6.11 0.159 105.0, 179.0 -0.16
I/LnJ m 152.0 31.0   10 9.82 0.204 105.0, 209.0 0.89
KK/HlJ m 106.0 5.45   10 1.72 0.0516 95.5, 114.0 -1.65
LP/J m 132.0 19.0   8 6.73 0.144 106.0, 162.0 -0.21
NOD/ShiLtJ m 156.0 20.8   9 6.93 0.133 130.0, 192.0 1.11
NZB/BlNJ m 107.0 10.4   8 3.69 0.0978 99.0, 132.0 -1.59
PL/J m 176.0 44.1   10 13.9 0.251 120.0, 272.0 2.21
SJL/J m 118.0 13.1   9 4.38 0.112 97.4, 145.0 -0.99
SM/J m 123.0 8.92   14 2.38 0.0723 110.0, 135.0 -0.71
SWR/J m 116.0 8.13   10 2.57 0.0701 105.0, 134.0 -1.1


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ m 132.0769 5.762 143.4383 120.7155
A/J m 131.9091 6.264 144.2603 119.5579
AKR/J m 122.0 7.3452 136.483 107.517
BALB/cByJ m 144.2222 6.9251 157.877 130.5675
BALB/cJ m 136.2 6.5697 149.154 123.246
BTBR T+ Itpr3tf/J m 144.2 6.5697 157.154 131.246
C3H/HeJ m 133.6 6.5697 146.554 120.646
C3H/HeOuJ m 140.2222 6.9251 153.877 126.5675
C57BL/6J m 138.2222 6.9251 151.877 124.5675
C57BLKS/J m 168.1 6.5697 181.054 155.146
C58/J m 127.0 5.9973 138.8253 115.1747
CBA/J m 126.25 7.3452 140.733 111.767
DBA/2J m 162.6667 8.4815 179.3902 145.9431
FVB/NJ m 132.9167 5.9973 144.742 121.0913
I/LnJ m 152.3 6.5697 165.254 139.346
KK/HlJ m 105.75 6.5697 118.704 92.796
LP/J m 132.125 7.3452 146.608 117.642
NOD/ShiLtJ m 156.4444 6.9251 170.0992 142.7897
NZB/BlNJ m 106.625 7.3452 121.108 92.142
PL/J m 175.6 6.5697 188.554 162.646
SJL/J m 117.7111 6.9251 131.3658 104.0564
SM/J m 123.3571 5.5524 134.3053 112.409
SWR/J m 115.9 6.5697 128.854 102.946




  GWAS USING LINEAR MIXED MODELS