Project measure / variable:   Palmer2   methactivity_d3_OFT

ID, description, units MPD:30003   methactivity_d3_OFT   distance traveled   [cm]  day 3 Rx  
methamphetamine study
Data set, strains Palmer2   B6.A consomic w/par   21 strains     sex: both     age: 7-16wks
Procedure open field test
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  STRAIN COMPARISON PLOT
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Palmer2 - distance traveled day 3 Rx



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested21 strains21 strains
Mean of the strain means16142   cm 16392   cm
Median of the strain means16756   cm 17302   cm
SD of the strain means± 4639 ± 4112
Coefficient of variation (CV)0.287 0.251
Min–max range of strain means2622   –   22225   cm 4571   –   22821   cm
Mean sample size per strain10.4   mice 11.8   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 22290383.7745 22290383.7745 0.7141 0.3985
strain 20 7358914854.2315 367945742.7116 11.7882 < 0.0001
sex:strain 20 957805059.4483 47890252.9724 1.5343 0.065
Residuals 497 15512923518.5457 31213125.7918


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
A/J f 2622.0 2483.0   9 828.0 0.947 138.0, 7128.0 -2.91
A/J m 4571.0 4509.0   10 1426.0 0.986 93.0, 13697.0 -2.87
B6.A-Chr1 f 19151.0 10176.0   4 5088.0 0.531 7361.0, 32204.0 0.65
B6.A-Chr1 m 10442.0 3568.0   6 1457.0 0.342 6853.0, 14931.0 -1.45
B6.A-Chr10 f 20786.0 8253.0   13 2289.0 0.397 4841.0, 33263.0 1.0
B6.A-Chr10 m 20683.0 2620.0   16 655.0 0.127 14905.0, 24605.0 1.04
B6.A-Chr11 f 12136.0 4665.0   14 1247.0 0.384 5659.0, 20125.0 -0.86
B6.A-Chr11 m 12039.0 4570.0   23 953.0 0.38 5402.0, 20909.0 -1.06
B6.A-Chr12 f 22225.0 4319.0   15 1115.0 0.194 17091.0, 31203.0 1.31
B6.A-Chr12 m 19125.0 5165.0   34 886.0 0.27 9209.0, 31342.0 0.66
B6.A-Chr14 f 18382.0 6097.0   9 2032.0 0.332 8935.0, 28407.0 0.48
B6.A-Chr14 m 17302.0 5490.0   5 2455.0 0.317 12122.0, 23297.0 0.22
B6.A-Chr15 f 18316.0 6765.0   10 2139.0 0.369 11815.0, 33852.0 0.47
B6.A-Chr15 m 19366.0 3598.0   13 998.0 0.186 15649.0, 27151.0 0.72
B6.A-Chr16 f 10406.0 5328.0   13 1478.0 0.512 3017.0, 21626.0 -1.24
B6.A-Chr16 m 12074.0 4970.0   9 1657.0 0.412 5050.0, 20179.0 -1.05
B6.A-Chr17 f 17426.0 4562.0   3 2634.0 0.262 12887.0, 22010.0 0.28
B6.A-Chr17 m 22821.0 3828.0   9 1276.0 0.168 16100.0, 28937.0 1.56
B6.A-Chr18 f 15408.0 2514.0   5 1124.0 0.163 11072.0, 17236.0 -0.16
B6.A-Chr18 m 18581.0 5539.0   9 1846.0 0.298 7183.0, 25032.0 0.53
B6.A-Chr19 f 14905.0 7179.0   10 2270.0 0.482 6533.0, 27757.0 -0.27
B6.A-Chr19 m 19155.0 3898.0   10 1233.0 0.204 10532.0, 23843.0 0.67
B6.A-Chr2 f 16619.0 3782.0   10 1196.0 0.228 10702.0, 24145.0 0.1
B6.A-Chr2 m 18170.0 4234.0   10 1339.0 0.233 12648.0, 27551.0 0.43
B6.A-Chr3 f 21082.0 5592.0   8 1977.0 0.265 10225.0, 27327.0 1.06
B6.A-Chr3 m 18329.0 7759.0   14 2074.0 0.423 602.0, 31543.0 0.47
B6.A-Chr4 f 14051.0 4038.0   10 1277.0 0.287 9140.0, 20263.0 -0.45
B6.A-Chr4 m 16012.0 4749.0   9 1583.0 0.297 11436.0, 25479.0 -0.09
B6.A-Chr5 f 19108.0 5544.0   14 1482.0 0.29 8793.0, 26697.0 0.64
B6.A-Chr5 m 13584.0 6270.0   10 1983.0 0.462 1926.0, 26042.0 -0.68
B6.A-Chr6 f 16465.0 7193.0   10 2275.0 0.437 8218.0, 32092.0 0.07
B6.A-Chr6 m 15515.0 5441.0   9 1814.0 0.351 5041.0, 23622.0 -0.21
B6.A-Chr7 f 16756.0 5281.0   10 1670.0 0.315 10543.0, 23472.0 0.13
B6.A-Chr7 m 17237.0 4665.0   11 1407.0 0.271 10410.0, 25562.0 0.21
B6.A-Chr8 f 9146.0 4109.0   12 1186.0 0.449 3870.0, 16058.0 -1.51
B6.A-Chr8 m 14080.0 6314.0   8 2233.0 0.448 4134.0, 24215.0 -0.56
B6.A-Chr9 f 21411.0 7191.0   10 2274.0 0.336 9269.0, 33378.0 1.14
B6.A-Chr9 m 19298.0 4466.0   9 1489.0 0.231 11982.0, 26070.0 0.71
B6.A-ChrX f 15137.0 5969.0   12 1723.0 0.394 5194.0, 26756.0 -0.22
B6.A-ChrX m 18729.0 6805.0   6 2778.0 0.363 6201.0, 24178.0 0.57
C57BL/6J f 17435.0 6965.0   55 939.0 0.399 4643.0, 40199.0 0.28
C57BL/6J m 17119.0 5672.0   53 779.0 0.331 4845.0, 34423.0 0.18


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
A/J f 2621.6667 1862.2903 6280.5989 0.0
A/J m 4571.3 1766.7237 8042.4679 1100.1321
B6.A-Chr1 f 19150.75 2793.4354 24639.1484 13662.3516
B6.A-Chr1 m 10441.8333 2280.8305 14923.0918 5960.5748
B6.A-Chr10 f 20785.6154 1549.5192 23830.031 17741.1997
B6.A-Chr10 m 20683.4375 1396.7177 23427.6367 17939.2383
B6.A-Chr11 f 12136.2143 1493.154 15069.8866 9202.542
B6.A-Chr11 m 12038.8261 1164.9431 14327.6464 9750.0057
B6.A-Chr12 f 22225.4 1442.5238 25059.5967 19391.2033
B6.A-Chr12 m 19124.7941 958.1404 21007.2992 17242.289
B6.A-Chr14 f 18382.1111 1862.2903 22041.0434 14723.1789
B6.A-Chr14 m 17301.6 2498.5246 22210.5727 12392.6273
B6.A-Chr15 f 18316.2 1766.7237 21787.3679 14845.0321
B6.A-Chr15 m 19365.5385 1549.5192 22409.9541 16321.1228
B6.A-Chr16 f 10406.4615 1549.5192 13450.8772 7362.0459
B6.A-Chr16 m 12074.4444 1862.2903 15733.3767 8415.5122
B6.A-Chr17 f 17426.3333 3225.5814 23763.7899 11088.8768
B6.A-Chr17 m 22821.1111 1862.2903 26480.0434 19162.1789
B6.A-Chr18 f 15408.4 2498.5246 20317.3727 10499.4273
B6.A-Chr18 m 18581.0 1862.2903 22239.9322 14922.0678
B6.A-Chr19 f 14904.8 1766.7237 18375.9679 11433.6321
B6.A-Chr19 m 19154.9 1766.7237 22626.0679 15683.7321
B6.A-Chr2 f 16618.8 1766.7237 20089.9679 13147.6321
B6.A-Chr2 m 18170.3 1766.7237 21641.4679 14699.1321
B6.A-Chr3 f 21081.875 1975.2571 24962.7587 17200.9913
B6.A-Chr3 m 18329.2143 1493.154 21262.8866 15395.542
B6.A-Chr4 f 14051.1 1766.7237 17522.2679 10579.9321
B6.A-Chr4 m 16012.4444 1862.2903 19671.3767 12353.5122
B6.A-Chr5 f 19108.2143 1493.154 22041.8866 16174.542
B6.A-Chr5 m 13583.7 1766.7237 17054.8679 10112.5321
B6.A-Chr6 f 16464.6 1766.7237 19935.7679 12993.4321
B6.A-Chr6 m 15515.3333 1862.2903 19174.2656 11856.4011
B6.A-Chr7 f 16755.7 1766.7237 20226.8679 13284.5321
B6.A-Chr7 m 17237.1818 1684.5049 20546.8106 13927.5531
B6.A-Chr8 f 9145.6667 1612.7907 12314.3949 5976.9384
B6.A-Chr8 m 14079.75 1975.2571 17960.6337 10198.8663
B6.A-Chr9 f 21411.2 1766.7237 24882.3679 17940.0321
B6.A-Chr9 m 19298.0 1862.2903 22956.9322 15639.0678
B6.A-ChrX f 15136.9167 1612.7907 18305.6449 11968.1884
B6.A-ChrX m 18729.3333 2280.8305 23210.5918 14248.0748
C57BL/6J f 17434.8364 753.3335 18914.9473 15954.7254
C57BL/6J m 17119.4717 767.4157 18627.2507 15611.6927


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
A/J both 3596.4833 1283.495 6118.2284 1074.7383
B6.A-Chr1 both 14796.2917 1803.1548 18339.0376 11253.5458
B6.A-Chr10 both 20734.5264 1043.052 22783.8614 18685.1914
B6.A-Chr11 both 12087.5202 946.9162 13947.9725 10227.0678
B6.A-Chr12 both 20675.0971 865.8678 22376.3096 18973.8845
B6.A-Chr14 both 17841.8556 1558.1038 20903.1379 14780.5732
B6.A-Chr15 both 18840.8692 1174.9811 21149.4117 16532.3268
B6.A-Chr16 both 11240.453 1211.3149 13620.3822 8860.5238
B6.A-Chr17 both 20123.7222 1862.2903 23782.6545 16464.79
B6.A-Chr18 both 16994.7 1558.1038 20055.9824 13933.4176
B6.A-Chr19 both 17029.85 1249.2623 19484.3364 14575.3636
B6.A-Chr2 both 17394.55 1249.2623 19849.0364 14940.0636
B6.A-Chr3 both 19705.5446 1238.0579 22138.0172 17273.072
B6.A-Chr4 both 15031.7722 1283.495 17553.5172 12510.0272
B6.A-Chr5 both 16345.9571 1156.5921 18618.37 14073.5443
B6.A-Chr6 both 15989.9667 1283.495 18511.7117 13468.2216
B6.A-Chr7 both 16996.4409 1220.5398 19394.4948 14598.3871
B6.A-Chr8 both 11612.7083 1275.023 14117.808 9107.6087
B6.A-Chr9 both 20354.6 1283.495 22876.345 17832.855
B6.A-ChrX both 16933.125 1396.7177 19677.3242 14188.9258
C57BL/6J both 17277.154 537.6891 18333.5779 16220.7301




GWAS analysis not available: Strain panel must be either Inbred, HMDP, BXD, BXH, CXB, or AXB/BXA