Project measure / variable:   Palmer2   activity_d2_OFT

ID, description, units MPD:30002   activity_d2_OFT   distance traveled   [cm]  control (day 2)  
methamphetamine study
Data set, strains Palmer2   B6.A consomic w/par   21 strains     sex: both     age: 7-16wks
Procedure open field test
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  STRAIN COMPARISON PLOT
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Palmer2 - distance traveled control (day 2)



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested21 strains21 strains
Mean of the strain means3980   cm 4029   cm
Median of the strain means3824   cm 4176   cm
SD of the strain means± 1209 ± 1219
Coefficient of variation (CV)0.304 0.303
Min–max range of strain means1195   –   6405   cm 1367   –   6392   cm
Mean sample size per strain10.4   mice 11.8   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 1801277.9019 1801277.9019 1.0152 0.3142
strain 20 606630629.3104 30331531.4655 17.0947 < 0.0001
sex:strain 20 23763262.5859 1188163.1293 0.6696 0.8571
Residuals 497 881839528.2203 1774325.0065


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
A/J f 1195.0 691.0   9 230.0 0.578 154.0, 2097.0 -2.3
A/J m 1367.0 843.0   10 267.0 0.617 133.0, 3339.0 -2.18
B6.A-Chr1 f 3072.0 1194.0   4 597.0 0.389 1770.0, 4643.0 -0.75
B6.A-Chr1 m 3016.0 439.0   6 179.0 0.146 2540.0, 3747.0 -0.83
B6.A-Chr10 f 2446.0 1164.0   13 323.0 0.476 671.0, 4542.0 -1.27
B6.A-Chr10 m 2446.0 1096.0   16 274.0 0.448 1142.0, 5893.0 -1.3
B6.A-Chr11 f 3824.0 1089.0   14 291.0 0.285 2182.0, 5925.0 -0.13
B6.A-Chr11 m 4176.0 1223.0   23 255.0 0.293 2054.0, 7090.0 0.12
B6.A-Chr12 f 2929.0 1067.0   15 275.0 0.364 443.0, 4467.0 -0.87
B6.A-Chr12 m 2822.0 988.0   34 169.0 0.35 1125.0, 5074.0 -0.99
B6.A-Chr14 f 5772.0 1018.0   9 339.0 0.176 4603.0, 7198.0 1.48
B6.A-Chr14 m 5167.0 473.0   5 212.0 0.0916 4863.0, 5985.0 0.93
B6.A-Chr15 f 3695.0 952.0   10 301.0 0.258 2083.0, 5281.0 -0.24
B6.A-Chr15 m 3363.0 1809.0   13 502.0 0.538 1969.0, 8405.0 -0.55
B6.A-Chr16 f 2680.0 1148.0   13 318.0 0.428 810.0, 4742.0 -1.07
B6.A-Chr16 m 3073.0 626.0   9 209.0 0.204 2164.0, 3856.0 -0.78
B6.A-Chr17 f 4218.0 1121.0   3 647.0 0.266 3345.0, 5482.0 0.2
B6.A-Chr17 m 4962.0 1681.0   9 560.0 0.339 2837.0, 7714.0 0.77
B6.A-Chr18 f 3779.0 793.0   5 355.0 0.21 3031.0, 5025.0 -0.17
B6.A-Chr18 m 4004.0 1540.0   9 513.0 0.385 1913.0, 7085.0 -0.02
B6.A-Chr19 f 3761.0 1739.0   10 550.0 0.462 1923.0, 7682.0 -0.18
B6.A-Chr19 m 3338.0 1000.0   10 316.0 0.3 2361.0, 5700.0 -0.57
B6.A-Chr2 f 5178.0 1229.0   10 389.0 0.237 3602.0, 6947.0 0.99
B6.A-Chr2 m 4871.0 1710.0   10 541.0 0.351 1280.0, 7472.0 0.69
B6.A-Chr3 f 3509.0 1785.0   8 631.0 0.509 1645.0, 6830.0 -0.39
B6.A-Chr3 m 2955.0 1090.0   14 291.0 0.369 1305.0, 4317.0 -0.88
B6.A-Chr4 f 4808.0 1629.0   10 515.0 0.339 2536.0, 6962.0 0.69
B6.A-Chr4 m 4424.0 1066.0   9 355.0 0.241 2836.0, 6329.0 0.32
B6.A-Chr5 f 4767.0 1101.0   14 294.0 0.231 3347.0, 7482.0 0.65
B6.A-Chr5 m 4184.0 1694.0   10 536.0 0.405 1662.0, 7497.0 0.13
B6.A-Chr6 f 4436.0 1348.0   10 426.0 0.304 2026.0, 6398.0 0.38
B6.A-Chr6 m 4469.0 1062.0   9 354.0 0.238 2979.0, 5746.0 0.36
B6.A-Chr7 f 5584.0 1567.0   10 495.0 0.281 3337.0, 8470.0 1.33
B6.A-Chr7 m 6392.0 2002.0   11 604.0 0.313 3285.0, 10031.0 1.94
B6.A-Chr8 f 3352.0 1437.0   12 415.0 0.429 992.0, 5581.0 -0.52
B6.A-Chr8 m 4681.0 1790.0   8 633.0 0.382 2663.0, 7599.0 0.54
B6.A-Chr9 f 6405.0 1888.0   10 597.0 0.295 3316.0, 8669.0 2.01
B6.A-Chr9 m 6300.0 1517.0   9 506.0 0.241 3602.0, 8861.0 1.86
B6.A-ChrX f 4016.0 1467.0   12 423.0 0.365 2319.0, 7847.0 0.03
B6.A-ChrX m 4478.0 1755.0   6 717.0 0.392 1844.0, 7158.0 0.37
C57BL/6J f 4149.0 1415.0   55 191.0 0.341 1180.0, 7147.0 0.14
C57BL/6J m 4116.0 1349.0   53 185.0 0.328 1509.0, 7398.0 0.07


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
A/J f 1195.2222 444.0126 2067.5954 322.849
A/J m 1366.9 421.2274 2194.5059 539.2941
B6.A-Chr1 f 3072.25 666.019 4380.8098 1763.6902
B6.A-Chr1 m 3015.6667 543.8022 4084.1013 1947.232
B6.A-Chr10 f 2446.0 369.4408 3171.8584 1720.1416
B6.A-Chr10 m 2446.25 333.0095 3100.5299 1791.9701
B6.A-Chr11 f 3824.3571 356.0021 4523.8118 3124.9025
B6.A-Chr11 m 4176.3913 277.7491 4722.0985 3630.6841
B6.A-Chr12 f 2928.6 343.9307 3604.3374 2252.8626
B6.A-Chr12 m 2821.7941 228.4426 3270.6264 2372.9618
B6.A-Chr14 f 5771.6667 444.0126 6644.0399 4899.2935
B6.A-Chr14 m 5167.0 595.7055 6337.4115 3996.5885
B6.A-Chr15 f 3695.1 421.2274 4522.7059 2867.4941
B6.A-Chr15 m 3363.2308 369.4408 4089.0892 2637.3724
B6.A-Chr16 f 2679.5385 369.4408 3405.3969 1953.6801
B6.A-Chr16 m 3073.2222 444.0126 3945.5954 2200.849
B6.A-Chr17 f 4218.3333 769.0524 5729.3281 2707.3386
B6.A-Chr17 m 4962.4444 444.0126 5834.8177 4090.0712
B6.A-Chr18 f 3778.6 595.7055 4949.0115 2608.1885
B6.A-Chr18 m 4004.2222 444.0126 4876.5954 3131.849
B6.A-Chr19 f 3760.9 421.2274 4588.5059 2933.2941
B6.A-Chr19 m 3338.2 421.2274 4165.8059 2510.5941
B6.A-Chr2 f 5178.4 421.2274 6006.0059 4350.7941
B6.A-Chr2 m 4870.8 421.2274 5698.4059 4043.1941
B6.A-Chr3 f 3508.75 470.9465 4434.0415 2583.4585
B6.A-Chr3 m 2955.3571 356.0021 3654.8118 2255.9025
B6.A-Chr4 f 4808.5 421.2274 5636.1059 3980.8941
B6.A-Chr4 m 4424.0 444.0126 5296.3732 3551.6268
B6.A-Chr5 f 4766.7857 356.0021 5466.2404 4067.3311
B6.A-Chr5 m 4183.7 421.2274 5011.3059 3356.0941
B6.A-Chr6 f 4436.0 421.2274 5263.6059 3608.3941
B6.A-Chr6 m 4469.0 444.0126 5341.3732 3596.6268
B6.A-Chr7 f 5583.6 421.2274 6411.2059 4755.9941
B6.A-Chr7 m 6392.0909 401.6245 7181.1822 5602.9996
B6.A-Chr8 f 3352.1667 384.5262 4107.664 2596.6693
B6.A-Chr8 m 4680.875 470.9465 5606.1665 3755.5835
B6.A-Chr9 f 6405.3 421.2274 7232.9059 5577.6941
B6.A-Chr9 m 6299.8889 444.0126 7172.2621 5427.5157
B6.A-ChrX f 4015.5 384.5262 4770.9974 3260.0026
B6.A-ChrX m 4477.8333 543.8022 5546.268 3409.3987
C57BL/6J f 4148.8 179.612 4501.6923 3795.9077
C57BL/6J m 4115.6792 182.9695 4475.1683 3756.1902


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
A/J both 1281.0611 306.0146 1882.3029 679.8194
B6.A-Chr1 both 3043.9583 429.9134 3888.6301 2199.2866
B6.A-Chr10 both 2446.125 248.6875 2934.7334 1957.5166
B6.A-Chr11 both 4000.3742 225.7665 4443.9487 3556.7998
B6.A-Chr12 both 2875.1971 206.4427 3280.8051 2469.589
B6.A-Chr14 both 5469.3333 371.4876 6199.2131 4739.4535
B6.A-Chr15 both 3529.1654 280.1424 4079.5748 2978.756
B6.A-Chr16 both 2876.3803 288.8052 3443.8099 2308.9507
B6.A-Chr17 both 4590.3889 444.0126 5462.7621 3718.0157
B6.A-Chr18 both 3891.4111 371.4876 4621.2909 3161.5313
B6.A-Chr19 both 3549.55 297.8527 4134.7557 2964.3443
B6.A-Chr2 both 5024.6 297.8527 5609.8057 4439.3943
B6.A-Chr3 both 3232.0536 295.1814 3812.0107 2652.0964
B6.A-Chr4 both 4616.25 306.0146 5217.4917 4015.0083
B6.A-Chr5 both 4475.2429 275.758 5017.0381 3933.4476
B6.A-Chr6 both 4452.5 306.0146 5053.7417 3851.2583
B6.A-Chr7 both 5987.8455 291.0046 6559.5964 5416.0945
B6.A-Chr8 both 4016.5208 303.9947 4613.7939 3419.2477
B6.A-Chr9 both 6352.5944 306.0146 6953.8362 5751.3527
B6.A-ChrX both 4246.6667 333.0095 4900.9466 3592.3868
C57BL/6J both 4132.2396 128.1974 4384.1153 3880.364




GWAS analysis not available: Strain panel must be either Inbred, HMDP, BXD, BXH, CXB, or AXB/BXA