Project measure / variable:   Eumorphia7   IgG3

ID, description, units MPD:29602   IgG3   immunoglobulin G3 (serum IgG3)   [µg/mL]  
Data set, strains Eumorphia7   inbred   6 strains     sex: both     age: 9-12wks
Procedure immunoglobulin quantification
Ontology mappings

  STRAIN COMPARISON PLOT
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Eumorphia7 - immunoglobulin G3 (serum IgG3)



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested6 strains5 strains
Mean of the strain means27.4   µg/mL 25.6   µg/mL
Median of the strain means23.2   µg/mL 23.3   µg/mL
SD of the strain means± 12.3 ± 11.5
Coefficient of variation (CV)0.448 0.450
Min–max range of strain means15.9   –   46.8   µg/mL 15.1   –   45.2   µg/mL
Mean sample size per strain5.0   mice 5.0   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 220.0802 220.0802 1.8908 0.1768
strain 4 5065.35 1266.3375 10.8798 < 0.0001
sex:strain 4 560.9308 140.2327 1.2048 0.3238
Residuals 40 4655.724 116.3931


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129P2/OlaHsd f 15.9 2.13   5 0.954 0.134 14.0, 19.5 -0.94
BALB/cByJ f 38.0 6.12   5 2.74 0.161 32.0, 45.0 0.86
BALB/cByJ m 23.6 8.82   5 3.94 0.374 18.0, 39.0 -0.17
BALB/cJ f 46.8 26.8   5 12.0 0.573 26.0, 90.0 1.57
BALB/cJ m 45.2 10.5   5 4.68 0.232 30.0, 58.0 1.71
C3H/HeNCrl f 17.4 3.42   5 1.53 0.196 14.0, 21.0 -0.82
C3H/HeNCrl m 23.3 7.33   5 3.28 0.315 15.5, 32.0 -0.2
C57BL/6J f 23.9 7.98   5 3.57 0.333 17.2, 36.0 -0.29
C57BL/6J m 20.6 8.2   5 3.67 0.399 10.3, 29.0 -0.43
CBA/J f 22.6 4.23   5 1.89 0.187 17.5, 27.0 -0.39
CBA/J m 15.1 2.47   5 1.11 0.164 12.0, 18.0 -0.91


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
BALB/cByJ f 38.0 4.8248 47.7513 28.2487
BALB/cByJ m 23.6 4.8248 33.3513 13.8487
BALB/cJ f 46.8 4.8248 56.5513 37.0487
BALB/cJ m 45.2 4.8248 54.9513 35.4487
C3H/HeNCrl f 17.4 4.8248 27.1513 7.6487
C3H/HeNCrl m 23.3 4.8248 33.0513 13.5487
C57BL/6J f 23.94 4.8248 33.6913 14.1887
C57BL/6J m 20.56 4.8248 30.3113 10.8087
CBA/J f 22.6 4.8248 32.3513 12.8487
CBA/J m 15.1 4.8248 24.8513 5.3487


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
BALB/cByJ both 30.8 3.4116 37.6952 23.9048
BALB/cJ both 46.0 3.4116 52.8952 39.1048
C3H/HeNCrl both 20.35 3.4116 27.2452 13.4548
C57BL/6J both 22.25 3.4116 29.1452 15.3548
CBA/J both 18.85 3.4116 25.7452 11.9548




  GWAS USING LINEAR MIXED MODELS