Project measure / variable:   Paigen3   bw_chg

ID, description, units MPD:2833   bw_chg   body weight   [g]  fold change  
high-fat diet study
Data set, strains Paigen3   obesity mutants   8 strains     sex: both     age: 7-11wks
Procedure body weight
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  STRAIN COMPARISON PLOT
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Paigen3 - body weight fold change



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested7 strains8 strains
Mean of the strain means1.06   g 1.07   g
Median of the strain means1.07   g 1.04   g
SD of the strain means± 0.0709 ± 0.127
Coefficient of variation (CV)0.0671 0.119
Min–max range of strain means0.945   –   1.13   g 0.925   –   1.28   g
Mean sample size per strain20.6   mice 20.0   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 0.0503 0.0503 2.2791 0.1323
strain 6 0.9509 0.1585 7.1778 < 0.0001
sex:strain 6 1.2706 0.2118 9.5908 < 0.0001
Residuals 274 6.0501 0.0221


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
B6(AU)-Tubtub/J f 1.07 0.211   24 0.043 0.196 0.624, 1.44 0.2
B6(AU)-Tubtub/J m 1.05 0.166   24 0.0338 0.157 0.712, 1.4 -0.14
B6.BKS(D)-Leprdb/J m 1.22 0.16   16 0.04 0.131 0.855, 1.49 1.2
B6.Cg-Ay/J f 0.978 0.137   23 0.0286 0.14 0.678, 1.21 -1.1
B6.Cg-Ay/J m 0.925 0.124   34 0.0212 0.134 0.716, 1.23 -1.12
B6.Cg-Lepob/J f 1.13 0.0556   17 0.0135 0.0492 0.984, 1.2 1.04
B6.Cg-Lepob/J m 1.1 0.091   21 0.0199 0.0824 0.863, 1.29 0.26
BKS.Cg-Dock7m +/+ Leprdb/J f 0.945 0.195   18 0.046 0.207 0.635, 1.35 -1.57
BKS.Cg-Dock7m +/+ Leprdb/J m 1.28 0.241   15 0.0621 0.188 0.809, 1.67 1.67
BKSChpLt.HRS-Cpefat/J f 1.05 0.251   16 0.0627 0.238 0.735, 1.61 -0.09
BKSChpLt.HRS-Cpefat/J m 0.948 0.141   18 0.0332 0.148 0.645, 1.23 -0.94
C57BL/6J f 1.12 0.0976   19 0.0224 0.0874 0.889, 1.29 0.9
C57BL/6J m 0.976 0.0779   15 0.0201 0.0798 0.855, 1.13 -0.72
C57BLKS/J f 1.1 0.0868   27 0.0167 0.0788 0.94, 1.26 0.62
C57BLKS/J m 1.04 0.0662   17 0.0161 0.0639 0.93, 1.2 -0.21


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
B6(AU)-Tubtub/J f 1.0727 0.0303 1.1325 1.013
B6(AU)-Tubtub/J m 1.0528 0.0303 1.1125 0.9931
B6.Cg-Ay/J f 0.978 0.031 1.039 0.917
B6.Cg-Ay/J m 0.925 0.0255 0.9752 0.8748
B6.Cg-Lepob/J f 1.1312 0.036 1.2021 1.0602
B6.Cg-Lepob/J m 1.1048 0.0324 1.1686 1.041
BKS.Cg-Dock7m +/+ Leprdb/J f 0.9445 0.035 1.0135 0.8755
BKS.Cg-Dock7m +/+ Leprdb/J m 1.2829 0.0384 1.3585 1.2074
BKSChpLt.HRS-Cpefat/J f 1.0538 0.0371 1.1269 0.9807
BKSChpLt.HRS-Cpefat/J m 0.9483 0.035 1.0173 0.8794
C57BL/6J f 1.1165 0.0341 1.1836 1.0494
C57BL/6J m 0.9763 0.0384 1.0519 0.9008
C57BLKS/J f 1.1021 0.0286 1.1584 1.0458
C57BLKS/J m 1.0364 0.036 1.1073 0.9654


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
B6(AU)-Tubtub/J both 1.0628 0.0214 1.105 1.0205
B6.Cg-Ay/J both 0.9515 0.0201 0.991 0.912
B6.Cg-Lepob/J both 1.118 0.0242 1.1657 1.0703
BKS.Cg-Dock7m +/+ Leprdb/J both 1.1137 0.026 1.1649 1.0626
BKSChpLt.HRS-Cpefat/J both 1.0011 0.0255 1.0513 0.9508
C57BL/6J both 1.0464 0.0257 1.0969 0.9959
C57BLKS/J both 1.0692 0.023 1.1145 1.0239




GWAS analysis not available: Strain panel must be either Inbred, HMDP, BXD, BXH, CXB, or AXB/BXA