Project measure / variable:   Svenson4   BMC

ID, description, units MPD:27402   BMC   bone mineral content (BMC)   [g]  
Data set, strains Svenson4   B6.PWD consomic w/par   28 strains     sex: both     age: 16wks
Procedure DXA
Ontology mappings

  STRAIN COMPARISON PLOT
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Svenson4 - bone mineral content (BMC)



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested28 strains28 strains
Mean of the strain means0.533   g 0.551   g
Median of the strain means0.536   g 0.554   g
SD of the strain means± 0.0491 ± 0.0433
Coefficient of variation (CV)0.0921 0.0786
Min–max range of strain means0.441   –   0.653   g 0.474   –   0.635   g
Mean sample size per strain9.9   mice 9.3   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 0.058 0.058 24.0116 < 0.0001
strain 27 0.7891 0.0292 12.0989 < 0.0001
sex:strain 27 0.3133 0.0116 4.8035 < 0.0001
Residuals 498 1.203 0.0024


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
B6.PWD-Chr1 f 0.536 0.0434   8 0.0153 0.081 0.452, 0.581 0.06
B6.PWD-Chr1 m 0.521 0.0259   8 0.00915 0.0497 0.482, 0.565 -0.69
B6.PWD-Chr10.1 f 0.473 0.0573   12 0.0166 0.121 0.36, 0.566 -1.22
B6.PWD-Chr10.1 m 0.592 0.0801   10 0.0253 0.135 0.517, 0.732 0.95
B6.PWD-Chr10.2 f 0.568 0.0549   14 0.0147 0.0966 0.487, 0.688 0.71
B6.PWD-Chr10.2 m 0.572 0.0495   13 0.0137 0.0865 0.493, 0.657 0.48
B6.PWD-Chr10.3 f 0.508 0.0399   9 0.0133 0.0786 0.449, 0.549 -0.51
B6.PWD-Chr10.3 m 0.549 0.0416   8 0.0147 0.0757 0.471, 0.612 -0.05
B6.PWD-Chr11.1 f 0.566 0.0495   9 0.0165 0.0875 0.49, 0.663 0.67
B6.PWD-Chr11.1 m 0.602 0.0387   8 0.0137 0.0643 0.548, 0.67 1.18
B6.PWD-Chr11.2 f 0.495 0.0425   11 0.0128 0.0858 0.434, 0.568 -0.77
B6.PWD-Chr11.2 m 0.566 0.0647   12 0.0187 0.114 0.468, 0.66 0.35
B6.PWD-Chr11.3 f 0.486 0.038   11 0.0115 0.0783 0.411, 0.547 -0.96
B6.PWD-Chr11.3 m 0.474 0.0334   8 0.0118 0.0705 0.426, 0.522 -1.78
B6.PWD-Chr12 f 0.535 0.0379   8 0.0134 0.0708 0.476, 0.585 0.04
B6.PWD-Chr12 m 0.508 0.0325   8 0.0115 0.0639 0.479, 0.577 -0.99
B6.PWD-Chr13 f 0.441 0.0437   8 0.0154 0.0991 0.38, 0.501 -1.87
B6.PWD-Chr13 m 0.484 0.0496   8 0.0175 0.103 0.421, 0.57 -1.55
B6.PWD-Chr14 f 0.568 0.0437   8 0.0155 0.0769 0.508, 0.638 0.71
B6.PWD-Chr14 m 0.526 0.0497   8 0.0176 0.0945 0.444, 0.59 -0.58
B6.PWD-Chr15 f 0.577 0.0356   8 0.0126 0.0617 0.517, 0.635 0.9
B6.PWD-Chr15 m 0.635 0.0506   8 0.0179 0.0797 0.578, 0.696 1.94
B6.PWD-Chr16 f 0.484 0.0496   8 0.0175 0.102 0.414, 0.553 -1.0
B6.PWD-Chr16 m 0.496 0.0245   8 0.00866 0.0494 0.471, 0.542 -1.27
B6.PWD-Chr17 f 0.553 0.0517   9 0.0172 0.0934 0.5, 0.646 0.41
B6.PWD-Chr17 m 0.602 0.053   10 0.0168 0.088 0.538, 0.681 1.18
B6.PWD-Chr18 f 0.602 0.0398   9 0.0133 0.0662 0.55, 0.655 1.41
B6.PWD-Chr18 m 0.555 0.0343   9 0.0114 0.0618 0.502, 0.604 0.09
B6.PWD-Chr19 f 0.566 0.0225   8 0.00794 0.0397 0.524, 0.593 0.67
B6.PWD-Chr19 m 0.488 0.0336   8 0.0119 0.0688 0.447, 0.555 -1.45
B6.PWD-Chr2 f 0.595 0.0676   9 0.0225 0.114 0.473, 0.728 1.26
B6.PWD-Chr2 m 0.631 0.0791   10 0.025 0.125 0.537, 0.763 1.85
B6.PWD-Chr3 f 0.562 0.046   8 0.0162 0.0818 0.508, 0.608 0.59
B6.PWD-Chr3 m 0.587 0.0411   8 0.0145 0.07 0.54, 0.668 0.83
B6.PWD-Chr5 f 0.653 0.0389   10 0.0123 0.0596 0.59, 0.706 2.45
B6.PWD-Chr5 m 0.555 0.0489   14 0.0131 0.0881 0.508, 0.663 0.09
B6.PWD-Chr6 f 0.506 0.033   10 0.0104 0.0653 0.471, 0.556 -0.55
B6.PWD-Chr6 m 0.532 0.0451   8 0.0159 0.0847 0.456, 0.594 -0.44
B6.PWD-Chr8 f 0.474 0.0388   4 0.0194 0.0819 0.416, 0.499 -1.2
B6.PWD-Chr8 m 0.565 0.0734   5 0.0328 0.13 0.474, 0.64 0.32
B6.PWD-Chr9 f 0.479 0.0372   8 0.0131 0.0776 0.422, 0.53 -1.1
B6.PWD-Chr9 m 0.553 0.064   8 0.0226 0.116 0.459, 0.631 0.05
B6.PWD-ChrX.1 f 0.595 0.0302   8 0.0107 0.0507 0.555, 0.637 1.26
B6.PWD-ChrX.1 m 0.591 0.0607   8 0.0215 0.103 0.524, 0.675 0.92
B6.PWD-ChrX.2 f 0.512 0.0331   13 0.00918 0.0647 0.441, 0.56 -0.43
B6.PWD-ChrX.2 m 0.514 0.0576   9 0.0192 0.112 0.443, 0.62 -0.85
B6.PWD-ChrX.3 f 0.492 0.0425   17 0.0103 0.0863 0.419, 0.556 -0.83
B6.PWD-ChrX.3 m 0.567 0.0551   8 0.0195 0.0971 0.463, 0.629 0.37
B6.PWD-ChrY f 0.547 0.0431   8 0.0152 0.0787 0.495, 0.623 0.29
B6.PWD-ChrY m 0.546 0.0521   8 0.0184 0.0955 0.488, 0.608 -0.12
B6.PWD-mt f 0.545 0.0443   8 0.0157 0.0812 0.506, 0.642 0.25
B6.PWD-mt m 0.571 0.0658   8 0.0233 0.115 0.471, 0.661 0.46
C57BL/6J f 0.51 0.0565   19 0.013 0.111 0.382, 0.587 -0.47
C57BL/6J m 0.553 0.0342   19 0.00784 0.0618 0.504, 0.618 0.05
PWD/PhJ f 0.494 0.0516   23 0.0108 0.104 0.406, 0.605 -0.79
PWD/PhJ m 0.493 0.0642   22 0.0137 0.13 0.38, 0.606 -1.34


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
B6.PWD-Chr1 f 0.5362 0.0174 0.5704 0.5021
B6.PWD-Chr1 m 0.5209 0.0174 0.5551 0.4868
B6.PWD-Chr10.1 f 0.4728 0.0142 0.5007 0.4449
B6.PWD-Chr10.1 m 0.5919 0.0155 0.6224 0.5613
B6.PWD-Chr10.2 f 0.5682 0.0131 0.594 0.5424
B6.PWD-Chr10.2 m 0.5717 0.0136 0.5985 0.545
B6.PWD-Chr10.3 f 0.5082 0.0164 0.5404 0.476
B6.PWD-Chr10.3 m 0.5493 0.0174 0.5834 0.5151
B6.PWD-Chr11.1 f 0.5661 0.0164 0.5983 0.5339
B6.PWD-Chr11.1 m 0.6023 0.0174 0.6364 0.5681
B6.PWD-Chr11.2 f 0.4946 0.0148 0.5237 0.4655
B6.PWD-Chr11.2 m 0.5656 0.0142 0.5935 0.5378
B6.PWD-Chr11.3 f 0.4861 0.0148 0.5152 0.457
B6.PWD-Chr11.3 m 0.4741 0.0174 0.5083 0.44
B6.PWD-Chr12 f 0.5347 0.0174 0.5688 0.5006
B6.PWD-Chr12 m 0.5085 0.0174 0.5426 0.4743
B6.PWD-Chr13 f 0.4406 0.0174 0.4748 0.4065
B6.PWD-Chr13 m 0.4835 0.0174 0.5177 0.4494
B6.PWD-Chr14 f 0.568 0.0174 0.6021 0.5339
B6.PWD-Chr14 m 0.526 0.0174 0.5601 0.4918
B6.PWD-Chr15 f 0.5768 0.0174 0.611 0.5427
B6.PWD-Chr15 m 0.6354 0.0174 0.6695 0.6013
B6.PWD-Chr16 f 0.4837 0.0174 0.5179 0.4496
B6.PWD-Chr16 m 0.4964 0.0174 0.5305 0.4622
B6.PWD-Chr17 f 0.5535 0.0164 0.5857 0.5213
B6.PWD-Chr17 m 0.6023 0.0155 0.6329 0.5718
B6.PWD-Chr18 f 0.6019 0.0164 0.634 0.5697
B6.PWD-Chr18 m 0.5554 0.0164 0.5876 0.5232
B6.PWD-Chr19 f 0.5657 0.0174 0.5999 0.5316
B6.PWD-Chr19 m 0.4882 0.0174 0.5223 0.454
B6.PWD-Chr2 f 0.5952 0.0164 0.6274 0.563
B6.PWD-Chr2 m 0.6313 0.0155 0.6618 0.6008
B6.PWD-Chr3 f 0.5617 0.0174 0.5958 0.5275
B6.PWD-Chr3 m 0.587 0.0174 0.6212 0.5529
B6.PWD-Chr5 f 0.653 0.0155 0.6836 0.6225
B6.PWD-Chr5 m 0.5555 0.0131 0.5813 0.5297
B6.PWD-Chr6 f 0.5056 0.0155 0.5362 0.4751
B6.PWD-Chr6 m 0.5322 0.0174 0.5664 0.4981
B6.PWD-Chr8 f 0.474 0.0246 0.5223 0.4258
B6.PWD-Chr8 m 0.5651 0.022 0.6083 0.522
B6.PWD-Chr9 f 0.4787 0.0174 0.5129 0.4446
B6.PWD-Chr9 m 0.5527 0.0174 0.5869 0.5186
B6.PWD-ChrX.1 f 0.5951 0.0174 0.6292 0.5609
B6.PWD-ChrX.1 m 0.591 0.0174 0.6252 0.5569
B6.PWD-ChrX.2 f 0.5121 0.0136 0.5389 0.4853
B6.PWD-ChrX.2 m 0.5138 0.0164 0.546 0.4816
B6.PWD-ChrX.3 f 0.4923 0.0119 0.5157 0.4689
B6.PWD-ChrX.3 m 0.567 0.0174 0.6011 0.5328
B6.PWD-ChrY f 0.5468 0.0174 0.5809 0.5126
B6.PWD-ChrY m 0.5455 0.0174 0.5797 0.5114
B6.PWD-mt f 0.5452 0.0174 0.5794 0.5111
B6.PWD-mt m 0.571 0.0174 0.6051 0.5368
C57BL/6J f 0.51 0.0113 0.5322 0.4879
C57BL/6J m 0.5528 0.0113 0.5749 0.5306
PWD/PhJ f 0.4938 0.0102 0.5139 0.4736
PWD/PhJ m 0.4931 0.0105 0.5137 0.4726


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
B6.PWD-Chr1 both 0.5286 0.0123 0.5527 0.5045
B6.PWD-Chr10.1 both 0.5323 0.0105 0.553 0.5117
B6.PWD-Chr10.2 both 0.57 0.0095 0.5886 0.5514
B6.PWD-Chr10.3 both 0.5287 0.0119 0.5522 0.5053
B6.PWD-Chr11.1 both 0.5842 0.0119 0.6077 0.5607
B6.PWD-Chr11.2 both 0.5301 0.0103 0.5503 0.51
B6.PWD-Chr11.3 both 0.4801 0.0114 0.5025 0.4577
B6.PWD-Chr12 both 0.5216 0.0123 0.5457 0.4974
B6.PWD-Chr13 both 0.4621 0.0123 0.4862 0.4379
B6.PWD-Chr14 both 0.547 0.0123 0.5711 0.5228
B6.PWD-Chr15 both 0.6061 0.0123 0.6302 0.582
B6.PWD-Chr16 both 0.49 0.0123 0.5142 0.4659
B6.PWD-Chr17 both 0.5779 0.0113 0.6001 0.5557
B6.PWD-Chr18 both 0.5786 0.0116 0.6014 0.5559
B6.PWD-Chr19 both 0.527 0.0123 0.5511 0.5028
B6.PWD-Chr2 both 0.6133 0.0113 0.6354 0.5911
B6.PWD-Chr3 both 0.5743 0.0123 0.5985 0.5502
B6.PWD-Chr5 both 0.6042 0.0102 0.6242 0.5843
B6.PWD-Chr6 both 0.5189 0.0117 0.5418 0.496
B6.PWD-Chr8 both 0.5196 0.0165 0.552 0.4872
B6.PWD-Chr9 both 0.5157 0.0123 0.5399 0.4916
B6.PWD-ChrX.1 both 0.5931 0.0123 0.6172 0.5689
B6.PWD-ChrX.2 both 0.5129 0.0107 0.5339 0.492
B6.PWD-ChrX.3 both 0.5296 0.0105 0.5503 0.5089
B6.PWD-ChrY both 0.5461 0.0123 0.5703 0.522
B6.PWD-mt both 0.5581 0.0123 0.5823 0.534
C57BL/6J both 0.5314 0.008 0.5471 0.5158
PWD/PhJ both 0.4934 0.0073 0.5078 0.4791




GWAS analysis not available: Strain panel must be either Inbred, HMDP, BXD, BXH, CXB, or AXB/BXA