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Project measure / variable:   Svenson3   HDL

ID, description, units MPD:27365   HDL   HDL cholesterol (plasma HDL)   [mg/dL]  
Data set, strains Svenson3   B6.PWD consomic w/par   28 strains     sex: both     age: 8wks
Procedure lipid profile
Ontology mappings

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  STRAIN COMPARISON PLOT
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Svenson3 - HDL cholesterol (plasma HDL)



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested27 strains28 strains
Mean of the strain means63.3   mg/dL 80.0   mg/dL
Median of the strain means64.4   mg/dL 81.3   mg/dL
SD of the strain means± 8.39 ± 10.4
Coefficient of variation (CV)0.133 0.131
Min–max range of strain means41.8   –   76.4   mg/dL 61.6   –   97.0   mg/dL
Mean sample size per strain7.1   mice 7.3   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 28280.7121 28280.7121 380.0972 < 0.0001
strain 26 25813.2085 992.8157 13.3436 < 0.0001
sex:strain 26 5237.473 201.4413 2.7074 < 0.0001
Residuals 337 25074.1144 74.4039


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
Select table page:
Strain Sex Mean SD N mice SEM CV Min, Max Z score
B6.PWD-Chr1 f 65.9 6.79   8 2.4 0.103 57.7, 78.2 0.32
B6.PWD-Chr1 m 93.6 12.2   10 3.85 0.13 71.6, 108.0 1.3
B6.PWD-Chr10.1 f 64.4 9.73   7 3.68 0.151 48.5, 78.5 0.14
B6.PWD-Chr10.1 m 68.3 7.44   7 2.81 0.109 57.8, 78.7 -1.12
B6.PWD-Chr10.2 f 53.8 11.0   7 4.17 0.205 40.5, 65.1 -1.13
B6.PWD-Chr10.2 m 64.6 7.45   3 4.3 0.115 57.2, 72.1 -1.48
B6.PWD-Chr10.3 f 53.2 6.09   8 2.15 0.114 45.1, 61.8 -1.2
B6.PWD-Chr10.3 m 61.6 4.9   8 1.73 0.0796 52.8, 67.5 -1.76
B6.PWD-Chr11.1 f 41.8 1.48   2   1.05 0.0356 40.7, 42.8 -2.56
B6.PWD-Chr11.1 m 63.0 3.68   2   2.6 0.0584 60.4, 65.6 -1.63
B6.PWD-Chr11.2 f 60.0 5.84   4 2.92 0.0973 52.0, 66.0 -0.39
B6.PWD-Chr11.2 m 71.8 6.15   2   4.35 0.0856 67.5, 76.2 -0.79
B6.PWD-Chr11.3 f 69.7 5.8   8 2.05 0.0833 60.3, 79.2 0.77
B6.PWD-Chr11.3 m 77.2 12.4   8 4.39 0.161 61.3, 99.0 -0.27
B6.PWD-Chr12 f 63.1 8.16   9 2.72 0.129 53.1, 80.5 -0.02
B6.PWD-Chr12 m 86.2 6.57   10 2.08 0.0762 76.8, 96.9 0.59
B6.PWD-Chr13 f 67.9 8.9   8 3.15 0.131 56.6, 81.2 0.55
B6.PWD-Chr13 m 81.9 8.49   8 3.0 0.104 71.8, 93.9 0.18
B6.PWD-Chr14 f 63.5 7.59   10 2.4 0.119 52.2, 72.3 0.03
B6.PWD-Chr14 m 80.4 7.07   10 2.23 0.0879 71.2, 92.6 0.04
B6.PWD-Chr15 f 73.0 7.08   8 2.5 0.0969 60.5, 84.3 1.16
B6.PWD-Chr15 m 86.5 7.12   8 2.52 0.0823 75.4, 96.9 0.62
B6.PWD-Chr16 f 69.3 5.96   8 2.11 0.086 62.5, 79.2 0.72
B6.PWD-Chr16 m 83.9 9.22   8 3.26 0.11 70.1, 94.7 0.37
B6.PWD-Chr17 f 74.5 1.94   4 0.969 0.026 72.3, 76.6 1.34
B6.PWD-Chr17 m 93.4 7.57   3 4.37 0.0811 85.1, 99.9 1.28
B6.PWD-Chr18 f 59.7 3.39   5 1.52 0.0568 55.6, 63.5 -0.42
B6.PWD-Chr18 m 65.5 8.62   9 2.87 0.132 50.2, 76.6 -1.39
B6.PWD-Chr19 f 76.4 11.7   8 4.13 0.153 67.7, 104.0 1.57
B6.PWD-Chr19 m 97.0 14.0   8 4.97 0.145 67.4, 113.0 1.63
B6.PWD-Chr2 f 53.0 12.5   7 4.73 0.236 32.2, 71.3 -1.22
B6.PWD-Chr2 m 87.6 10.5   10 3.33 0.12 67.3, 99.7 0.73
B6.PWD-Chr3 f 54.8 3.97   8 1.4 0.0724 49.9, 62.0 -1.01
B6.PWD-Chr3 m 68.6 4.39   9 1.46 0.0639 62.1, 73.0 -1.09
B6.PWD-Chr5 f 57.5 10.0   7 3.78 0.174 49.2, 73.6 -0.69
B6.PWD-Chr5 m 81.3 9.2   8 3.25 0.113 65.3, 91.2 0.12
B6.PWD-Chr6 f 64.6 7.33   7 2.77 0.114 54.1, 78.1 0.16
B6.PWD-Chr6 m 83.0 12.6   8 4.46 0.152 60.6, 99.4 0.29
B6.PWD-Chr8 m 76.5 3.31   3 1.91 0.0432 74.1, 80.3 -0.34
B6.PWD-Chr9 f 56.2 8.81   9 2.94 0.157 43.1, 65.6 -0.84
B6.PWD-Chr9 m 75.8 5.93   8 2.1 0.0783 63.0, 84.3 -0.4
B6.PWD-ChrX.1 f 74.8 7.45   8 2.63 0.0996 63.6, 87.1 1.38
B6.PWD-ChrX.1 m 96.7 10.5   8 3.72 0.109 85.0, 115.0 1.6
B6.PWD-ChrX.2 f 73.9 8.02   6 3.28 0.109 64.9, 86.3 1.27
B6.PWD-ChrX.2 m 78.5 11.7   9 3.9 0.149 61.9, 101.0 -0.14
B6.PWD-ChrX.3 f 63.0 2.29   3 1.32 0.0364 60.4, 64.8 -0.03
B6.PWD-ChrX.3 m 81.3 8.19   4 4.09 0.101 69.3, 87.3 0.12
B6.PWD-ChrY f 66.2 5.99   8 2.12 0.0905 56.8, 73.2 0.35
B6.PWD-ChrY m 89.9 6.24   7 2.36 0.0694 78.9, 95.3 0.95
B6.PWD-mt f 67.2 7.6   8 2.69 0.113 56.4, 76.5 0.47
B6.PWD-mt m 91.9 9.86   8 3.49 0.107 79.3, 108.0 1.14
C57BL/6J f 53.1 7.42   8 2.62 0.14 37.4, 60.9 -1.21
C57BL/6J m 68.8 10.9   12 3.15 0.159 42.5, 83.2 -1.07
PWD/PhJ f 67.4 7.41   7 2.8 0.11 56.0, 75.2 0.49
PWD/PhJ m 85.5 4.11   6 1.68 0.048 78.5, 89.9 0.53


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
B6.PWD-Chr1 f 65.925 3.0497 71.9238 59.9262
B6.PWD-Chr1 m 93.58 2.7277 98.9455 88.2145
B6.PWD-Chr10.1 f 64.3857 3.2602 70.7987 57.9727
B6.PWD-Chr10.1 m 68.3286 3.2602 74.7415 61.9156
B6.PWD-Chr10.2 f 53.8429 3.2602 60.2558 47.4299
B6.PWD-Chr10.2 m 64.6 4.9801 74.396 54.804
B6.PWD-Chr10.3 f 53.2375 3.0497 59.2363 47.2387
B6.PWD-Chr10.3 m 61.55 3.0497 67.5488 55.5512
B6.PWD-Chr11.1 f 41.75 6.0993 53.7476 29.7524
B6.PWD-Chr11.1 m 63.0 6.0993 74.9976 51.0024
B6.PWD-Chr11.2 f 59.975 4.3129 68.4586 51.4914
B6.PWD-Chr11.2 m 71.85 6.0993 83.8476 59.8524
B6.PWD-Chr11.3 f 69.6875 3.0497 75.6863 63.6887
B6.PWD-Chr11.3 m 77.225 3.0497 83.2238 71.2262
B6.PWD-Chr12 f 63.0556 2.8753 68.7113 57.3998
B6.PWD-Chr12 m 86.22 2.7277 91.5855 80.8545
B6.PWD-Chr13 f 67.9125 3.0497 73.9113 61.9137
B6.PWD-Chr13 m 81.8625 3.0497 87.8613 75.8637
B6.PWD-Chr14 f 63.53 2.7277 68.8955 58.1645
B6.PWD-Chr14 m 80.41 2.7277 85.7755 75.0445
B6.PWD-Chr15 f 73.025 3.0497 79.0238 67.0262
B6.PWD-Chr15 m 86.4875 3.0497 92.4863 80.4887
B6.PWD-Chr16 f 69.275 3.0497 75.2738 63.2762
B6.PWD-Chr16 m 83.8875 3.0497 89.8863 77.8887
B6.PWD-Chr17 f 74.525 4.3129 83.0086 66.0414
B6.PWD-Chr17 m 93.4333 4.9801 103.2293 83.6374
B6.PWD-Chr18 f 59.72 3.8576 67.3079 52.1321
B6.PWD-Chr18 m 65.4667 2.8753 71.1224 59.811
B6.PWD-Chr19 f 76.3875 3.0497 82.3863 70.3887
B6.PWD-Chr19 m 97.0125 3.0497 103.0113 91.0137
B6.PWD-Chr2 f 52.9857 3.2602 59.3987 46.5727
B6.PWD-Chr2 m 87.59 2.7277 92.9555 82.2245
B6.PWD-Chr3 f 54.775 3.0497 60.7738 48.7762
B6.PWD-Chr3 m 68.6444 2.8753 74.3002 62.9887
B6.PWD-Chr5 f 57.4571 3.2602 63.8701 51.0442
B6.PWD-Chr5 m 81.3 3.0497 87.2988 75.3012
B6.PWD-Chr6 f 64.5571 3.2602 70.9701 58.1442
B6.PWD-Chr6 m 82.95 3.0497 88.9488 76.9512
B6.PWD-Chr9 f 56.2 2.8753 61.8557 50.5443
B6.PWD-Chr9 m 75.75 3.0497 81.7488 69.7512
B6.PWD-ChrX.1 f 74.7625 3.0497 80.7613 68.7637
B6.PWD-ChrX.1 m 96.7375 3.0497 102.7363 90.7387
B6.PWD-ChrX.2 f 73.8833 3.5215 80.8101 66.9565
B6.PWD-ChrX.2 m 78.5444 2.8753 84.2002 72.8887
B6.PWD-ChrX.3 f 62.9667 4.9801 72.7626 53.1707
B6.PWD-ChrX.3 m 81.275 4.3129 89.7586 72.7914
B6.PWD-ChrY f 66.25 3.0497 72.2488 60.2512
B6.PWD-ChrY m 89.9 3.2602 96.313 83.487
B6.PWD-mt f 67.2125 3.0497 73.2113 61.2137
B6.PWD-mt m 91.8625 3.0497 97.8613 85.8637
C57BL/6J f 53.1125 3.0497 59.1113 47.1137
C57BL/6J m 68.775 2.49 73.673 63.877
PWD/PhJ f 67.4429 3.2602 73.8558 61.0299
PWD/PhJ m 85.5333 3.5215 92.4601 78.6065


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
B6.PWD-Chr1 both 79.7525 2.0458 83.7766 75.7284
B6.PWD-Chr10.1 both 66.3571 2.3053 70.8918 61.8225
B6.PWD-Chr10.2 both 59.2214 2.9762 65.0756 53.3672
B6.PWD-Chr10.3 both 57.3937 2.1564 61.6355 53.152
B6.PWD-Chr11.1 both 52.375 4.3129 60.8586 43.8914
B6.PWD-Chr11.2 both 65.9125 3.7351 73.2595 58.5655
B6.PWD-Chr11.3 both 73.4562 2.1564 77.698 69.2145
B6.PWD-Chr12 both 74.6378 1.9816 78.5357 70.7398
B6.PWD-Chr13 both 74.8875 2.1564 79.1293 70.6457
B6.PWD-Chr14 both 71.97 1.9288 75.764 68.176
B6.PWD-Chr15 both 79.7562 2.1564 83.998 75.5145
B6.PWD-Chr16 both 76.5812 2.1564 80.823 72.3395
B6.PWD-Chr17 both 83.9792 3.294 90.4586 77.4997
B6.PWD-Chr18 both 62.5933 2.4056 67.3252 57.8614
B6.PWD-Chr19 both 86.7 2.1564 90.9418 82.4582
B6.PWD-Chr2 both 70.2879 2.1254 74.4686 66.1071
B6.PWD-Chr3 both 61.7097 2.0957 65.832 57.5874
B6.PWD-Chr5 both 69.3786 2.2321 73.7692 64.9879
B6.PWD-Chr6 both 73.7536 2.2321 78.1442 69.3629
B6.PWD-Chr9 both 65.975 2.0957 70.0973 61.8527
B6.PWD-ChrX.1 both 85.75 2.1564 89.9918 81.5082
B6.PWD-ChrX.2 both 76.2139 2.2731 80.6851 71.7427
B6.PWD-ChrX.3 both 72.1208 3.294 78.6003 65.6414
B6.PWD-ChrY both 78.075 2.2321 82.4657 73.6843
B6.PWD-mt both 79.5375 2.1564 83.7793 75.2957
C57BL/6J both 60.9437 1.9686 64.816 57.0715
PWD/PhJ both 76.4881 2.3995 81.2079 71.7683




GWAS analysis not available: Strain panel must be either Inbred, HMDP, BXD, BXH, CXB, or AXB/BXA