Project measure / variable:   Finn1   saccharin

ID, description, units MPD:25604   saccharin   consumption of 0.2% saccharin in water   [mg/kg]  
Data set, strains Finn1   inbred   22 strains     sex: both     age: 11-12wks
Procedure bottle choice test
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  STRAIN COMPARISON PLOT
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Finn1 - consumption of 0.2% saccharin in water



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested22 strains22 strains
Mean of the strain means767   mg/kg 565   mg/kg
Median of the strain means820   mg/kg 596   mg/kg
SD of the strain means± 313 ± 225
Coefficient of variation (CV)0.408 0.398
Min–max range of strain means242   –   1154   mg/kg 219   –   955   mg/kg
Mean sample size per strain7.5   mice 7.9   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 3551570.4536 3551570.4536 64.7196 < 0.0001
strain 21 21731406.8477 1034828.8975 18.8575 < 0.0001
sex:strain 21 1664933.5356 79282.5493 1.4448 0.0963
Residuals 292 16023881.9813 54876.3082


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 436.0 155.0   8 54.7 0.355 261.0, 645.0 -1.06
129S1/SvImJ m 249.0 121.0   8 42.9 0.487 81.8, 449.0 -1.41
A/J f 242.0 235.0   8 83.0 0.969 8.89, 629.0 -1.68
A/J m 308.0 175.0   8 61.7 0.567 8.77, 521.0 -1.14
BALB/cByJ f 542.0 247.0   8 87.4 0.457 -0.72
BALB/cByJ m 420.0 97.0   8 34.3 0.231 210.0, 494.0 -0.65
BTBR T+ Itpr3tf/J f 352.0 81.6   8 28.9 0.232 184.0, 453.0 -1.33
BTBR T+ Itpr3tf/J m 264.0 47.3   8 16.7 0.18 209.0, 329.0 -1.34
BUB/BnJ f 482.0 138.0   3 79.5 0.285 394.0, 641.0 -0.91
BUB/BnJ m 281.0 122.0   7 46.0 0.433 89.3, 467.0 -1.26
C57BL/6J f 1072.0 107.0   8 37.7 0.0995 866.0, 1209.0 0.98
C57BL/6J m 821.0 200.0   8 70.6 0.243 538.0, 1116.0 1.14
C57BLKS/J f 890.0 232.0   8 82.0 0.26 551.0, 1227.0 0.39
C57BLKS/J m 768.0 195.0   7 73.6 0.254 408.0, 1034.0 0.9
C58/J f 1144.0 242.0   8 85.5 0.211 822.0, 1452.0 1.21
C58/J m 755.0 432.0   7 163.0 0.572 32.9, 1405.0 0.84
CZECHII/EiJ f 435.0 431.0   4 215.0 0.991 55.0, 917.0 -1.06
CZECHII/EiJ m 219.0 50.0   6 20.4 0.228 141.0, 277.0 -1.54
DBA/2J f 594.0 284.0   8 101.0 0.479 -0.55
DBA/2J m 562.0 159.0   8 56.1 0.282 237.0, 712.0 -0.01
FVB/NJ f 941.0 363.0   8 128.0 0.385 411.0, 1478.0 0.56
FVB/NJ m 631.0 325.0   8 115.0 0.515 23.2, 1000.0 0.29
I/LnJ f 1078.0 466.0   8 165.0 0.432 585.0, 1738.0 1.0
I/LnJ m 738.0 234.0   8 82.7 0.317 523.0, 1149.0 0.77
LP/J f 430.0 174.0   8 61.4 0.404 209.0, 680.0 -1.08
LP/J m 430.0 164.0   8 58.1 0.382 229.0, 699.0 -0.6
MA/MyJ f 1154.0 282.0   8 99.8 0.245 698.0, 1426.0 1.24
MA/MyJ m 680.0 113.0   8 39.9 0.166 427.0, 774.0 0.51
NOD/ShiLtJ f 1079.0 487.0   8 172.0 0.451 94.8, 1636.0 1.0
NOD/ShiLtJ m 734.0 127.0   8 44.9 0.173 467.0, 850.0 0.75
NON/ShiLtJ f 749.0 134.0   8 47.3 0.179 490.0, 955.0 -0.06
NON/ShiLtJ m 512.0 76.2   8 26.9 0.149 432.0, 656.0 -0.24
NZB/BlNJ f 641.0 80.1   8 28.3 0.125 548.0, 802.0 -0.4
NZB/BlNJ m 537.0 139.0   8 49.1 0.259 374.0, 737.0 -0.13
NZW/LacJ f 1081.0 67.9   6 27.7 0.0628 976.0, 1147.0 1.0
NZW/LacJ m 629.0 248.0   10 78.4 0.394 170.0, 1108.0 0.28
PERA/EiJ f 969.0 225.0   5 101.0 0.232 720.0, 1219.0 0.65
PERA/EiJ m 741.0 277.0   9 92.3 0.374 310.0, 1287.0 0.78
RIIIS/J f 400.0 94.7   8 33.5 0.237 201.0, 488.0 -1.17
RIIIS/J m 325.0 95.8   8 33.9 0.295 156.0, 419.0 -1.07
SEA/GnJ f 1038.0 297.0   8 105.0 0.286 500.0, 1500.0 0.87
SEA/GnJ m 878.0 118.0   8 41.8 0.135 701.0, 1047.0 1.39
SM/J f 1119.0 350.0   8 124.0 0.313 529.0, 1519.0 1.13
SM/J m 955.0 348.0   8 123.0 0.365 395.0, 1386.0 1.73


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f 436.125 82.8223 599.1294 273.1206
129S1/SvImJ m 248.975 82.8223 411.9794 85.9706
A/J f 242.2962 82.8223 405.3007 79.2918
A/J m 307.5962 82.8223 470.6007 144.5918
BALB/cByJ f 541.75 82.8223 704.7544 378.7456
BALB/cByJ m 420.0 82.8223 583.0044 256.9956
BTBR T+ Itpr3tf/J f 351.75 82.8223 514.7544 188.7456
BTBR T+ Itpr3tf/J m 263.625 82.8223 426.6294 100.6206
BUB/BnJ f 482.3333 135.2483 748.5184 216.1483
BUB/BnJ m 281.0429 88.5408 455.3019 106.7838
C57BL/6J f 1072.125 82.8223 1235.1294 909.1206
C57BL/6J m 821.0 82.8223 984.0044 657.9956
C57BLKS/J f 890.5 82.8223 1053.5044 727.4956
C57BLKS/J m 768.0 88.5408 942.259 593.741
C58/J f 1144.25 82.8223 1307.2544 981.2456
C58/J m 754.9857 88.5408 929.2448 580.7267
CZECHII/EiJ f 434.675 117.1285 665.198 204.152
CZECHII/EiJ m 218.6667 95.635 406.8879 30.4454
DBA/2J f 593.625 82.8223 756.6294 430.6206
DBA/2J m 562.125 82.8223 725.1294 399.1206
FVB/NJ f 941.25 82.8223 1104.2544 778.2456
FVB/NJ m 631.275 82.8223 794.2794 468.2706
I/LnJ f 1078.125 82.8223 1241.1294 915.1206
I/LnJ m 737.5 82.8223 900.5044 574.4956
LP/J f 429.625 82.8223 592.6294 266.6206
LP/J m 429.75 82.8223 592.7544 266.7456
MA/MyJ f 1153.75 82.8223 1316.7544 990.7456
MA/MyJ m 680.0 82.8223 843.0044 516.9956
NOD/ShiLtJ f 1079.225 82.8223 1242.2294 916.2206
NOD/ShiLtJ m 734.5 82.8223 897.5044 571.4956
NON/ShiLtJ f 749.125 82.8223 912.1294 586.1206
NON/ShiLtJ m 512.375 82.8223 675.3794 349.3706
NZB/BlNJ f 641.375 82.8223 804.3794 478.3706
NZB/BlNJ m 536.625 82.8223 699.6294 373.6206
NZW/LacJ f 1080.8333 95.635 1269.0546 892.6121
NZW/LacJ m 628.9 74.0785 774.6956 483.1044
PERA/EiJ f 969.4 104.7629 1175.5861 763.2139
PERA/EiJ m 740.7778 78.0856 894.4598 587.0958
RIIIS/J f 400.125 82.8223 563.1294 237.1206
RIIIS/J m 324.625 82.8223 487.6294 161.6206
SEA/GnJ f 1037.75 82.8223 1200.7544 874.7456
SEA/GnJ m 878.5 82.8223 1041.5044 715.4956
SM/J f 1118.625 82.8223 1281.6294 955.6206
SM/J m 954.625 82.8223 1117.6294 791.6206


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ both 342.55 58.5642 457.8115 227.2885
A/J both 274.9462 58.5642 390.2078 159.6847
BALB/cByJ both 480.875 58.5642 596.1365 365.6135
BTBR T+ Itpr3tf/J both 307.6875 58.5642 422.949 192.426
BUB/BnJ both 381.6881 80.8263 540.7641 222.6121
C57BL/6J both 946.5625 58.5642 1061.824 831.301
C57BLKS/J both 829.25 60.6197 948.557 709.943
C58/J both 949.6179 60.6197 1068.9249 830.3109
CZECHII/EiJ both 326.6708 75.6061 475.4728 177.8689
DBA/2J both 577.875 58.5642 693.1365 462.6135
FVB/NJ both 786.2625 58.5642 901.524 671.001
I/LnJ both 907.8125 58.5642 1023.074 792.551
LP/J both 429.6875 58.5642 544.949 314.426
MA/MyJ both 916.875 58.5642 1032.1365 801.6135
NOD/ShiLtJ both 906.8625 58.5642 1022.124 791.601
NON/ShiLtJ both 630.75 58.5642 746.0115 515.4885
NZB/BlNJ both 589.0 58.5642 704.2615 473.7385
NZW/LacJ both 854.8667 60.4849 973.9083 735.8251
PERA/EiJ both 855.0889 65.3311 983.6685 726.5093
RIIIS/J both 362.375 58.5642 477.6365 247.1135
SEA/GnJ both 958.125 58.5642 1073.3865 842.8635
SM/J both 1036.625 58.5642 1151.8865 921.3635




  GWAS USING LINEAR MIXED MODELS