Project measure / variable:   Mills1   RBC_micronucl_M06

ID, description, units MPD:25231   RBC_micronucl_M06   red blood cells (RBC) with micronuclei   [%]  at age 6mo  
Data set, strains Mills1   inbred   7 strains     sex: both     age: 26wks
Procedure chromosome instability assessment
Ontology mappings

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  STRAIN COMPARISON PLOT
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Mills1 - red blood cells (RBC) with micronuclei at age 6mo



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested5 strains7 strains
Mean of the strain means0.154   % 0.257   %
Median of the strain means0.158   % 0.240   %
SD of the strain means± 0.0460 ± 0.114
Coefficient of variation (CV)0.299 0.445
Min–max range of strain means0.0810   –   0.203   % 0.167   –   0.503   %
Mean sample size per strain5.6   mice 5.1   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 0.1497 0.1497 25.6802 < 0.0001
strain 4 0.0975 0.0244 4.1811 0.0061
sex:strain 4 0.1804 0.0451 7.7329 0.0001
Residuals 42 0.2449 0.0058


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
A/J m 0.167 0.0207   6 0.00843 0.124 0.14, 0.2 -0.78
AKR/J f 0.158 0.016   6 0.00654 0.101 0.15, 0.19 0.09
AKR/J m 0.18 0.0167   6 0.00683 0.093 0.16, 0.2 -0.67
BALB/cByJ f 0.203 0.0151   6 0.00615 0.074 0.18, 0.22 1.07
BALB/cByJ m 0.255 0.0259   6 0.0106 0.102 0.21, 0.28 -0.01
C57BL/6J m 0.24 0.02   6 0.00816 0.0833 0.22, 0.27 -0.15
KK/HlJ f 0.148 0.00753   6 0.00307 0.0507 0.14, 0.16 -0.13
KK/HlJ m 0.503 0.207   3 0.12 0.412 0.28, 0.69 2.15
NZO/HlLtJ f 0.18 0.00816   4 0.00408 0.0454 0.17, 0.19 0.57
NZO/HlLtJ m 0.197 0.00577   3 0.00333 0.0294 0.19, 0.2 -0.52
SM/J f 0.081 0.00576   6 0.00235 0.0711 0.071, 0.088 -1.59
SM/J m 0.255 0.174   6 0.0709 0.681 0.14, 0.59 -0.01


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
AKR/J f 0.1583 0.0312 0.2212 0.0954
AKR/J m 0.18 0.0312 0.2429 0.1171
BALB/cByJ f 0.2033 0.0312 0.2662 0.1404
BALB/cByJ m 0.255 0.0312 0.3179 0.1921
KK/HlJ f 0.1483 0.0312 0.2112 0.0854
KK/HlJ m 0.5033 0.0441 0.5923 0.4144
NZO/HlLtJ f 0.18 0.0382 0.2571 0.1029
NZO/HlLtJ m 0.1967 0.0441 0.2856 0.1077
SM/J f 0.081 0.0312 0.1439 0.0181
SM/J m 0.255 0.0312 0.3179 0.1921


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
AKR/J both 0.1692 0.022 0.2137 0.1247
BALB/cByJ both 0.2292 0.022 0.2737 0.1847
KK/HlJ both 0.3258 0.027 0.3803 0.2714
NZO/HlLtJ both 0.1883 0.0292 0.2472 0.1295
SM/J both 0.168 0.022 0.2125 0.1235




  GWAS USING LINEAR MIXED MODELS