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Project measure / variable:   Mills1   late_apoptotic_M12

ID, description, units MPD:25212   late_apoptotic_M12   late apoptotic splenocytes   [%]  at age 12mo  
Data set, strains Mills1   inbred   29 strains     sex: both     age: 52wks
Procedure apoptosis assessment
Ontology mappings

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  STRAIN COMPARISON PLOT
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Mills1 - late apoptotic splenocytes at age 12mo



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested27 strains27 strains
Mean of the strain means4.57   % 5.05   %
Median of the strain means4.43   % 5.10   %
SD of the strain means± 1.02 ± 1.07
Coefficient of variation (CV)0.223 0.212
Min–max range of strain means3.10   –   8.13   % 2.96   –   7.40   %
Mean sample size per strain3.3   mice 3.6   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 17.967 17.967 10.9888 0.0012
strain 23 106.7844 4.6428 2.8396 0.0001
sex:strain 23 54.7502 2.3804 1.4559 0.0986
Residuals 125 204.378 1.635


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 4.6 1.22   3 0.702 0.264 3.2, 5.4 0.03
129S1/SvImJ m 5.13 1.19   6 0.488 0.233 3.8, 6.5 0.07
A/J m 5.77 1.55   3 0.897 0.269 4.5, 7.5 0.67
AKR/J f 4.43 0.493   3 0.285 0.111 4.1, 5.0 -0.14
AKR/J m 3.63 0.929   3 0.536 0.256 2.6, 4.4 -1.33
BALB/cByJ f 4.67 1.12   3 0.649 0.241 3.7, 5.9 0.1
BALB/cByJ m 5.73 1.76   3 1.02 0.307 3.7, 6.8 0.63
BTBR T+ Itpr3tf/J f 3.77 2.37   3 1.37 0.63 1.6, 6.3 -0.78
BTBR T+ Itpr3tf/J m 4.76 0.979   5 0.438 0.206 3.5, 5.8 -0.27
BUB/BnJ f 3.9 0.447   6 0.183 0.115 3.4, 4.5 -0.66
BUB/BnJ m 6.65 0.354   2   0.25 0.0532 6.4, 6.9 1.49
C3H/HeJ f 4.07 0.635   3 0.367 0.156 3.7, 4.8 -0.49
C3H/HeJ m 4.05 0.354   2   0.25 0.0873 3.8, 4.3 -0.94
C57BL/10J f 5.33 0.85   6 0.347 0.159 4.1, 6.5 0.74
C57BL/10J m 5.32 0.958   5 0.428 0.18 4.2, 6.3 0.25
C57BL/6J f 4.13 0.0577   3 0.0333 0.014 4.1, 4.2 -0.43
C57BL/6J m 4.0 0.2   3 0.115 0.05 3.8, 4.2 -0.98
C57BLKS/J f 3.85 0.58   4 0.29 0.151 3.2, 4.6 -0.71
C57BLKS/J m 5.7 0.265   3 0.153 0.0464 5.5, 6.0 0.6
C57BR/cdJ f 3.4 0.5   3 0.289 0.147 2.9, 3.9 -1.15
C57BR/cdJ m 3.63 0.643   3 0.371 0.177 2.9, 4.1 -1.33
C57L/J f 5.4 1.31   3 0.757 0.243 4.2, 6.8 0.81
C57L/J m 4.43 0.493   3 0.285 0.111 4.1, 5.0 -0.58
CBA/J f 3.8 0.346   3 0.2 0.0912 3.6, 4.2 -0.75
CBA/J m 4.9 0.656   3 0.379 0.134 4.2, 5.5 -0.14
DBA/2J f 5.4 1.66   3 0.961 0.308 3.5, 6.6 0.81
DBA/2J m 7.4 3.07   6 1.25 0.415 4.9, 13.3 2.19
FVB/NJ f 4.7 0.0   3 0.0 0.0 4.7, 4.7 0.13
FVB/NJ m 5.07 1.32   3 0.762 0.261 3.9, 6.5 0.01
KK/HlJ f 3.47 0.379   3 0.219 0.109 3.2, 3.9 -1.08
KK/HlJ m 5.17 0.351   3 0.203 0.068 4.8, 5.5 0.11
LP/J f 3.57 0.569   3 0.328 0.159 3.1, 4.2 -0.98
LP/J m 4.67 0.703   6 0.287 0.151 4.0, 5.8 -0.36
MRL/MpJ f 3.1 0.753   4 0.376 0.243 2.2, 3.9 -1.44
MRL/MpJ m 2.96 0.378   5 0.169 0.128 2.4, 3.4 -1.95
NOD.B10Sn-H2b/J f 5.27 0.404   3 0.233 0.0767 4.8, 5.5 0.69
NOD.B10Sn-H2b/J m 4.03 0.757   3 0.437 0.188 3.5, 4.9 -0.95
NON/ShiLtJ f 5.37 0.231   3 0.133 0.043 5.1, 5.5 0.78
NON/ShiLtJ m 6.3 1.8   3 1.04 0.286 4.8, 8.3 1.16
NZO/HlLtJ f 8.13 1.02   3 0.59 0.126 7.4, 9.3 3.49
NZO/HlLtJ m 5.1 0.0   1   0.0 0.0 5.1, 5.1 0.04
NZW/LacJ f 4.73 0.551   3 0.318 0.116 4.2, 5.3 0.16
NZW/LacJ m 6.23 1.86   3 1.07 0.298 4.7, 8.3 1.1
P/J m 4.93 0.252   3 0.145 0.051 4.7, 5.2 -0.12
PL/J f 5.85 4.04   4 2.02 0.69 3.1, 11.8 1.25
PL/J m 3.33 0.513   3 0.296 0.154 2.9, 3.9 -1.61
PWD/PhJ f 4.63 0.981   3 0.567 0.212 3.5, 5.2 0.06
RIIIS/J f 3.87 0.569   3 0.328 0.147 3.4, 4.5 -0.69
RIIIS/J m 5.47 0.463   6 0.189 0.0848 4.8, 6.0 0.39
SJL/J f 4.3 0.9   3 0.52 0.209 3.4, 5.2 -0.26
SM/J f 5.33 1.06   3 0.612 0.199 4.2, 6.3 0.74
SM/J m 6.23 0.577   3 0.333 0.0926 5.9, 6.9 1.1
WSB/EiJ f 4.32 0.572   5 0.256 0.132 3.8, 5.1 -0.25
WSB/EiJ m 5.88 2.14   5 0.956 0.364 2.2, 7.6 0.77


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f 4.6 0.7382 6.0611 3.1389
129S1/SvImJ m 5.1333 0.522 6.1665 4.1002
AKR/J f 4.4333 0.7382 5.8944 2.9723
AKR/J m 3.6333 0.7382 5.0944 2.1723
BALB/cByJ f 4.6667 0.7382 6.1277 3.2056
BALB/cByJ m 5.7333 0.7382 7.1944 4.2723
BTBR T+ Itpr3tf/J f 3.7667 0.7382 5.2277 2.3056
BTBR T+ Itpr3tf/J m 4.76 0.5718 5.8917 3.6283
BUB/BnJ f 3.9 0.522 4.9331 2.8669
BUB/BnJ m 6.65 0.9042 8.4395 4.8605
C3H/HeJ f 4.0667 0.7382 5.5277 2.6056
C3H/HeJ m 4.05 0.9042 5.8395 2.2605
C57BL/10J f 5.3333 0.522 6.3665 4.3002
C57BL/10J m 5.32 0.5718 6.4517 4.1883
C57BL/6J f 4.1333 0.7382 5.5944 2.6723
C57BL/6J m 4.0 0.7382 5.4611 2.5389
C57BLKS/J f 3.85 0.6393 5.1153 2.5847
C57BLKS/J m 5.7 0.7382 7.1611 4.2389
C57BR/cdJ f 3.4 0.7382 4.8611 1.9389
C57BR/cdJ m 3.6333 0.7382 5.0944 2.1723
C57L/J f 5.4 0.7382 6.8611 3.9389
C57L/J m 4.4333 0.7382 5.8944 2.9723
CBA/J f 3.8 0.7382 5.2611 2.3389
CBA/J m 4.9 0.7382 6.3611 3.4389
DBA/2J f 5.4 0.7382 6.8611 3.9389
DBA/2J m 7.4 0.522 8.4331 6.3669
FVB/NJ f 4.7 0.7382 6.1611 3.2389
FVB/NJ m 5.0667 0.7382 6.5277 3.6056
KK/HlJ f 3.4667 0.7382 4.9277 2.0056
KK/HlJ m 5.1667 0.7382 6.6277 3.7056
LP/J f 3.5667 0.7382 5.0277 2.1056
LP/J m 4.6667 0.522 5.6998 3.6335
MRL/MpJ f 3.1 0.6393 4.3653 1.8347
MRL/MpJ m 2.96 0.5718 4.0917 1.8283
NOD.B10Sn-H2b/J f 5.2667 0.7382 6.7277 3.8056
NOD.B10Sn-H2b/J m 4.0333 0.7382 5.4944 2.5723
NON/ShiLtJ f 5.3667 0.7382 6.8277 3.9056
NON/ShiLtJ m 6.3 0.7382 7.7611 4.8389
NZW/LacJ f 4.7333 0.7382 6.1944 3.2723
NZW/LacJ m 6.2333 0.7382 7.6944 4.7723
PL/J f 5.85 0.6393 7.1153 4.5847
PL/J m 3.3333 0.7382 4.7944 1.8723
RIIIS/J f 3.8667 0.7382 5.3277 2.4056
RIIIS/J m 5.4667 0.522 6.4998 4.4335
SM/J f 5.3333 0.7382 6.7944 3.8723
SM/J m 6.2333 0.7382 7.6944 4.7723
WSB/EiJ f 4.32 0.5718 5.4517 3.1883
WSB/EiJ m 5.88 0.5718 7.0117 4.7483


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ both 4.8667 0.4521 5.7614 3.9719
AKR/J both 4.0333 0.522 5.0665 3.0002
BALB/cByJ both 5.2 0.522 6.2331 4.1669
BTBR T+ Itpr3tf/J both 4.2633 0.4669 5.1874 3.3393
BUB/BnJ both 5.275 0.522 6.3081 4.2419
C3H/HeJ both 4.0583 0.5836 5.2134 2.9032
C57BL/10J both 5.3267 0.3871 6.0929 4.5605
C57BL/6J both 4.0667 0.522 5.0998 3.0335
C57BLKS/J both 4.775 0.4883 5.7414 3.8086
C57BR/cdJ both 3.5167 0.522 4.5498 2.4835
C57L/J both 4.9167 0.522 5.9498 3.8835
CBA/J both 4.35 0.522 5.3831 3.3169
DBA/2J both 6.4 0.4521 7.2947 5.5053
FVB/NJ both 4.8833 0.522 5.9165 3.8502
KK/HlJ both 4.3167 0.522 5.3498 3.2835
LP/J both 4.1167 0.4521 5.0114 3.2219
MRL/MpJ both 3.03 0.4289 3.8788 2.1812
NOD.B10Sn-H2b/J both 4.65 0.522 5.6831 3.6169
NON/ShiLtJ both 5.8333 0.522 6.8665 4.8002
NZW/LacJ both 5.4833 0.522 6.5165 4.4502
PL/J both 4.5917 0.4883 5.5581 3.6253
RIIIS/J both 4.6667 0.4521 5.5614 3.7719
SM/J both 5.7833 0.522 6.8165 4.7502
WSB/EiJ both 5.1 0.4044 5.9003 4.2997




  GWAS USING LINEAR MIXED MODELS