Project measure / variable:   Xing1   HR_M12

ID, description, units MPD:24902   HR_M12   heart rate   [n/min]  at age 12mo  
Data set, strains Xing1   inbred   28 strains     sex: both     age: 52wks
Procedure ECG
Ontology mappings

  STRAIN COMPARISON PLOT
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Xing1 - heart rate at age 12mo



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested27 strains27 strains
Mean of the strain means718   n/min 732   n/min
Median of the strain means711   n/min 735   n/min
SD of the strain means± 29.7 ± 32.6
Coefficient of variation (CV)0.0414 0.0445
Min–max range of strain means657   –   776   n/min 664   –   795   n/min
Mean sample size per strain7.5   mice 7.5   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 14484.3939 14484.3939 8.8591 0.0031
strain 25 280612.62 11224.5048 6.8652 < 0.0001
sex:strain 25 79281.4166 3171.2567 1.9396 0.0051
Residuals 337 550987.7032 1634.9783


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 690.0 26.5   8 9.37 0.0384 663.0, 747.0 -0.95
129S1/SvImJ m 730.0 33.9   8 12.0 0.0465 672.0, 768.0 -0.07
A/J f 715.0 48.1   7 18.2 0.0673 629.0, 773.0 -0.11
A/J m 687.0 65.8   7 24.9 0.0957 611.0, 761.0 -1.39
AKR/J f 702.0 171.0   4 85.6 0.244 448.0, 805.0 -0.54
AKR/J m 795.0 18.1   5 8.08 0.0227 767.0, 811.0 1.92
BALB/cByJ f 711.0 41.1   6 16.8 0.0578 666.0, 771.0 -0.24
BALB/cByJ m 682.0 30.6   8 10.8 0.0449 612.0, 714.0 -1.54
BTBR T+ Itpr3tf/J f 750.0 37.3   8 13.2 0.0498 691.0, 818.0 1.07
BTBR T+ Itpr3tf/J m 752.0 34.4   8 12.2 0.0457 688.0, 787.0 0.6
BUB/BnJ f 763.0 25.3   7 9.57 0.0332 717.0, 791.0 1.51
BUB/BnJ m 779.0 24.4   8 8.62 0.0313 743.0, 808.0 1.43
C3H/HeJ f 776.0 24.0   8 8.49 0.031 722.0, 799.0 1.94
C3H/HeJ m 788.0 43.2   8 15.3 0.0548 723.0, 837.0 1.71
C57BL/10J f 703.0 32.2   8 11.4 0.0458 647.0, 748.0 -0.51
C57BL/10J m 734.0 29.7   8 10.5 0.0405 688.0, 776.0 0.05
C57BL/6J f 727.0 24.6   7 9.28 0.0338 691.0, 761.0 0.3
C57BL/6J m 741.0 19.1   8 6.76 0.0258 711.0, 767.0 0.27
C57BLKS/J f 710.0 26.2   8 9.27 0.0369 674.0, 742.0 -0.28
C57BLKS/J m 735.0 40.7   8 14.4 0.0554 651.0, 786.0 0.08
C57BR/cdJ f 737.0 27.8   6 11.4 0.0378 700.0, 763.0 0.63
C57BR/cdJ m 744.0 9.77   8 3.45 0.0131 730.0, 762.0 0.36
C57L/J f 686.0 23.1   7 8.72 0.0336 661.0, 731.0 -1.08
C57L/J m 712.0 34.0   8 12.0 0.0477 654.0, 774.0 -0.62
CBA/J f 718.0 43.1   8 15.2 0.06 653.0, 765.0 -0.01
CBA/J m 727.0 52.0   7 19.6 0.0715 651.0, 791.0 -0.16
DBA/2J f 704.0 17.8   7 6.75 0.0253 679.0, 724.0 -0.48
DBA/2J m 734.0 53.9   8 19.1 0.0734 636.0, 804.0 0.05
FVB/NJ f 707.0 61.0   8 21.6 0.0863 611.0, 789.0 -0.38
FVB/NJ m 741.0 56.5   8 20.0 0.0763 657.0, 806.0 0.27
KK/HlJ f 719.0 16.5   8 5.83 0.023 704.0, 748.0 0.03
KK/HlJ m 745.0 16.8   9 5.59 0.0225 716.0, 765.0 0.39
LP/J f 754.0 34.8   7 13.1 0.0462 707.0, 793.0 1.2
LP/J m 740.0 42.6   8 15.1 0.0576 665.0, 777.0 0.24
MRL/MpJ f 702.0 21.0   7 7.94 0.0299 667.0, 729.0 -0.54
MRL/MpJ m 717.0 62.1   6 25.4 0.0866 646.0, 815.0 -0.47
NOD.B10Sn-H2b/J f 775.0 25.4   10 8.04 0.0328 737.0, 809.0 1.91
NOD.B10Sn-H2b/J m 784.0 31.3   8 11.1 0.04 744.0, 828.0 1.59
NON/ShiLtJ f 698.0 26.8   7 10.1 0.0384 677.0, 753.0 -0.68
NON/ShiLtJ m 691.0 29.8   8 10.6 0.0432 648.0, 742.0 -1.27
NZO/HlLtJ f 711.0 47.2   9 15.7 0.0664 626.0, 780.0 -0.24
NZO/HlLtJ m 684.0 42.9   5 19.2 0.0628 621.0, 737.0 -1.48
NZW/LacJ f 693.0 58.9   8 20.8 0.085 568.0, 757.0 -0.85
NZW/LacJ m 664.0 39.5   7 14.9 0.0595 589.0, 711.0 -2.09
P/J m 738.0 36.3   6 14.8 0.0492 684.0, 769.0 0.17
PL/J f 702.0 39.1   8 13.8 0.0558 667.0, 767.0 -0.54
PL/J m 713.0 30.5   7 11.5 0.0428 678.0, 749.0 -0.59
RIIIS/J f 657.0 69.8   7 26.4 0.106 547.0, 768.0 -2.06
RIIIS/J m 744.0 17.3   8 6.12 0.0233 722.0, 768.0 0.36
SJL/J f 680.0 67.6   8 23.9 0.0993 545.0, 755.0 -1.28
SM/J f 752.0 34.1   7 12.9 0.0454 695.0, 792.0 1.14
SM/J m 748.0 25.8   8 9.14 0.0346 692.0, 782.0 0.48
SWR/J f 749.0 24.3   8 8.59 0.0324 693.0, 773.0 1.04
SWR/J m 723.0 35.5   7 13.4 0.0491 662.0, 759.0 -0.29


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f 689.5 14.2959 717.6204 661.3796
129S1/SvImJ m 729.75 14.2959 757.8704 701.6296
A/J f 715.0 15.2829 745.062 684.938
A/J m 686.8571 15.2829 716.9191 656.7952
AKR/J f 702.25 20.2174 742.0183 662.4817
AKR/J m 795.4 18.083 830.9698 759.8302
BALB/cByJ f 710.8333 16.5075 743.304 678.3627
BALB/cByJ m 682.125 14.2959 710.2454 654.0046
BTBR T+ Itpr3tf/J f 749.75 14.2959 777.8704 721.6296
BTBR T+ Itpr3tf/J m 752.0 14.2959 780.1204 723.8796
BUB/BnJ f 763.0 15.2829 793.062 732.938
BUB/BnJ m 778.625 14.2959 806.7454 750.5046
C3H/HeJ f 776.125 14.2959 804.2454 748.0046
C3H/HeJ m 788.25 14.2959 816.3704 760.1296
C57BL/10J f 703.25 14.2959 731.3704 675.1296
C57BL/10J m 734.0 14.2959 762.1204 705.8796
C57BL/6J f 727.4286 15.2829 757.4906 697.3666
C57BL/6J m 741.375 14.2959 769.4954 713.2546
C57BLKS/J f 710.0 14.2959 738.1204 681.8796
C57BLKS/J m 735.25 14.2959 763.3704 707.1296
C57BR/cdJ f 737.0 16.5075 769.4707 704.5293
C57BR/cdJ m 743.625 14.2959 771.7454 715.5046
C57L/J f 686.0 15.2829 716.062 655.938
C57L/J m 712.375 14.2959 740.4954 684.2546
CBA/J f 718.0 14.2959 746.1204 689.8796
CBA/J m 727.0 15.2829 757.062 696.938
DBA/2J f 704.1429 15.2829 734.2048 674.0809
DBA/2J m 734.5 14.2959 762.6204 706.3796
FVB/NJ f 707.25 14.2959 735.3704 679.1296
FVB/NJ m 740.875 14.2959 768.9954 712.7546
KK/HlJ f 718.625 14.2959 746.7454 690.5046
KK/HlJ m 744.7778 13.4783 771.29 718.2656
LP/J f 753.5714 15.2829 783.6334 723.5094
LP/J m 739.875 14.2959 767.9954 711.7546
MRL/MpJ f 701.7143 15.2829 731.7763 671.6523
MRL/MpJ m 717.0 16.5075 749.4707 684.5293
NOD.B10Sn-H2b/J f 774.9 12.7866 800.0517 749.7483
NOD.B10Sn-H2b/J m 784.25 14.2959 812.3704 756.1296
NON/ShiLtJ f 697.7143 15.2829 727.7763 667.6523
NON/ShiLtJ m 691.125 14.2959 719.2454 663.0046
NZO/HlLtJ f 711.3333 13.4783 737.8455 684.8212
NZO/HlLtJ m 684.0 18.083 719.5698 648.4302
NZW/LacJ f 693.25 14.2959 721.3704 665.1296
NZW/LacJ m 664.0 15.2829 694.062 633.938
PL/J f 702.0 14.2959 730.1204 673.8796
PL/J m 713.2857 15.2829 743.3477 683.2237
RIIIS/J f 657.0 15.2829 687.062 626.938
RIIIS/J m 744.25 14.2959 772.3704 716.1296
SM/J f 752.2857 15.2829 782.3477 722.2237
SM/J m 747.5 14.2959 775.6204 719.3796
SWR/J f 748.75 14.2959 776.8704 720.6296
SWR/J m 722.8571 15.2829 752.9191 692.7952


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ both 709.625 10.1087 729.5091 689.7409
A/J both 700.9286 10.8067 722.1856 679.6715
AKR/J both 748.825 13.5623 775.5024 722.1476
BALB/cByJ both 696.4792 10.9187 717.9565 675.0019
BTBR T+ Itpr3tf/J both 750.875 10.1087 770.7591 730.9909
BUB/BnJ both 770.8125 10.4635 791.3945 750.2305
C3H/HeJ both 782.1875 10.1087 802.0716 762.3034
C57BL/10J both 718.625 10.1087 738.5091 698.7409
C57BL/6J both 734.4018 10.4635 754.9838 713.8198
C57BLKS/J both 722.625 10.1087 742.5091 702.7409
C57BR/cdJ both 740.3125 10.9187 761.7898 718.8352
C57L/J both 699.1875 10.4635 719.7695 678.6055
CBA/J both 722.5 10.4635 743.082 701.918
DBA/2J both 719.3214 10.4635 739.9035 698.7394
FVB/NJ both 724.0625 10.1087 743.9466 704.1784
KK/HlJ both 731.7014 9.8239 751.0253 712.3775
LP/J both 746.7232 10.4635 767.3052 726.1412
MRL/MpJ both 709.3571 11.2479 731.4822 687.2321
NOD.B10Sn-H2b/J both 779.575 9.59 798.4387 760.7113
NON/ShiLtJ both 694.4196 10.4635 715.0017 673.8376
NZO/HlLtJ both 697.6667 11.2767 719.8483 675.485
NZW/LacJ both 678.625 10.4635 699.207 658.043
PL/J both 707.6429 10.4635 728.2249 687.0608
RIIIS/J both 700.625 10.4635 721.207 680.043
SM/J both 749.8929 10.4635 770.4749 729.3108
SWR/J both 735.8036 10.4635 756.3856 715.2215




  GWAS USING LINEAR MIXED MODELS