Project measure / variable:   Yuan3   BUN_M18

ID, description, units MPD:24483   BUN_M18   blood urea nitrogen (plasma BUN)   [mg/dL]  at age 18mo  
Data set, strains Yuan3   inbred   29 strains     sex: both     age: 78wks
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  STRAIN COMPARISON PLOT
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Yuan3 - blood urea nitrogen (plasma BUN) at age 18mo



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested29 strains25 strains
Mean of the strain means24.1   mg/dL 24.9   mg/dL
Median of the strain means22.6   mg/dL 24.8   mg/dL
SD of the strain means± 5.37 ± 4.75
Coefficient of variation (CV)0.223 0.190
Min–max range of strain means17.5   –   40.0   mg/dL 16.7   –   34.1   mg/dL
Mean sample size per strain6.3   mice 5.4   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 28.1576 28.1576 1.688 0.1951
strain 22 5588.1776 254.0081 15.2277 < 0.0001
sex:strain 22 1396.5477 63.4794 3.8056 < 0.0001
Residuals 241 4020.0369 16.6807


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 19.5 3.11   4 1.55 0.159 17.0, 24.0 -0.85
129S1/SvImJ m 27.8 3.92   6 1.6 0.141 24.0, 35.0 0.6
A/J f 24.3 5.13   6 2.09 0.211 19.0, 32.0 0.05
BALB/cByJ f 27.1 3.76   7 1.42 0.139 21.0, 32.0 0.57
BALB/cByJ m 25.2 3.19   5 1.43 0.127 21.0, 30.0 0.06
BTBR T+ Itpr3tf/J f 22.1 5.94   8 2.1 0.268 13.0, 31.0 -0.36
BTBR T+ Itpr3tf/J m 21.2 1.48   5 0.663 0.07 19.0, 23.0 -0.79
BUB/BnJ f 29.1 3.4   8 1.2 0.117 24.0, 33.0 0.94
BUB/BnJ m 23.0 3.1   6 1.26 0.135 17.0, 26.0 -0.41
C3H/HeJ f 26.1 4.05   8 1.43 0.155 21.0, 32.0 0.38
C3H/HeJ m 23.4 4.43   7 1.67 0.189 20.0, 33.0 -0.32
C57BL/10J f 30.8 6.3   5 2.82 0.205 23.0, 40.0 1.26
C57BL/10J m 23.0 0.0   1   0.0 0.0 23.0, 23.0 -0.41
C57BL/6J f 22.7 2.63   7 0.993 0.116 19.0, 25.0 -0.25
C57BL/6J m 26.1 4.63   7 1.75 0.177 23.0, 36.0 0.25
C57BLKS/J f 20.4 2.57   7 0.972 0.126 16.0, 24.0 -0.68
C57BR/cdJ f 17.6 2.2   8 0.778 0.125 15.0, 21.0 -1.2
C57BR/cdJ m 21.5 2.26   6 0.922 0.105 20.0, 26.0 -0.72
C57L/J f 19.0 3.51   7 1.33 0.185 14.0, 22.0 -0.94
C57L/J m 18.8 2.14   6 0.872 0.113 16.0, 21.0 -1.29
CBA/J f 24.6 4.27   8 1.51 0.174 18.0, 30.0 0.1
CBA/J m 21.7 1.63   6 0.667 0.0754 19.0, 24.0 -0.68
DBA/2J f 22.6 5.09   7 1.93 0.226 13.0, 29.0 -0.27
DBA/2J m 32.8 2.68   5 1.2 0.0818 30.0, 36.0 1.66
FVB/NJ f 21.4 3.58   8 1.27 0.168 16.0, 27.0 -0.49
KK/HlJ f 19.0 3.46   3 2.0 0.182 15.0, 21.0 -0.94
KK/HlJ m 20.2 3.54   6 1.45 0.176 16.0, 24.0 -1.0
LP/J f 19.3 1.15   3 0.667 0.0597 18.0, 20.0 -0.89
LP/J m 26.2 1.79   5 0.8 0.0683 24.0, 28.0 0.27
MRL/MpJ f 21.7 6.53   6 2.67 0.301 11.0, 30.0 -0.44
MRL/MpJ m 21.1 3.56   8 1.26 0.169 16.0, 25.0 -0.81
NOD.B10Sn-H2b/J f 21.0 1.41   7 0.535 0.0673 19.0, 23.0 -0.57
NOD.B10Sn-H2b/J m 25.0 2.45   4 1.22 0.098 23.0, 28.0 0.01
NON/ShiLtJ f 32.1 7.28   14 1.95 0.227 24.0, 44.0 1.5
NON/ShiLtJ m 33.5 3.94   6 1.61 0.118 28.0, 38.0 1.8
NZO/HlLtJ f 25.5 2.12   2   1.5 0.0832 24.0, 27.0 0.27
NZW/LacJ f 21.3 5.13   6 2.09 0.24 12.0, 26.0 -0.51
NZW/LacJ m 27.4 4.08   7 1.54 0.149 24.0, 35.0 0.52
P/J f 40.0 11.3   2   8.0 0.283 32.0, 48.0 2.97
P/J m 24.8 3.77   4 1.89 0.153 21.0, 28.0 -0.03
PL/J f 21.5 3.67   6 1.5 0.171 17.0, 27.0 -0.48
PL/J m 20.6 4.56   5 2.04 0.221 17.0, 28.0 -0.91
PWD/PhJ f 28.7 2.36   7 0.892 0.0822 26.0, 32.0 0.86
PWD/PhJ m 34.1 2.61   7 0.986 0.0764 30.0, 38.0 1.93
RIIIS/J f 26.4 6.13   7 2.32 0.232 22.0, 40.0 0.44
RIIIS/J m 27.2 3.87   6 1.58 0.142 24.0, 34.0 0.48
SJL/J f 23.4 3.2   8 1.13 0.137 18.0, 27.0 -0.12
SJL/J m 26.0 5.57   3 3.21 0.214 20.0, 31.0 0.22
SM/J f 34.4 4.65   7 1.76 0.135 28.0, 42.0 1.93
SM/J m 34.0 4.64   5 2.07 0.136 29.0, 40.0 1.91
SWR/J f 17.5 2.12   2   1.5 0.121 16.0, 19.0 -1.22
SWR/J m 22.0 0.0   1   0.0 0.0 22.0, 22.0 -0.62
WSB/EiJ f 18.5 2.0   8 0.707 0.108 15.0, 22.0 -1.03
WSB/EiJ m 16.7 1.63   6 0.667 0.098 15.0, 19.0 -1.73


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f 19.5 2.0421 23.5226 15.4774
129S1/SvImJ m 27.8333 1.6674 31.1178 24.5489
BALB/cByJ f 27.1429 1.5437 30.1837 24.102
BALB/cByJ m 25.2 1.8265 28.798 21.602
BTBR T+ Itpr3tf/J f 22.125 1.444 24.9694 19.2806
BTBR T+ Itpr3tf/J m 21.2 1.8265 24.798 17.602
BUB/BnJ f 29.125 1.444 31.9694 26.2806
BUB/BnJ m 23.0 1.6674 26.2845 19.7155
C3H/HeJ f 26.125 1.444 28.9694 23.2806
C3H/HeJ m 23.4286 1.5437 26.4694 20.3877
C57BL/6J f 22.7143 1.5437 25.7551 19.6735
C57BL/6J m 26.1429 1.5437 29.1837 23.102
C57BR/cdJ f 17.625 1.444 20.4694 14.7806
C57BR/cdJ m 21.5 1.6674 24.7845 18.2155
C57L/J f 19.0 1.5437 22.0408 15.9592
C57L/J m 18.8333 1.6674 22.1178 15.5489
CBA/J f 24.625 1.444 27.4694 21.7806
CBA/J m 21.6667 1.6674 24.9511 18.3822
DBA/2J f 22.5714 1.5437 25.6123 19.5306
DBA/2J m 32.8 1.8265 36.398 29.202
KK/HlJ f 19.0 2.358 23.6449 14.3551
KK/HlJ m 20.1667 1.6674 23.4511 16.8822
LP/J f 19.3333 2.358 23.9783 14.6884
LP/J m 26.2 1.8265 29.798 22.602
MRL/MpJ f 21.6667 1.6674 24.9511 18.3822
MRL/MpJ m 21.125 1.444 23.9694 18.2806
NOD.B10Sn-H2b/J f 21.0 1.5437 24.0408 17.9592
NOD.B10Sn-H2b/J m 25.0 2.0421 29.0226 20.9774
NON/ShiLtJ f 32.0714 1.0915 34.2216 29.9212
NON/ShiLtJ m 33.5 1.6674 36.7845 30.2155
NZW/LacJ f 21.3333 1.6674 24.6178 18.0489
NZW/LacJ m 27.4286 1.5437 30.4694 24.3877
P/J f 40.0 2.888 45.6889 34.3111
P/J m 24.75 2.0421 28.7726 20.7274
PL/J f 21.5 1.6674 24.7845 18.2155
PL/J m 20.6 1.8265 24.198 17.002
PWD/PhJ f 28.7143 1.5437 31.7551 25.6735
PWD/PhJ m 34.1429 1.5437 37.1837 31.102
RIIIS/J f 26.4286 1.5437 29.4694 23.3877
RIIIS/J m 27.1667 1.6674 30.4511 23.8822
SJL/J f 23.375 1.444 26.2194 20.5306
SJL/J m 26.0 2.358 30.6449 21.3551
SM/J f 34.4286 1.5437 37.4694 31.3877
SM/J m 34.0 1.8265 37.598 30.402
WSB/EiJ f 18.5 1.444 21.3444 15.6556
WSB/EiJ m 16.6667 1.6674 19.9511 13.3822


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ both 23.6667 1.3182 26.2633 21.0701
BALB/cByJ both 26.1714 1.1957 28.5268 23.816
BTBR T+ Itpr3tf/J both 21.6625 1.1642 23.9558 19.3692
BUB/BnJ both 26.0625 1.1029 28.235 23.89
C3H/HeJ both 24.7768 1.0569 26.8587 22.6949
C57BL/6J both 24.4286 1.0915 26.5788 22.2784
C57BR/cdJ both 19.5625 1.1029 21.735 17.39
C57L/J both 18.9167 1.1361 21.1547 16.6787
CBA/J both 23.1458 1.1029 25.3183 20.9734
DBA/2J both 27.6857 1.1957 30.0411 25.3303
KK/HlJ both 19.5833 1.444 22.4278 16.7389
LP/J both 22.7667 1.4913 25.7044 19.8289
MRL/MpJ both 21.3958 1.1029 23.5683 19.2234
NOD.B10Sn-H2b/J both 23.0 1.28 25.5213 20.4787
NON/ShiLtJ both 32.7857 0.9964 34.7486 30.8229
NZW/LacJ both 24.381 1.1361 26.6189 22.143
P/J both 32.375 1.7685 35.8587 28.8913
PL/J both 21.05 1.2366 23.4858 18.6142
PWD/PhJ both 31.4286 1.0915 33.5788 29.2784
RIIIS/J both 26.7976 1.1361 29.0356 24.5596
SJL/J both 24.6875 1.3825 27.4108 21.9642
SM/J both 34.2143 1.1957 36.5697 31.8589
WSB/EiJ both 17.5833 1.1029 19.7558 15.4109




  GWAS USING LINEAR MIXED MODELS