Project measure / variable:   Yuan3   CO2_M12

ID, description, units MPD:24462   CO2_M12   dissolved-ionized carbon dioxide (CO2)   [mmol/L]  at age 12mo  
Data set, strains Yuan3   inbred   31 strains     sex: both     age: 52wks
Procedure metabolic panel
Ontology mappings

  STRAIN COMPARISON PLOT
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Yuan3 - dissolved-ionized carbon dioxide (CO2) at age 12mo



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested31 strains29 strains
Mean of the strain means19.7   mmol/L 18.2   mmol/L
Median of the strain means19.2   mmol/L 18.8   mmol/L
SD of the strain means± 3.41 ± 3.17
Coefficient of variation (CV)0.173 0.174
Min–max range of strain means12.5   –   25.1   mmol/L 10.7   –   23.5   mmol/L
Mean sample size per strain7.2   mice 7.4   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 373.3339 373.3339 43.7321 < 0.0001
strain 28 3468.2305 123.8654 14.5095 < 0.0001
sex:strain 28 1151.8466 41.1374 4.8188 < 0.0001
Residuals 363 3098.8744 8.5368


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
Select table page:
Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 17.5 1.27   8 0.45 0.0729 15.4, 19.2 -0.65
129S1/SvImJ m 21.4 1.94   8 0.685 0.0905 18.3, 23.9 1.01
A/J f 21.5 2.23   6 0.908 0.104 17.1, 22.9 0.52
A/J m 13.2 2.44   16 0.611 0.185 7.0, 15.6 -1.57
AKR/J f 23.3 1.7   2   1.2 0.0728 22.1, 24.5 1.05
AKR/J m 21.2 3.06   3 1.77 0.145 17.7, 23.5 0.95
BALB/cByJ f 23.4 4.16   8 1.47 0.178 15.3, 28.1 1.08
BALB/cByJ m 17.6 2.68   8 0.948 0.153 13.0, 20.4 -0.19
BTBR T+ Itpr3tf/J f 17.9 2.85   8 1.01 0.159 14.6, 23.0 -0.53
BTBR T+ Itpr3tf/J m 18.8 1.87   7 0.708 0.0996 16.0, 22.2 0.19
BUB/BnJ f 23.0 1.09   6 0.446 0.0476 21.7, 24.5 0.96
BUB/BnJ m 18.9 2.09   9 0.696 0.111 17.1, 23.5 0.22
C3H/HeJ f 22.3 1.23   8 0.437 0.0554 20.5, 24.3 0.76
C3H/HeJ m 17.7 3.09   7 1.17 0.174 11.3, 19.9 -0.16
C57BL/10J f 18.9 2.42   8 0.856 0.128 16.5, 23.1 -0.24
C57BL/10J m 16.3 1.5   7 0.565 0.0917 14.2, 18.0 -0.6
C57BL/6J f 19.2 1.59   8 0.561 0.0826 16.9, 21.5 -0.15
C57BL/6J m 20.4 1.29   8 0.457 0.0633 18.5, 22.5 0.7
C57BLKS/J f 21.9 2.44   8 0.862 0.111 18.3, 25.3 0.64
C57BLKS/J m 17.3 1.78   8 0.629 0.103 14.2, 19.6 -0.28
C57BR/cdJ f 18.9 2.28   8 0.806 0.121 14.7, 21.9 -0.24
C57BR/cdJ m 13.0 2.99   8 1.06 0.229 8.8, 16.4 -1.64
C57L/J f 20.7 3.77   7 1.43 0.183 13.9, 23.3 0.29
C57L/J m 18.9 3.84   8 1.36 0.204 11.3, 22.5 0.22
CAST/EiJ f 15.2 2.13   8 0.753 0.14 12.5, 18.7 -1.33
CBA/J f 18.3 1.17   7 0.442 0.0638 16.5, 19.5 -0.42
CBA/J m 19.0 1.76   6 0.72 0.0927 15.5, 20.3 0.25
DBA/2J f 18.9 3.63   5 1.62 0.192 13.1, 23.1 -0.24
DBA/2J m 19.9 2.58   7 0.974 0.13 17.1, 24.1 0.54
FVB/NJ f 13.5 2.92   8 1.03 0.216 7.6, 16.2 -1.83
FVB/NJ m 16.1 5.24   8 1.85 0.326 8.0, 25.4 -0.66
KK/HlJ f 23.4 1.96   8 0.693 0.0838 21.5, 27.5 1.08
KK/HlJ m 18.6 2.61   8 0.924 0.14 14.0, 22.2 0.13
LP/J f 22.9 3.29   7 1.24 0.144 19.1, 27.1 0.93
LP/J m 22.3 1.48   8 0.522 0.0663 20.4, 24.4 1.3
MRL/MpJ f 25.1 1.93   8 0.681 0.0769 21.4, 27.8 1.58
MRL/MpJ m 19.0 3.67   8 1.3 0.194 12.8, 25.2 0.25
NOD.B10Sn-H2b/J f 20.2 1.14   6 0.465 0.0564 18.8, 21.8 0.14
NOD.B10Sn-H2b/J m 19.8 1.04   7 0.394 0.0527 18.2, 21.2 0.51
NON/ShiLtJ f 12.5 3.3   7 1.25 0.265 8.8, 17.4 -2.12
NON/ShiLtJ m 15.0 5.28   7 2.0 0.352 9.1, 23.5 -1.01
NZO/HlLtJ f 18.2 3.43   7 1.3 0.189 12.4, 23.2 -0.45
NZO/HlLtJ m 20.3 6.18   6 2.52 0.305 10.0, 25.7 0.66
NZW/LacJ f 24.4 3.99   8 1.41 0.164 15.1, 28.5 1.37
NZW/LacJ m 23.4 2.92   8 1.03 0.125 19.5, 29.3 1.64
P/J f 20.7 2.85   8 1.01 0.138 17.3, 23.9 0.29
PL/J f 17.7 9.02   3 5.21 0.509 7.3, 23.3 -0.59
PL/J m 21.0 2.09   5 0.935 0.0995 18.5, 24.3 0.89
PWD/PhJ f 24.0 1.53   8 0.542 0.0638 21.9, 26.1 1.26
PWD/PhJ m 23.5 3.95   8 1.4 0.168 16.9, 29.1 1.67
RIIIS/J f 15.5 1.06   7 0.399 0.0684 14.0, 17.4 -1.24
RIIIS/J m 12.7 3.27   8 1.16 0.258 9.6, 19.6 -1.73
SJL/J f 23.7 3.03   6 1.24 0.128 20.1, 28.1 1.17
SJL/J m 18.7 1.65   4 0.823 0.088 16.6, 20.6 0.16
SM/J f 16.5 1.29   7 0.488 0.0783 14.8, 18.4 -0.95
SM/J m 16.0 2.85   9 0.951 0.178 11.1, 20.0 -0.69
SWR/J f 16.9 3.99   9 1.33 0.236 11.4, 22.0 -0.83
SWR/J m 10.7 3.38   7 1.28 0.314 7.0, 17.2 -2.36
WSB/EiJ f 15.3 2.53   7 0.955 0.165 10.3, 18.1 -1.3
WSB/EiJ m 16.9 3.16   7 1.19 0.187 10.5, 19.7 -0.41


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f 17.475 1.033 19.5064 15.4436
129S1/SvImJ m 21.4 1.033 23.4314 19.3686
A/J f 21.4667 1.1928 23.8124 19.121
A/J m 13.175 0.7304 14.6114 11.7386
AKR/J f 23.3 2.066 27.3629 19.2371
AKR/J m 21.1667 1.6869 24.484 17.8494
BALB/cByJ f 23.35 1.033 25.3814 21.3186
BALB/cByJ m 17.55 1.033 19.5814 15.5186
BTBR T+ Itpr3tf/J f 17.9 1.033 19.9314 15.8686
BTBR T+ Itpr3tf/J m 18.8 1.1043 20.9717 16.6283
BUB/BnJ f 22.9667 1.1928 25.3124 20.621
BUB/BnJ m 18.8778 0.9739 20.793 16.9625
C3H/HeJ f 22.275 1.033 24.3064 20.2436
C3H/HeJ m 17.7286 1.1043 19.9003 15.5569
C57BL/10J f 18.925 1.033 20.9564 16.8936
C57BL/10J m 16.3143 1.1043 18.486 14.1426
C57BL/6J f 19.2 1.033 21.2314 17.1686
C57BL/6J m 20.4 1.033 22.4314 18.3686
C57BLKS/J f 21.95 1.033 23.9814 19.9186
C57BLKS/J m 17.3 1.033 19.3314 15.2686
C57BR/cdJ f 18.9 1.033 20.9314 16.8686
C57BR/cdJ m 13.025 1.033 15.0564 10.9936
C57L/J f 20.6714 1.1043 22.8431 18.4997
C57L/J m 18.85 1.033 20.8814 16.8186
CBA/J f 18.3286 1.1043 20.5003 16.1569
CBA/J m 19.0333 1.1928 21.379 16.6876
DBA/2J f 18.9 1.3067 21.4696 16.3304
DBA/2J m 19.8714 1.1043 22.0431 17.6997
FVB/NJ f 13.5 1.033 15.5314 11.4686
FVB/NJ m 16.1 1.033 18.1314 14.0686
KK/HlJ f 23.375 1.033 25.4064 21.3436
KK/HlJ m 18.65 1.033 20.6814 16.6186
LP/J f 22.8714 1.1043 25.0431 20.6997
LP/J m 22.275 1.033 24.3064 20.2436
MRL/MpJ f 25.05 1.033 27.0814 23.0186
MRL/MpJ m 18.975 1.033 21.0064 16.9436
NOD.B10Sn-H2b/J f 20.2 1.1928 22.5457 17.8543
NOD.B10Sn-H2b/J m 19.7714 1.1043 21.9431 17.5997
NON/ShiLtJ f 12.4571 1.1043 14.6288 10.2855
NON/ShiLtJ m 14.9857 1.1043 17.1574 12.814
NZO/HlLtJ f 18.2 1.1043 20.3717 16.0283
NZO/HlLtJ m 20.2833 1.1928 22.629 17.9376
NZW/LacJ f 24.35 1.033 26.3814 22.3186
NZW/LacJ m 23.425 1.033 25.4564 21.3936
PL/J f 17.7 1.6869 21.0173 14.3827
PL/J m 21.02 1.3067 23.5896 18.4504
PWD/PhJ f 24.05 1.033 26.0814 22.0186
PWD/PhJ m 23.525 1.033 25.5564 21.4936
RIIIS/J f 15.4571 1.1043 17.6288 13.2855
RIIIS/J m 12.675 1.033 14.7064 10.6436
SJL/J f 23.6667 1.1928 26.0124 21.321
SJL/J m 18.7 1.4609 21.5729 15.8271
SM/J f 16.4857 1.1043 18.6574 14.314
SM/J m 16.0444 0.9739 17.9597 14.1292
SWR/J f 16.9111 0.9739 18.8264 14.9959
SWR/J m 10.7429 1.1043 12.9145 8.5712
WSB/EiJ f 15.3286 1.1043 17.5003 13.1569
WSB/EiJ m 16.8714 1.1043 19.0431 14.6997


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ both 19.4375 0.7304 20.8739 18.0011
A/J both 17.3208 0.6993 18.6961 15.9455
AKR/J both 22.2333 1.3336 24.8559 19.6108
BALB/cByJ both 20.45 0.7304 21.8864 19.0136
BTBR T+ Itpr3tf/J both 18.35 0.7561 19.8369 16.8631
BUB/BnJ both 20.9222 0.77 22.4364 19.4081
C3H/HeJ both 20.0018 0.7561 21.4886 18.5149
C57BL/10J both 17.6196 0.7561 19.1065 16.1328
C57BL/6J both 19.8 0.7304 21.2364 18.3636
C57BLKS/J both 19.625 0.7304 21.0614 18.1886
C57BR/cdJ both 15.9625 0.7304 17.3989 14.5261
C57L/J both 19.7607 0.7561 21.2476 18.2739
CBA/J both 18.681 0.8128 20.2793 17.0826
DBA/2J both 19.3857 0.8554 21.0679 17.7035
FVB/NJ both 14.8 0.7304 16.2364 13.3636
KK/HlJ both 21.0125 0.7304 22.4489 19.5761
LP/J both 22.5732 0.7561 24.0601 21.0864
MRL/MpJ both 22.0125 0.7304 23.4489 20.5761
NOD.B10Sn-H2b/J both 19.9857 0.8128 21.584 18.3874
NON/ShiLtJ both 13.7214 0.7809 15.257 12.1858
NZO/HlLtJ both 19.2417 0.8128 20.84 17.6433
NZW/LacJ both 23.8875 0.7304 25.3239 22.4511
PL/J both 19.36 1.0669 21.4581 17.2619
PWD/PhJ both 23.7875 0.7304 25.2239 22.3511
RIIIS/J both 14.0661 0.7561 15.5529 12.5792
SJL/J both 21.1833 0.943 23.0378 19.3289
SM/J both 16.2651 0.7362 17.7129 14.8173
SWR/J both 13.827 0.7362 15.2748 12.3792
WSB/EiJ both 16.1 0.7809 17.6356 14.5644




  GWAS USING LINEAR MIXED MODELS