Project measure / variable:   Yuan3   Fe_M06

ID, description, units MPD:24426   Fe_M06   iron (serum Fe)   [mmol/L]  at age 6mo  
Data set, strains Yuan3   inbred   30 strains     sex: both     age: 26wks
Procedure metabolic panel
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  STRAIN COMPARISON PLOT
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Yuan3 - iron (serum Fe) at age 6mo



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested28 strains25 strains
Mean of the strain means247   mmol/L 227   mmol/L
Median of the strain means246   mmol/L 228   mmol/L
SD of the strain means± 41.2 ± 44.7
Coefficient of variation (CV)0.167 0.197
Min–max range of strain means156   –   343   mmol/L 124   –   317   mmol/L
Mean sample size per strain7.6   mice 7.3   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 57550.3245 57550.3245 56.5968 < 0.0001
strain 22 427430.4495 19428.6568 19.1068 < 0.0001
sex:strain 22 129270.3886 5875.9268 5.7786 < 0.0001
Residuals 313 318273.2998 1016.8476


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 263.0 34.5   6 14.1 0.131 211.0, 289.0 0.4
129S1/SvImJ m 210.0 17.2   7 6.51 0.082 190.0, 232.0 -0.38
A/J f 273.0 29.8   16 7.45 0.109 226.0, 349.0 0.64
A/J m 263.0 22.2   8 7.86 0.0846 230.0, 295.0 0.81
BALB/cByJ f 253.0 26.3   8 9.3 0.104 227.0, 297.0 0.15
BALB/cByJ m 241.0 20.7   8 7.33 0.0859 211.0, 264.0 0.32
BTBR T+ Itpr3tf/J f 285.0 15.4   4 7.72 0.0542 270.0, 306.0 0.93
BTBR T+ Itpr3tf/J m 248.0 11.8   8 4.18 0.0477 233.0, 267.0 0.47
BUB/BnJ f 251.0 129.0   3 74.6 0.514 136.0, 391.0 0.11
BUB/BnJ m 308.0 49.4   6 20.2 0.161 259.0, 370.0 1.81
C3H/HeJ f 228.0 20.5   8 7.23 0.0898 197.0, 253.0 -0.45
C3H/HeJ m 231.0 17.6   7 6.66 0.0763 206.0, 253.0 0.09
C57BL/10J f 206.0 25.8   8 9.12 0.125 173.0, 248.0 -0.99
C57BL/10J m 148.0 14.2   8 5.04 0.0963 120.0, 167.0 -1.76
C57BL/6J f 156.0 48.2   8 17.0 0.309 115.0, 251.0 -2.2
C57BL/6J m 124.0 7.0   4 3.5 0.0562 116.0, 132.0 -2.3
C57BLKS/J f 196.0 31.4   8 11.1 0.16 156.0, 234.0 -1.23
C57BLKS/J m 173.0 14.0   7 5.3 0.0812 158.0, 191.0 -1.2
C57BR/cdJ m 225.0 12.3   3 7.13 0.0548 215.0, 239.0 -0.04
C57L/J f 263.0 30.0   8 10.6 0.114 230.0, 322.0 0.4
C57L/J m 221.0 24.9   8 8.79 0.112 175.0, 247.0 -0.13
CAST/EiJ f 198.0 10.4   4 5.19 0.0523 185.0, 210.0 -1.18
CBA/J f 206.0 21.7   6 8.85 0.105 181.0, 244.0 -0.99
DBA/2J f 248.0 51.9   8 18.3 0.209 183.0, 335.0 0.03
DBA/2J m 227.0 23.8   16 5.94 0.105 198.0, 267.0 0.0
FVB/NJ f 343.0 45.8   14 12.2 0.134 227.0, 400.0 2.34
FVB/NJ m 241.0 30.8   9 10.3 0.128 191.0, 303.0 0.32
KK/HlJ f 343.0 67.6   7 25.6 0.197 233.0, 420.0 2.34
LP/J f 310.0 41.1   8 14.5 0.133 259.0, 355.0 1.54
LP/J m 231.0 23.5   8 8.3 0.102 189.0, 267.0 0.09
MOLF/EiJ f 229.0 47.8   7 18.1 0.209 165.0, 283.0 -0.43
MOLF/EiJ m 188.0 23.1   7 8.75 0.123 157.0, 215.0 -0.87
MRL/MpJ m 317.0 38.3   8 13.6 0.121 241.0, 352.0 2.02
NOD.B10Sn-H2b/J f 261.0 38.0   9 12.7 0.145 207.0, 343.0 0.35
NOD.B10Sn-H2b/J m 205.0 8.89   5 3.97 0.0434 194.0, 214.0 -0.49
NON/ShiLtJ f 223.0 21.0   8 7.44 0.0943 197.0, 268.0 -0.57
NON/ShiLtJ m 260.0 24.7   8 8.72 0.095 220.0, 293.0 0.74
NZO/HlLtJ f 229.0 34.2   8 12.1 0.149 147.0, 258.0 -0.43
NZO/HlLtJ m 217.0 45.6   6 18.6 0.211 159.0, 262.0 -0.22
NZW/LacJ f 239.0 56.0   8 19.8 0.235 175.0, 339.0 -0.19
P/J f 264.0 42.3   8 15.0 0.16 227.0, 335.0 0.42
P/J m 228.0 21.7   8 7.68 0.0951 188.0, 253.0 0.03
PL/J f 253.0 25.8   10 8.16 0.102 222.0, 300.0 0.15
PL/J m 262.0 38.8   9 12.9 0.148 167.0, 295.0 0.79
PWD/PhJ f 232.0 25.6   8 9.06 0.11 210.0, 290.0 -0.36
PWD/PhJ m 212.0 22.8   7 8.62 0.107 179.0, 244.0 -0.33
RIIIS/J f 213.0 23.2   6 9.45 0.109 180.0, 239.0 -0.82
RIIIS/J m 267.0 15.2   8 5.37 0.0569 240.0, 294.0 0.9
SJL/J f 232.0 46.3   8 16.4 0.199 178.0, 315.0 -0.36
SM/J f 245.0 12.8   8 4.54 0.0523 226.0, 265.0 -0.04
SM/J m 165.0 37.1   7 14.0 0.225 106.0, 211.0 -1.38
WSB/EiJ f 264.0 20.5   5 9.18 0.0777 243.0, 292.0 0.42
WSB/EiJ m 259.0 24.6   6 10.0 0.095 224.0, 291.0 0.72


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f 262.8333 13.0182 288.4477 237.219
129S1/SvImJ m 209.8571 12.0525 233.5714 186.1429
A/J f 273.375 7.972 289.0605 257.6895
A/J m 262.75 11.2741 284.9327 240.5673
BALB/cByJ f 253.25 11.2741 275.4327 231.0673
BALB/cByJ m 241.375 11.2741 263.5577 219.1923
BTBR T+ Itpr3tf/J f 284.75 15.944 316.121 253.379
BTBR T+ Itpr3tf/J m 247.75 11.2741 269.9327 225.5673
BUB/BnJ f 251.3333 18.4106 287.5575 215.1092
BUB/BnJ m 307.6667 13.0182 333.281 282.0523
C3H/HeJ f 227.625 11.2741 249.8077 205.4423
C3H/HeJ m 231.0 12.0525 254.7143 207.2857
C57BL/10J f 206.5 11.2741 228.6827 184.3173
C57BL/10J m 147.875 11.2741 170.0577 125.6923
C57BL/6J f 156.0 11.2741 178.1827 133.8173
C57BL/6J m 124.5 15.944 155.871 93.129
C57BLKS/J f 196.5 11.2741 218.6827 174.3173
C57BLKS/J m 172.7143 12.0525 196.4285 149.0
C57L/J f 263.125 11.2741 285.3077 240.9423
C57L/J m 221.0 11.2741 243.1827 198.8173
DBA/2J f 248.25 11.2741 270.4327 226.0673
DBA/2J m 226.5625 7.972 242.248 210.877
FVB/NJ f 342.7857 8.5224 359.5542 326.0172
FVB/NJ m 241.3333 10.6293 262.2473 220.4193
LP/J f 309.75 11.2741 331.9327 287.5673
LP/J m 231.0 11.2741 253.1827 208.8173
MOLF/EiJ f 228.5714 12.0525 252.2857 204.8572
MOLF/EiJ m 187.7143 12.0525 211.4285 164.0
NOD.B10Sn-H2b/J f 261.1111 10.6293 282.0251 240.1971
NOD.B10Sn-H2b/J m 205.0 14.2608 233.0591 176.9409
NON/ShiLtJ f 223.125 11.2741 245.3077 200.9423
NON/ShiLtJ m 259.625 11.2741 281.8077 237.4423
NZO/HlLtJ f 229.125 11.2741 251.3077 206.9423
NZO/HlLtJ m 216.6667 13.0182 242.281 191.0523
P/J f 264.25 11.2741 286.4327 242.0673
P/J m 228.375 11.2741 250.5577 206.1923
PL/J f 253.2 10.0839 273.0408 233.3592
PL/J m 261.7778 10.6293 282.6918 240.8638
PWD/PhJ f 232.375 11.2741 254.5577 210.1923
PWD/PhJ m 212.2857 12.0525 236.0 188.5715
RIIIS/J f 213.3333 13.0182 238.9477 187.719
RIIIS/J m 266.75 11.2741 288.9327 244.5673
SM/J f 245.25 11.2741 267.4327 223.0673
SM/J m 164.7143 12.0525 188.4285 141.0
WSB/EiJ f 264.2 14.2608 292.2591 236.1409
WSB/EiJ m 259.0 13.0182 284.6143 233.3857


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ both 236.3452 8.8704 253.7985 218.892
A/J both 268.0625 6.904 281.6465 254.4785
BALB/cByJ both 247.3125 7.972 262.998 231.627
BTBR T+ Itpr3tf/J both 266.25 9.7637 285.4607 247.0393
BUB/BnJ both 279.5 11.2741 301.6827 257.3173
C3H/HeJ both 229.3125 8.2518 245.5485 213.0765
C57BL/10J both 177.1875 7.972 192.873 161.502
C57BL/6J both 140.25 9.7637 159.4607 121.0393
C57BLKS/J both 184.6071 8.2518 200.8432 168.3711
C57L/J both 242.0625 7.972 257.748 226.377
DBA/2J both 237.4063 6.904 250.9903 223.8222
FVB/NJ both 292.0595 6.812 305.4627 278.6564
LP/J both 270.375 7.972 286.0605 254.6895
MOLF/EiJ both 208.1429 8.5224 224.9114 191.3743
NOD.B10Sn-H2b/J both 233.0556 8.8932 250.5535 215.5576
NON/ShiLtJ both 241.375 7.972 257.0605 225.6895
NZO/HlLtJ both 222.8958 8.6108 239.8381 205.9535
P/J both 246.3125 7.972 261.998 230.627
PL/J both 257.4889 7.3258 271.9029 243.0749
PWD/PhJ both 222.3304 8.2518 238.5664 206.0943
RIIIS/J both 240.0417 8.6108 256.984 223.0994
SM/J both 204.9821 8.2518 221.2182 188.7461
WSB/EiJ both 261.6 9.6546 280.5961 242.6039




  GWAS USING LINEAR MIXED MODELS