Project measure / variable:   Yuan3   ALP_M12

ID, description, units MPD:24412   ALP_M12   alkaline phosphatase (serum ALP)   [IU/L]  at age 12mo  
Data set, strains Yuan3   inbred   31 strains     sex: both     age: 52wks
Procedure metabolic panel
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  STRAIN COMPARISON PLOT
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Yuan3 - alkaline phosphatase (serum ALP) at age 12mo



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested31 strains29 strains
Mean of the strain means118   IU/L 78.3   IU/L
Median of the strain means104   IU/L 79.0   IU/L
SD of the strain means± 82.9 ± 32.6
Coefficient of variation (CV)0.705 0.417
Min–max range of strain means35.2   –   507   IU/L 37.6   –   186   IU/L
Mean sample size per strain7.1   mice 7.2   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 162825.4688 162825.4688 115.6122 < 0.0001
strain 28 1019429.0048 36408.1787 25.8512 < 0.0001
sex:strain 28 641405.2002 22907.3286 16.2651 < 0.0001
Residuals 355 499973.5272 1408.3761


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
Select table page:
Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 117.0 25.5   8 9.03 0.219 82.0, 143.0 -0.01
129S1/SvImJ m 51.9 16.7   8 5.89 0.321 34.0, 85.0 -0.81
A/J f 68.3 16.6   6 6.76 0.242 50.0, 95.0 -0.59
A/J m 85.1 10.5   16 2.63 0.124 71.0, 113.0 0.21
AKR/J f 75.5 4.95   2   3.5 0.0656 72.0, 79.0 -0.51
AKR/J m 69.0 16.6   3 9.61 0.241 57.0, 88.0 -0.29
BALB/cByJ f 77.1 16.8   8 5.93 0.217 51.0, 97.0 -0.49
BALB/cByJ m 80.1 24.6   8 8.7 0.307 30.0, 104.0 0.05
BTBR T+ Itpr3tf/J f 64.5 18.1   8 6.41 0.281 50.0, 103.0 -0.64
BTBR T+ Itpr3tf/J m 71.9 22.2   7 8.38 0.309 43.0, 102.0 -0.2
BUB/BnJ f 142.0 39.2   6 16.0 0.276 102.0, 188.0 0.29
BUB/BnJ m 83.8 18.2   9 6.08 0.218 63.0, 114.0 0.17
C3H/HeJ f 113.0 31.0   8 11.0 0.274 61.0, 167.0 -0.06
C3H/HeJ m 77.6 7.14   7 2.7 0.092 66.0, 88.0 -0.02
C57BL/10J f 151.0 59.7   7 22.6 0.394 32.0, 206.0 0.4
C57BL/10J m 86.1 18.8   7 7.09 0.218 59.0, 102.0 0.24
C57BL/6J f 129.0 41.8   8 14.8 0.324 86.0, 200.0 0.14
C57BL/6J m 83.5 10.2   8 3.61 0.122 70.0, 97.0 0.16
C57BLKS/J f 85.4 22.7   8 8.04 0.266 36.0, 114.0 -0.39
C57BLKS/J m 79.4 6.78   8 2.4 0.0854 70.0, 91.0 0.03
C57BR/cdJ f 63.9 13.8   8 4.87 0.216 47.0, 90.0 -0.65
C57BR/cdJ m 73.4 7.39   8 2.61 0.101 62.0, 83.0 -0.15
C57L/J f 47.7 7.67   7 2.9 0.161 39.0, 60.0 -0.84
C57L/J m 39.4 3.85   8 1.36 0.0978 34.0, 47.0 -1.19
CAST/EiJ f 116.0 41.4   8 14.7 0.356 86.0, 207.0 -0.02
CBA/J f 106.0 18.3   7 6.93 0.173 88.0, 141.0 -0.14
CBA/J m 71.8 22.0   6 8.97 0.306 28.0, 85.0 -0.2
DBA/2J f 127.0 32.9   4 16.4 0.259 83.0, 161.0 0.11
DBA/2J m 85.1 9.3   7 3.51 0.109 71.0, 102.0 0.21
FVB/NJ f 120.0 38.9   8 13.8 0.324 82.0, 204.0 0.03
FVB/NJ m 54.9 6.31   8 2.23 0.115 44.0, 61.0 -0.72
KK/HlJ f 507.0 217.0   7 81.9 0.427 206.0, 804.0 4.7
KK/HlJ m 89.8 11.9   8 4.2 0.132 70.0, 102.0 0.35
LP/J f 137.0 39.8   7 15.1 0.291 81.0, 204.0 0.23
LP/J m 40.4 4.96   8 1.75 0.123 33.0, 49.0 -1.16
MRL/MpJ f 185.0 58.9   8 20.8 0.318 81.0, 268.0 0.81
MRL/MpJ m 152.0 39.1   8 13.8 0.257 108.0, 212.0 2.26
NOD.B10Sn-H2b/J f 58.2 12.3   6 5.02 0.211 49.0, 82.0 -0.72
NOD.B10Sn-H2b/J m 37.6 2.44   7 0.922 0.0649 33.0, 41.0 -1.25
NON/ShiLtJ f 35.2 9.13   8 3.23 0.259 23.0, 54.0 -0.99
NON/ShiLtJ m 41.4 23.0   7 8.68 0.554 26.0, 93.0 -1.13
NZO/HlLtJ f 70.4 13.6   7 5.13 0.193 54.0, 98.0 -0.57
NZO/HlLtJ m 48.3 13.7   6 5.58 0.283 28.0, 69.0 -0.92
NZW/LacJ f 99.1 39.0   8 13.8 0.393 33.0, 163.0 -0.22
NZW/LacJ m 79.1 22.4   8 7.92 0.283 64.0, 130.0 0.02
P/J f 88.0 27.6   8 9.75 0.313 45.0, 127.0 -0.36
PL/J f 140.0 18.5   3 10.7 0.132 119.0, 152.0 0.27
PL/J m 129.0 20.7   5 9.26 0.161 107.0, 163.0 1.55
PWD/PhJ f 182.0 31.2   8 11.0 0.172 133.0, 229.0 0.78
PWD/PhJ m 186.0 44.2   8 15.6 0.238 101.0, 244.0 3.3
RIIIS/J f 80.2 10.7   8 3.78 0.133 64.0, 95.0 -0.45
RIIIS/J m 79.0 11.6   8 4.1 0.147 52.0, 89.0 0.02
SJL/J f 60.5 8.8   6 3.59 0.146 49.0, 70.0 -0.69
SJL/J m 46.2 5.56   4 2.78 0.12 41.0, 54.0 -0.98
SM/J f 104.0 10.5   7 3.95 0.101 87.0, 117.0 -0.16
SM/J m 95.4 38.7   9 12.9 0.405 59.0, 185.0 0.52
SWR/J f 98.3 21.5   7 8.13 0.219 63.0, 123.0 -0.23
SWR/J m 66.1 16.7   7 6.31 0.253 37.0, 88.0 -0.37
WSB/EiJ f 197.0 38.7   7 14.6 0.196 141.0, 242.0 0.96
WSB/EiJ m 88.0 12.7   2   9.0 0.145 79.0, 97.0 0.3


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f 116.875 13.2683 142.9693 90.7807
129S1/SvImJ m 51.875 13.2683 77.9693 25.7807
A/J f 68.3333 15.3209 98.4644 38.2022
A/J m 85.0625 9.3821 103.514 66.611
AKR/J f 75.5 26.5365 127.6886 23.3114
AKR/J m 69.0 21.667 111.6118 26.3882
BALB/cByJ f 77.125 13.2683 103.2193 51.0307
BALB/cByJ m 80.125 13.2683 106.2193 54.0307
BTBR T+ Itpr3tf/J f 64.5 13.2683 90.5943 38.4057
BTBR T+ Itpr3tf/J m 71.8571 14.1844 99.7531 43.9612
BUB/BnJ f 142.1667 15.3209 172.2978 112.0356
BUB/BnJ m 83.7778 12.5094 108.3797 59.1758
C3H/HeJ f 113.125 13.2683 139.2193 87.0307
C3H/HeJ m 77.5714 14.1844 105.4674 49.6755
C57BL/10J f 151.4286 14.1844 179.3245 123.5326
C57BL/10J m 86.1429 14.1844 114.0388 58.2469
C57BL/6J f 128.875 13.2683 154.9693 102.7807
C57BL/6J m 83.5 13.2683 109.5943 57.4057
C57BLKS/J f 85.375 13.2683 111.4693 59.2807
C57BLKS/J m 79.375 13.2683 105.4693 53.2807
C57BR/cdJ f 63.875 13.2683 89.9693 37.7807
C57BR/cdJ m 73.375 13.2683 99.4693 47.2807
C57L/J f 47.7143 14.1844 75.6103 19.8183
C57L/J m 39.375 13.2683 65.4693 13.2807
CBA/J f 106.2857 14.1844 134.1817 78.3897
CBA/J m 71.8333 15.3209 101.9644 41.7022
DBA/2J f 126.75 18.7642 163.6529 89.8471
DBA/2J m 85.1429 14.1844 113.0388 57.2469
FVB/NJ f 120.25 13.2683 146.3443 94.1557
FVB/NJ m 54.875 13.2683 80.9693 28.7807
KK/HlJ f 506.8571 14.1844 534.7531 478.9612
KK/HlJ m 89.75 13.2683 115.8443 63.6557
LP/J f 136.7143 14.1844 164.6103 108.8183
LP/J m 40.375 13.2683 66.4693 14.2807
MRL/MpJ f 184.875 13.2683 210.9693 158.7807
MRL/MpJ m 152.375 13.2683 178.4693 126.2807
NOD.B10Sn-H2b/J f 58.1667 15.3209 88.2978 28.0356
NOD.B10Sn-H2b/J m 37.5714 14.1844 65.4674 9.6755
NON/ShiLtJ f 35.25 13.2683 61.3443 9.1557
NON/ShiLtJ m 41.4286 14.1844 69.3245 13.5326
NZO/HlLtJ f 70.4286 14.1844 98.3245 42.5326
NZO/HlLtJ m 48.3333 15.3209 78.4644 18.2022
NZW/LacJ f 99.125 13.2683 125.2193 73.0307
NZW/LacJ m 79.125 13.2683 105.2193 53.0307
PL/J f 140.3333 21.667 182.9451 97.7215
PL/J m 128.8 16.7832 161.807 95.793
PWD/PhJ f 181.75 13.2683 207.8443 155.6557
PWD/PhJ m 185.875 13.2683 211.9693 159.7807
RIIIS/J f 80.25 13.2683 106.3443 54.1557
RIIIS/J m 79.0 13.2683 105.0943 52.9057
SJL/J f 60.5 15.3209 90.6311 30.3689
SJL/J m 46.25 18.7642 83.1529 9.3471
SM/J f 104.0 14.1844 131.896 76.104
SM/J m 95.4444 12.5094 120.0464 70.8425
SWR/J f 98.2857 14.1844 126.1817 70.3897
SWR/J m 66.1429 14.1844 94.0388 38.2469
WSB/EiJ f 197.1429 14.1844 225.0388 169.2469
WSB/EiJ m 88.0 26.5365 140.1886 35.8114


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ both 84.375 9.3821 102.8265 65.9235
A/J both 76.6979 8.9827 94.3638 59.032
AKR/J both 72.25 17.1293 105.9376 38.5624
BALB/cByJ both 78.625 9.3821 97.0765 60.1735
BTBR T+ Itpr3tf/J both 68.1786 9.7114 87.2776 49.0795
BUB/BnJ both 112.9722 9.8896 132.4218 93.5227
C3H/HeJ both 95.3482 9.7114 114.4473 76.2491
C57BL/10J both 118.7857 10.0299 138.5111 99.0603
C57BL/6J both 106.1875 9.3821 124.639 87.736
C57BLKS/J both 82.375 9.3821 100.8265 63.9235
C57BR/cdJ both 68.625 9.3821 87.0765 50.1735
C57L/J both 43.5446 9.7114 62.6437 24.4456
CBA/J both 89.0595 10.4394 109.5904 68.5286
DBA/2J both 105.9464 11.7611 129.0765 82.8163
FVB/NJ both 87.5625 9.3821 106.014 69.111
KK/HlJ both 298.3036 9.7114 317.4026 279.2045
LP/J both 88.5446 9.7114 107.6437 69.4456
MRL/MpJ both 168.625 9.3821 187.0765 150.1735
NOD.B10Sn-H2b/J both 47.869 10.4394 68.3999 27.3382
NON/ShiLtJ both 38.3393 9.7114 57.4384 19.2402
NZO/HlLtJ both 59.381 10.4394 79.9118 38.8501
NZW/LacJ both 89.125 9.3821 107.5765 70.6735
PL/J both 134.5667 13.7034 161.5167 107.6166
PWD/PhJ both 183.8125 9.3821 202.264 165.361
RIIIS/J both 79.625 9.3821 98.0765 61.1735
SJL/J both 53.375 12.1122 77.1957 29.5543
SM/J both 99.7222 9.4563 118.3195 81.1249
SWR/J both 82.2143 10.0299 101.9397 62.4889
WSB/EiJ both 142.5714 15.0448 172.1596 112.9833




  GWAS USING LINEAR MIXED MODELS