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Project measure / variable:   Yuan3   ALP_M06

ID, description, units MPD:24411   ALP_M06   alkaline phosphatase (serum ALP)   [IU/L]  at age 6mo  
Data set, strains Yuan3   inbred   30 strains     sex: both     age: 26wks
Procedure metabolic panel
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  STRAIN COMPARISON PLOT
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Yuan3 - alkaline phosphatase (serum ALP) at age 6mo



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested28 strains25 strains
Mean of the strain means96.5   IU/L 74.5   IU/L
Median of the strain means89.4   IU/L 68.2   IU/L
SD of the strain means± 41.9 ± 38.3
Coefficient of variation (CV)0.434 0.514
Min–max range of strain means31.0   –   249   IU/L 34.1   –   190   IU/L
Mean sample size per strain7.8   mice 7.4   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 26406.4288 26406.4288 106.815 < 0.0001
strain 22 375591.0323 17072.3197 69.0582 < 0.0001
sex:strain 22 45079.5919 2049.0724 8.2886 < 0.0001
Residuals 323 79850.8982 247.2164


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
Select table page:
Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 90.4 12.0   5 5.35 0.132 71.0, 102.0 -0.15
129S1/SvImJ m 45.2 18.9   8 6.67 0.417 30.0, 87.0 -0.77
A/J f 83.2 15.5   16 3.87 0.186 64.0, 125.0 -0.32
A/J m 73.8 12.5   8 4.43 0.17 61.0, 97.0 -0.02
BALB/cByJ f 88.5 9.44   8 3.34 0.107 75.0, 103.0 -0.19
BALB/cByJ m 78.1 3.44   8 1.22 0.044 74.0, 84.0 0.09
BTBR T+ Itpr3tf/J f 53.8 7.37   4 3.68 0.137 45.0, 63.0 -1.02
BTBR T+ Itpr3tf/J m 39.0 3.07   8 1.09 0.0787 34.0, 44.0 -0.93
BUB/BnJ f 89.2 25.4   6 10.4 0.284 68.0, 139.0 -0.17
BUB/BnJ m 76.8 9.41   6 3.84 0.122 61.0, 84.0 0.06
C3H/HeJ f 83.6 15.5   8 5.49 0.186 69.0, 119.0 -0.31
C3H/HeJ m 67.4 3.46   7 1.31 0.0513 61.0, 71.0 -0.19
C57BL/10J f 151.0 34.7   8 12.3 0.23 109.0, 196.0 1.3
C57BL/10J m 82.4 10.9   8 3.85 0.132 70.0, 99.0 0.21
C57BL/6J f 95.1 23.2   8 8.21 0.244 65.0, 143.0 -0.03
C57BL/6J m 68.2 3.95   4 1.97 0.0578 65.0, 73.0 -0.17
C57BLKS/J f 89.6 25.6   8 9.04 0.285 33.0, 116.0 -0.16
C57BLKS/J m 66.9 8.36   8 2.95 0.125 58.0, 83.0 -0.2
C57BR/cdJ m 41.5 1.91   4 0.957 0.0461 40.0, 44.0 -0.86
C57L/J f 46.9 3.91   8 1.38 0.0834 42.0, 53.0 -1.18
C57L/J m 42.8 4.98   8 1.76 0.116 36.0, 51.0 -0.83
CAST/EiJ f 101.0 36.8   4 18.4 0.365 47.0, 130.0 0.11
CBA/J f 101.0 13.3   6 5.41 0.131 82.0, 123.0 0.11
DBA/2J f 104.0 11.9   8 4.21 0.114 87.0, 118.0 0.18
DBA/2J m 93.3 7.64   16 1.91 0.0819 78.0, 105.0 0.49
FVB/NJ f 86.8 10.7   14 2.86 0.123 66.0, 103.0 -0.23
FVB/NJ m 46.7 6.14   9 2.05 0.132 36.0, 56.0 -0.73
KK/HlJ f 249.0 72.9   8 25.8 0.293 151.0, 392.0 3.64
LP/J f 83.8 11.5   8 4.08 0.138 61.0, 93.0 -0.3
LP/J m 41.4 6.67   8 2.36 0.161 31.0, 53.0 -0.87
MOLF/EiJ f 150.0 12.8   7 4.84 0.0856 135.0, 167.0 1.28
MOLF/EiJ m 159.0 26.6   7 10.0 0.167 140.0, 214.0 2.2
MRL/MpJ m 106.0 11.4   8 4.02 0.107 89.0, 127.0 0.82
NOD.B10Sn-H2b/J f 66.3 9.81   9 3.27 0.148 55.0, 85.0 -0.72
NOD.B10Sn-H2b/J m 39.0 7.48   7 2.83 0.192 29.0, 49.0 -0.93
NON/ShiLtJ f 31.0 2.14   8 0.756 0.069 28.0, 34.0 -1.56
NON/ShiLtJ m 34.1 4.58   8 1.62 0.134 26.0, 40.0 -1.06
NZO/HlLtJ f 54.5 11.2   8 3.95 0.205 29.0, 65.0 -1.0
NZO/HlLtJ m 54.2 11.8   6 4.83 0.218 40.0, 70.0 -0.53
NZW/LacJ f 71.4 7.46   8 2.64 0.105 61.0, 83.0 -0.6
P/J f 90.5 47.1   8 16.7 0.521 62.0, 205.0 -0.14
P/J m 51.8 7.17   8 2.53 0.138 40.0, 62.0 -0.59
PL/J f 129.0 22.8   10 7.2 0.177 97.0, 174.0 0.78
PL/J m 127.0 19.6   9 6.53 0.154 84.0, 158.0 1.37
PWD/PhJ f 154.0 10.1   8 3.58 0.0657 143.0, 169.0 1.37
PWD/PhJ m 190.0 26.2   7 9.89 0.138 155.0, 233.0 3.01
RIIIS/J f 80.3 11.1   7 4.21 0.139 67.0, 96.0 -0.39
RIIIS/J m 96.5 11.9   8 4.19 0.123 69.0, 109.0 0.57
SJL/J f 70.6 7.37   8 2.6 0.104 62.0, 83.0 -0.62
SM/J f 97.2 12.0   8 4.25 0.124 74.0, 115.0 0.02
SM/J m 69.0 11.6   7 4.38 0.168 53.0, 89.0 -0.14
WSB/EiJ f 110.0 11.3   8 4.01 0.103 99.0, 129.0 0.32
WSB/EiJ m 73.5 16.8   6 6.85 0.228 54.0, 94.0 -0.03


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f 90.4 7.0316 104.2335 76.5665
129S1/SvImJ m 45.25 5.559 56.1863 34.3137
A/J f 83.25 3.9308 90.9832 75.5168
A/J m 73.75 5.559 84.6863 62.8137
BALB/cByJ f 88.5 5.559 99.4363 77.5637
BALB/cByJ m 78.125 5.559 89.0613 67.1887
BTBR T+ Itpr3tf/J f 53.75 7.8616 69.2163 38.2837
BTBR T+ Itpr3tf/J m 39.0 5.559 49.9363 28.0637
BUB/BnJ f 89.1667 6.4189 101.7949 76.5385
BUB/BnJ m 76.8333 6.4189 89.4615 64.2051
C3H/HeJ f 83.625 5.559 94.5613 72.6887
C3H/HeJ m 67.4286 5.9428 79.12 55.7371
C57BL/10J f 151.0 5.559 161.9363 140.0637
C57BL/10J m 82.375 5.559 93.3113 71.4387
C57BL/6J f 95.125 5.559 106.0613 84.1887
C57BL/6J m 68.25 7.8616 83.7163 52.7837
C57BLKS/J f 89.625 5.559 100.5613 78.6887
C57BLKS/J m 66.875 5.559 77.8113 55.9387
C57L/J f 46.875 5.559 57.8113 35.9387
C57L/J m 42.75 5.559 53.6863 31.8137
DBA/2J f 104.5 5.559 115.4363 93.5637
DBA/2J m 93.3125 3.9308 101.0457 85.5793
FVB/NJ f 86.7857 4.2022 95.0528 78.5186
FVB/NJ m 46.6667 5.241 56.9775 36.3558
LP/J f 83.75 5.559 94.6863 72.8137
LP/J m 41.375 5.559 52.3113 30.4387
MOLF/EiJ f 149.5714 5.9428 161.2629 137.88
MOLF/EiJ m 158.5714 5.9428 170.2629 146.88
NOD.B10Sn-H2b/J f 66.3333 5.241 76.6442 56.0225
NOD.B10Sn-H2b/J m 39.0 5.9428 50.6914 27.3086
NON/ShiLtJ f 31.0 5.559 41.9363 20.0637
NON/ShiLtJ m 34.125 5.559 45.0613 23.1887
NZO/HlLtJ f 54.5 5.559 65.4363 43.5637
NZO/HlLtJ m 54.1667 6.4189 66.7949 41.5385
P/J f 90.5 5.559 101.4363 79.5637
P/J m 51.75 5.559 62.6863 40.8137
PL/J f 128.8 4.9721 138.5818 119.0182
PL/J m 127.3333 5.241 137.6442 117.0225
PWD/PhJ f 154.0 5.559 164.9363 143.0637
PWD/PhJ m 189.8571 5.9428 201.5486 178.1657
RIIIS/J f 80.2857 5.9428 91.9772 68.5943
RIIIS/J m 96.5 5.559 107.4363 85.5637
SM/J f 97.25 5.559 108.1863 86.3137
SM/J m 69.0 5.9428 80.6914 57.3086
WSB/EiJ f 109.75 5.559 120.6863 98.8137
WSB/EiJ m 73.5 6.4189 86.1282 60.8718


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ both 67.825 4.4818 76.6422 59.0078
A/J both 78.5 3.4042 85.1971 71.8029
BALB/cByJ both 83.3125 3.9308 91.0457 75.5793
BTBR T+ Itpr3tf/J both 46.375 4.8142 55.8462 36.9038
BUB/BnJ both 83.0 4.5389 91.9295 74.0705
C3H/HeJ both 75.5268 4.0687 83.5314 67.5222
C57BL/10J both 116.6875 3.9308 124.4207 108.9543
C57BL/6J both 81.6875 4.8142 91.1587 72.2163
C57BLKS/J both 78.25 3.9308 85.9832 70.5168
C57L/J both 44.8125 3.9308 52.5457 37.0793
DBA/2J both 98.9062 3.4042 105.6034 92.2091
FVB/NJ both 66.7262 3.3588 73.3341 60.1183
LP/J both 62.5625 3.9308 70.2957 54.8293
MOLF/EiJ both 154.0714 4.2022 162.3385 145.8043
NOD.B10Sn-H2b/J both 52.6667 3.9619 60.461 44.8724
NON/ShiLtJ both 32.5625 3.9308 40.2957 24.8293
NZO/HlLtJ both 54.3333 4.2457 62.6861 45.9806
P/J both 71.125 3.9308 78.8582 63.3918
PL/J both 128.0667 3.6121 135.173 120.9604
PWD/PhJ both 171.9286 4.0687 179.9332 163.924
RIIIS/J both 88.3929 4.0687 96.3974 80.3883
SM/J both 83.125 4.0687 91.1296 75.1204
WSB/EiJ both 91.625 4.2457 99.9778 83.2722




  GWAS USING LINEAR MIXED MODELS