Project measure / variable:   Petkova1   CD8_mem_effector_M12

ID, description, units MPD:24267   CD8_mem_effector_M12   CD8 T cells, effector memory, as percentage of total CD8 T cells   [%]  at age 12mo  
Data set, strains Petkova1   inbred   31 strains     sex: both     age: 52wks
Procedure immune cell quantification
Ontology mappings

  STRAIN COMPARISON PLOT
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Petkova1 - CD8 T cells, effector memory, as percentage of total CD8 T cells at age 12mo



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested30 strains30 strains
Mean of the strain means13.1   % 9.24   %
Median of the strain means9.57   % 8.30   %
SD of the strain means± 10.6 ± 5.83
Coefficient of variation (CV)0.808 0.631
Min–max range of strain means1.71   –   39.0   % 1.53   –   25.4   %
Mean sample size per strain7.6   mice 7.7   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 1698.0844 1698.0844 37.242 < 0.0001
strain 28 23423.5595 836.5557 18.3471 < 0.0001
sex:strain 28 9398.2685 335.6524 7.3614 < 0.0001
Residuals 389 17736.8372 45.596


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 3.33 2.24   8 0.793 0.674 1.78, 8.49 -0.92
129S1/SvImJ m 11.6 3.89   8 1.38 0.336 5.75, 17.7 0.4
A/J f 27.0 18.4   8 6.51 0.683 11.1, 65.6 1.32
A/J m 14.2 8.63   8 3.05 0.61 5.13, 30.2 0.85
AKR/J m 9.06 3.79   5 1.69 0.418 5.59, 14.6 -0.03
BALB/cByJ f 20.4 6.56   8 2.32 0.322 14.3, 34.1 0.69
BALB/cByJ m 6.88 5.76   8 2.04 0.837 3.08, 20.4 -0.41
BTBR T+ Itpr3tf/J f 6.42 1.82   8 0.645 0.284 4.28, 9.4 -0.63
BTBR T+ Itpr3tf/J m 6.67 1.23   7 0.465 0.185 4.74, 8.31 -0.44
BUB/BnJ f 6.69 1.61   6 0.657 0.24 4.7, 8.63 -0.6
BUB/BnJ m 6.37 3.44   9 1.15 0.539 2.27, 10.8 -0.49
C3H/HeJ f 12.7 4.47   8 1.58 0.352 7.32, 18.9 -0.03
C3H/HeJ m 11.3 3.0   8 1.06 0.265 9.21, 18.5 0.35
C57BL/10J f 39.0 17.0   8 6.0 0.435 19.7, 64.6 2.45
C57BL/10J m 12.8 7.46   7 2.82 0.581 3.77, 28.0 0.61
C57BL/6J f 33.4 16.2   8 5.73 0.484 11.0, 63.0 1.92
C57BL/6J m 11.1 2.56   8 0.906 0.232 7.55, 15.0 0.32
C57BLKS/J f 7.46 2.75   8 0.971 0.368 4.1, 10.7 -0.53
C57BLKS/J m 5.05 2.35   8 0.83 0.465 1.75, 8.58 -0.72
C57BR/cdJ f 5.98 1.44   8 0.511 0.242 3.58, 8.53 -0.67
C57BR/cdJ m 8.7 2.3   8 0.813 0.264 4.5, 11.6 -0.09
C57L/J f 6.85 3.25   7 1.23 0.474 3.79, 12.1 -0.59
C57L/J m 6.12 0.852   8 0.301 0.139 5.31, 8.04 -0.54
CAST/EiJ f 8.38 2.02   3 1.16 0.241 6.1, 9.92 -0.44
CBA/J f 2.61 1.74   8 0.617 0.668 1.69, 6.88 -0.99
CBA/J m 2.62 0.269   8 0.0952 0.103 2.14, 2.98 -1.14
DBA/2J f 18.9 10.3   6 4.21 0.546 5.86, 32.3 0.55
DBA/2J m 11.1 4.89   7 1.85 0.443 5.29, 17.7 0.32
FVB/NJ f 13.0 7.18   8 2.54 0.554 3.46, 26.0 -0.01
FVB/NJ m 15.2 8.98   8 3.18 0.59 6.47, 30.9 1.02
KK/HlJ f 9.71 2.27   8 0.803 0.234 5.93, 12.7 -0.32
KK/HlJ m 11.9 3.72   8 1.31 0.312 7.2, 17.8 0.46
LP/J f 17.1 16.9   7 6.4 0.988 4.94, 49.9 0.38
LP/J m 25.4 12.9   8 4.57 0.51 9.43, 44.8 2.77
MOLF/EiJ f 34.1 4.97   7 1.88 0.146 26.4, 41.9 1.99
MOLF/EiJ m 23.0 13.0   9 4.33 0.564 9.49, 42.6 2.36
MRL/MpJ f 28.0 12.8   8 4.54 0.458 8.41, 47.4 1.41
MRL/MpJ m 2.54 1.36   8 0.48 0.534 0.93, 5.17 -1.15
NON/ShiLtJ f 12.4 2.64   8 0.933 0.213 9.47, 17.0 -0.06
NON/ShiLtJ m 14.5 3.44   6 1.4 0.237 11.6, 21.2 0.9
NZO/HlLtJ f 14.9 6.37   7 2.41 0.429 7.23, 22.8 0.17
NZO/HlLtJ m 5.27 0.87   7 0.329 0.165 3.86, 6.24 -0.68
NZW/LacJ f 1.71 0.937   8 0.331 0.548 0.87, 3.79 -1.07
NZW/LacJ m 2.97 0.968   8 0.342 0.326 2.07, 4.97 -1.08
P/J f 9.42 6.36   8 2.25 0.674 4.96, 23.0 -0.35
P/J m 15.9 3.18   7 1.2 0.2 11.9, 20.2 1.14
PL/J f 2.46 1.35   7 0.511 0.551 1.57, 5.47 -1.0
PL/J m 3.12 0.854   6 0.349 0.274 1.94, 4.22 -1.05
PWD/PhJ f 2.12 0.715   8 0.253 0.337 0.97, 2.96 -1.04
PWD/PhJ m 1.93 0.814   8 0.288 0.421 1.07, 3.61 -1.25
RIIIS/J f 6.02 2.76   8 0.976 0.459 3.18, 11.9 -0.67
RIIIS/J m 7.87 2.32   8 0.821 0.295 5.69, 12.5 -0.24
SJL/J f 21.8 10.1   8 3.59 0.465 7.85, 38.4 0.83
SJL/J m 9.91 5.55   9 1.85 0.56 4.36, 20.3 0.11
SM/J f 2.41 1.22   8 0.431 0.505 1.26, 5.13 -1.01
SM/J m 4.75 4.61   8 1.63 0.972 1.84, 15.6 -0.77
SWR/J f 15.6 3.48   7 1.31 0.223 11.9, 20.7 0.24
SWR/J m 7.9 2.27   7 0.856 0.287 3.71, 10.9 -0.23
WSB/EiJ f 2.12 1.4   8 0.495 0.659 0.69, 3.96 -1.04
WSB/EiJ m 1.53 0.677   8 0.239 0.442 0.69, 2.68 -1.32


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f 3.33 2.3874 8.0237 0.0
129S1/SvImJ m 11.5762 2.3874 16.27 6.8825
A/J f 26.975 2.3874 31.6687 22.2813
A/J m 14.1538 2.3874 18.8475 9.46
BALB/cByJ f 20.4 2.3874 25.0937 15.7063
BALB/cByJ m 6.8825 2.3874 11.5762 2.1888
BTBR T+ Itpr3tf/J f 6.4212 2.3874 11.115 1.7275
BTBR T+ Itpr3tf/J m 6.6686 2.5522 11.6864 1.6507
BUB/BnJ f 6.6933 2.7567 12.1132 1.2735
BUB/BnJ m 6.3744 2.2508 10.7998 1.9491
C3H/HeJ f 12.715 2.3874 17.4087 8.0213
C3H/HeJ m 11.3063 2.3874 16.0 6.6125
C57BL/10J f 38.975 2.3874 43.6687 34.2813
C57BL/10J m 12.8443 2.5522 17.8621 7.8265
C57BL/6J f 33.4375 2.3874 38.1312 28.7438
C57BL/6J m 11.06 2.3874 15.7537 6.3663
C57BLKS/J f 7.4562 2.3874 12.15 2.7625
C57BLKS/J m 5.0512 2.3874 9.745 0.3575
C57BR/cdJ f 5.9763 2.3874 10.67 1.2825
C57BR/cdJ m 8.7025 2.3874 13.3962 4.0088
C57L/J f 6.8529 2.5522 11.8707 1.835
C57L/J m 6.1238 2.3874 10.8175 1.43
CBA/J f 2.6112 2.3874 7.305 0.0
CBA/J m 2.6237 2.3874 7.3175 0.0
DBA/2J f 18.8933 2.7567 24.3132 13.4735
DBA/2J m 11.0543 2.5522 16.0721 6.0365
FVB/NJ f 12.965 2.3874 17.6587 8.2713
FVB/NJ m 15.2275 2.3874 19.9212 10.5338
KK/HlJ f 9.7112 2.3874 14.405 5.0175
KK/HlJ m 11.9313 2.3874 16.625 7.2375
LP/J f 17.1471 2.5522 22.165 12.1293
LP/J m 25.3537 2.3874 30.0475 20.66
MOLF/EiJ f 34.1429 2.5522 39.1607 29.125
MOLF/EiJ m 23.01 2.2508 27.4353 18.5847
MRL/MpJ f 28.0263 2.3874 32.72 23.3325
MRL/MpJ m 2.5437 2.3874 7.2375 0.0
NON/ShiLtJ f 12.41 2.3874 17.1037 7.7163
NON/ShiLtJ m 14.5333 2.7567 19.9532 9.1135
NZO/HlLtJ f 14.8543 2.5522 19.8721 9.8365
NZO/HlLtJ m 5.2657 2.5522 10.2835 0.2479
NZW/LacJ f 1.7113 2.3874 6.405 0.0
NZW/LacJ m 2.9713 2.3874 7.665 0.0
P/J f 9.4238 2.3874 14.1175 4.73
P/J m 15.9143 2.5522 20.9321 10.8965
PL/J f 2.4571 2.5522 7.475 0.0
PL/J m 3.12 2.7567 8.5399 0.0
PWD/PhJ f 2.12 2.3874 6.8137 0.0
PWD/PhJ m 1.9325 2.3874 6.6262 0.0
RIIIS/J f 6.0163 2.3874 10.71 1.3225
RIIIS/J m 7.8675 2.3874 12.5612 3.1738
SJL/J f 21.8312 2.3874 26.525 17.1375
SJL/J m 9.91 2.2508 14.3353 5.4847
SM/J f 2.4138 2.3874 7.1075 0.0
SM/J m 4.745 2.3874 9.4387 0.0513
SWR/J f 15.6 2.5522 20.6178 10.5822
SWR/J m 7.9 2.5522 12.9178 2.8822
WSB/EiJ f 2.1238 2.3874 6.8175 0.0
WSB/EiJ m 1.53 2.3874 6.2237 0.0


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ both 7.4531 1.6881 10.7721 4.1341
A/J both 20.5644 1.6881 23.8834 17.2454
BALB/cByJ both 13.6412 1.6881 16.9602 10.3223
BTBR T+ Itpr3tf/J both 6.5449 1.7474 9.9804 3.1094
BUB/BnJ both 6.5339 1.7794 10.0324 3.0354
C3H/HeJ both 12.0106 1.6881 15.3296 8.6916
C57BL/10J both 25.9096 1.7474 29.3451 22.4742
C57BL/6J both 22.2488 1.6881 25.5677 18.9298
C57BLKS/J both 6.2537 1.6881 9.5727 2.9348
C57BR/cdJ both 7.3394 1.6881 10.6584 4.0204
C57L/J both 6.4883 1.7474 9.9238 3.0528
CBA/J both 2.6175 1.6881 5.9365 0.0
DBA/2J both 14.9738 1.8784 18.6668 11.2808
FVB/NJ both 14.0963 1.6881 17.4152 10.7773
KK/HlJ both 10.8213 1.6881 14.1402 7.5023
LP/J both 21.2504 1.7474 24.6859 17.815
MOLF/EiJ both 28.5764 1.7015 31.9216 25.2312
MRL/MpJ both 15.285 1.6881 18.604 11.966
NON/ShiLtJ both 13.4717 1.8234 17.0566 9.8868
NZO/HlLtJ both 10.06 1.8047 13.6081 6.5119
NZW/LacJ both 2.3413 1.6881 5.6602 0.0
P/J both 12.669 1.7474 16.1045 9.2335
PL/J both 2.7886 1.8784 6.4816 0.0
PWD/PhJ both 2.0263 1.6881 5.3452 0.0
RIIIS/J both 6.9419 1.6881 10.2609 3.6229
SJL/J both 15.8706 1.6406 19.0961 12.6452
SM/J both 3.5794 1.6881 6.8984 0.2604
SWR/J both 11.75 1.8047 15.2981 8.2019
WSB/EiJ both 1.8269 1.6881 5.1459 0.0




  GWAS USING LINEAR MIXED MODELS