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Project measure / variable:   Petkova1   CD4_effector_M12

ID, description, units MPD:24247   CD4_effector_M12   CD4 T cells, effector, as percentage of total CD4 T cells   [%]  at age 12mo  
Data set, strains Petkova1   inbred   31 strains     sex: both     age: 52wks
Procedure immune cell quantification
Ontology mappings

  STRAIN COMPARISON PLOT
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Petkova1 - CD4 T cells, effector, as percentage of total CD4 T cells at age 12mo



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested30 strains30 strains
Mean of the strain means22.7   % 24.5   %
Median of the strain means16.1   % 17.6   %
SD of the strain means± 15.6 ± 18.0
Coefficient of variation (CV)0.689 0.737
Min–max range of strain means4.49   –   56.4   % 8.44   –   77.3   %
Mean sample size per strain7.6   mice 7.7   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 508.7677 508.7677 7.9462 0.0051
strain 28 101887.2934 3638.8319 56.8332 < 0.0001
sex:strain 28 29942.1797 1069.3636 16.7019 < 0.0001
Residuals 389 24906.3217 64.0265


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 14.1 2.63   8 0.931 0.187 11.4, 19.9 -0.55
129S1/SvImJ m 74.7 4.8   8 1.7 0.0642 65.9, 79.8 2.79
A/J f 13.5 2.77   8 0.981 0.206 9.63, 18.6 -0.59
A/J m 14.0 2.96   8 1.05 0.212 10.6, 18.8 -0.58
AKR/J m 20.4 16.6   5 7.42 0.812 10.8, 50.0 -0.23
BALB/cByJ f 35.5 7.14   8 2.53 0.201 25.9, 45.1 0.82
BALB/cByJ m 39.2 24.4   8 8.62 0.623 16.4, 76.0 0.82
BTBR T+ Itpr3tf/J f 12.8 1.7   8 0.6 0.133 11.0, 16.3 -0.63
BTBR T+ Itpr3tf/J m 13.4 2.06   7 0.779 0.154 10.8, 17.3 -0.61
BUB/BnJ f 14.4 6.26   6 2.55 0.436 7.54, 25.0 -0.53
BUB/BnJ m 15.7 10.4   9 3.48 0.664 7.36, 41.8 -0.49
C3H/HeJ f 56.4 9.91   8 3.5 0.176 43.0, 71.4 2.16
C3H/HeJ m 45.9 6.74   8 2.38 0.147 37.1, 55.2 1.19
C57BL/10J f 36.9 14.5   8 5.13 0.394 16.9, 59.6 0.91
C57BL/10J m 18.2 2.75   7 1.04 0.151 14.8, 22.4 -0.35
C57BL/6J f 49.2 13.0   8 4.6 0.264 26.5, 67.9 1.7
C57BL/6J m 45.1 7.98   8 2.82 0.177 33.9, 56.5 1.14
C57BLKS/J f 12.2 1.96   8 0.694 0.16 8.68, 14.7 -0.67
C57BLKS/J m 13.3 1.31   8 0.462 0.0978 11.2, 15.0 -0.62
C57BR/cdJ f 54.2 11.7   8 4.14 0.216 41.7, 77.5 2.02
C57BR/cdJ m 21.7 4.91   8 1.74 0.227 15.7, 32.3 -0.15
C57L/J f 33.0 5.49   7 2.07 0.166 25.5, 39.7 0.66
C57L/J m 41.4 7.89   8 2.79 0.19 32.9, 53.8 0.94
CAST/EiJ f 19.0 2.81   3 1.62 0.148 16.3, 21.9 -0.24
CBA/J f 17.8 22.4   8 7.91 1.26 7.46, 72.7 -0.31
CBA/J m 9.23 1.35   8 0.476 0.146 7.07, 10.7 -0.85
DBA/2J f 21.8 5.17   6 2.11 0.237 15.4, 30.0 -0.06
DBA/2J m 9.62 2.05   7 0.776 0.213 6.77, 12.8 -0.82
FVB/NJ f 8.67 1.75   8 0.617 0.201 6.78, 11.9 -0.9
FVB/NJ m 10.3 2.07   8 0.733 0.202 7.35, 14.2 -0.79
KK/HlJ f 15.9 2.25   8 0.797 0.142 12.4, 19.0 -0.43
KK/HlJ m 23.8 7.31   8 2.59 0.308 17.1, 39.5 -0.04
LP/J f 7.51 4.76   7 1.8 0.634 3.63, 15.9 -0.97
LP/J m 9.31 2.14   8 0.756 0.23 6.95, 12.6 -0.84
MOLF/EiJ f 54.6 8.35   7 3.15 0.153 39.3, 62.9 2.04
MOLF/EiJ m 77.3 13.5   9 4.51 0.175 50.5, 90.6 2.93
MRL/MpJ f 33.6 11.2   8 3.97 0.334 17.4, 51.6 0.7
MRL/MpJ m 8.44 8.88   8 3.14 1.05 3.33, 29.6 -0.89
NON/ShiLtJ f 19.2 9.3   8 3.29 0.483 11.7, 41.0 -0.22
NON/ShiLtJ m 31.6 5.83   6 2.38 0.185 22.1, 37.3 0.4
NZO/HlLtJ f 43.5 6.74   7 2.55 0.155 29.1, 48.3 1.33
NZO/HlLtJ m 35.7 17.4   7 6.57 0.486 15.6, 64.2 0.62
NZW/LacJ f 4.49 1.11   8 0.393 0.247 3.2, 6.63 -1.16
NZW/LacJ m 12.5 2.0   8 0.708 0.161 10.0, 16.3 -0.66
P/J f 8.3 2.05   8 0.725 0.247 6.41, 11.6 -0.92
P/J m 25.0 5.78   7 2.19 0.231 18.5, 35.0 0.03
PL/J f 19.7 8.5   7 3.21 0.432 13.1, 38.0 -0.19
PL/J m 23.1 2.82   6 1.15 0.122 20.6, 27.8 -0.08
PWD/PhJ f 11.2 5.04   8 1.78 0.449 6.84, 21.2 -0.73
PWD/PhJ m 30.8 10.4   8 3.68 0.338 12.0, 44.6 0.35
RIIIS/J f 12.8 3.05   8 1.08 0.239 8.98, 18.4 -0.63
RIIIS/J m 13.2 2.37   8 0.838 0.179 9.7, 17.1 -0.62
SJL/J f 16.3 4.8   8 1.7 0.293 9.89, 25.3 -0.41
SJL/J m 17.1 6.12   9 2.04 0.357 8.14, 24.7 -0.41
SM/J f 8.29 0.99   8 0.35 0.119 7.28, 10.1 -0.92
SM/J m 11.1 3.31   8 1.17 0.299 7.45, 16.2 -0.74
SWR/J f 15.1 2.59   7 0.98 0.172 11.8, 19.9 -0.48
SWR/J m 14.2 2.05   7 0.774 0.145 11.6, 17.0 -0.57
WSB/EiJ f 10.2 4.02   8 1.42 0.393 5.81, 18.6 -0.8
WSB/EiJ m 8.61 1.81   8 0.641 0.211 7.23, 12.8 -0.88


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f 14.0625 2.829 19.6246 8.5004
129S1/SvImJ m 74.7125 2.829 80.2746 69.1504
A/J f 13.4787 2.829 19.0408 7.9167
A/J m 13.9875 2.829 19.5496 8.4254
BALB/cByJ f 35.525 2.829 41.0871 29.9629
BALB/cByJ m 39.1625 2.829 44.7246 33.6004
BTBR T+ Itpr3tf/J f 12.8 2.829 18.3621 7.2379
BTBR T+ Itpr3tf/J m 13.3714 3.0243 19.3175 7.4253
BUB/BnJ f 14.3567 3.2667 20.7792 7.9341
BUB/BnJ m 15.7111 2.6672 20.9551 10.4671
C3H/HeJ f 56.35 2.829 61.9121 50.7879
C3H/HeJ m 45.8625 2.829 51.4246 40.3004
C57BL/10J f 36.8625 2.829 42.4246 31.3004
C57BL/10J m 18.2143 3.0243 24.1604 12.2682
C57BL/6J f 49.225 2.829 54.7871 43.6629
C57BL/6J m 45.15 2.829 50.7121 39.5879
C57BLKS/J f 12.2475 2.829 17.8096 6.6854
C57BLKS/J m 13.35 2.829 18.9121 7.7879
C57BR/cdJ f 54.1875 2.829 59.7496 48.6254
C57BR/cdJ m 21.6875 2.829 27.2496 16.1254
C57L/J f 33.0143 3.0243 38.9604 27.0682
C57L/J m 41.4125 2.829 46.9746 35.8504
CBA/J f 17.82 2.829 23.3821 12.2579
CBA/J m 9.2338 2.829 14.7958 3.6717
DBA/2J f 21.8333 3.2667 28.2559 15.4108
DBA/2J m 9.6229 3.0243 15.569 3.6768
FVB/NJ f 8.6713 2.829 14.2333 3.1092
FVB/NJ m 10.2675 2.829 15.8296 4.7054
KK/HlJ f 15.8875 2.829 21.4496 10.3254
KK/HlJ m 23.7625 2.829 29.3246 18.2004
LP/J f 7.5086 3.0243 13.4547 1.5625
LP/J m 9.3112 2.829 14.8733 3.7492
MOLF/EiJ f 54.5857 3.0243 60.5318 48.6396
MOLF/EiJ m 77.2667 2.6672 82.5106 72.0227
MRL/MpJ f 33.6125 2.829 39.1746 28.0504
MRL/MpJ m 8.4362 2.829 13.9983 2.8742
NON/ShiLtJ f 19.2375 2.829 24.7996 13.6754
NON/ShiLtJ m 31.5667 3.2667 37.9892 25.1441
NZO/HlLtJ f 43.5143 3.0243 49.4604 37.5682
NZO/HlLtJ m 35.7429 3.0243 41.689 29.7968
NZW/LacJ f 4.4862 2.829 10.0483 0.0
NZW/LacJ m 12.4625 2.829 18.0246 6.9004
P/J f 8.2988 2.829 13.8608 2.7367
P/J m 25.0143 3.0243 30.9604 19.0682
PL/J f 19.7 3.0243 25.6461 13.7539
PL/J m 23.1 3.2667 29.5225 16.6775
PWD/PhJ f 11.2375 2.829 16.7996 5.6754
PWD/PhJ m 30.8375 2.829 36.3996 25.2754
RIIIS/J f 12.7725 2.829 18.3346 7.2104
RIIIS/J m 13.2375 2.829 18.7996 7.6754
SJL/J f 16.3487 2.829 21.9108 10.7867
SJL/J m 17.1156 2.6672 22.3595 11.8716
SM/J f 8.2887 2.829 13.8508 2.7267
SM/J m 11.1038 2.829 16.6658 5.5417
SWR/J f 15.1 3.0243 21.0461 9.1539
SWR/J m 14.1571 3.0243 20.1032 8.211
WSB/EiJ f 10.2275 2.829 15.7896 4.6654
WSB/EiJ m 8.6075 2.829 14.1696 3.0454


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ both 44.3875 2.0004 48.3205 40.4545
A/J both 13.7331 2.0004 17.6661 9.8001
BALB/cByJ both 37.3438 2.0004 41.2767 33.4108
BTBR T+ Itpr3tf/J both 13.0857 2.0706 17.1567 9.0147
BUB/BnJ both 15.0339 2.1086 19.1796 10.8882
C3H/HeJ both 51.1062 2.0004 55.0392 47.1733
C57BL/10J both 27.5384 2.0706 31.6094 23.4674
C57BL/6J both 47.1875 2.0004 51.1205 43.2545
C57BLKS/J both 12.7987 2.0004 16.7317 8.8658
C57BR/cdJ both 37.9375 2.0004 41.8705 34.0045
C57L/J both 37.2134 2.0706 41.2844 33.1424
CBA/J both 13.5269 2.0004 17.4599 9.5939
DBA/2J both 15.7281 2.2259 20.1043 11.3519
FVB/NJ both 9.4694 2.0004 13.4024 5.5364
KK/HlJ both 19.825 2.0004 23.758 15.892
LP/J both 8.4099 2.0706 12.4809 4.3389
MOLF/EiJ both 65.9262 2.0162 69.8903 61.9621
MRL/MpJ both 21.0244 2.0004 24.9574 17.0914
NON/ShiLtJ both 25.4021 2.1607 29.6502 21.154
NZO/HlLtJ both 39.6286 2.1385 43.8331 35.424
NZW/LacJ both 8.4744 2.0004 12.4074 4.5414
P/J both 16.6565 2.0706 20.7275 12.5855
PL/J both 21.4 2.2259 25.7762 17.0238
PWD/PhJ both 21.0375 2.0004 24.9705 17.1045
RIIIS/J both 13.005 2.0004 16.938 9.072
SJL/J both 16.7322 1.9441 20.5543 12.91
SM/J both 9.6963 2.0004 13.6292 5.7633
SWR/J both 14.6286 2.1385 18.8331 10.424
WSB/EiJ both 9.4175 2.0004 13.3505 5.4845




  GWAS USING LINEAR MIXED MODELS