Project measure / variable:   Eumorphia1   CHOL

ID, description, units MPD:23921   CHOL   total cholesterol (plasma CHOL)   [mg/dL]  
Data set, strains Eumorphia1   inbred   6 strains     sex: both     age: 12wks
Procedure lipid profile
Ontology mappings

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  STRAIN COMPARISON PLOT
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Eumorphia1 - total cholesterol (plasma CHOL)



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested6 strains6 strains
Mean of the strain means103   mg/dL 117   mg/dL
Median of the strain means106   mg/dL 118   mg/dL
SD of the strain means± 12.8 ± 27.9
Coefficient of variation (CV)0.124 0.238
Min–max range of strain means84.4   –   118   mg/dL 73.3   –   150   mg/dL
Mean sample size per strain26.5   mice 26.3   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 21289.9699 21289.9699 38.0739 < 0.0001
strain 5 105792.0382 21158.4076 37.8387 < 0.0001
sex:strain 5 29295.2837 5859.0567 10.478 < 0.0001
Residuals 305 170548.2111 559.1745


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S2/SvPas f 102.0 17.9   39 2.87 0.175 30.4, 138.0 -0.07
129S2/SvPas m 119.0 12.9   34 2.21 0.108 78.8, 142.0 0.06
BALB/cAnNCrl f 118.0 21.1   6 8.62 0.18 78.8, 135.0 1.19
BALB/cAnNCrl m 102.0 18.3   7 6.93 0.18 75.3, 126.0 -0.55
BALB/cJ f 91.6 13.7   35 2.32 0.15 69.4, 115.0 -0.88
BALB/cJ m 117.0 16.7   34 2.87 0.143 94.4, 154.0 -0.01
C3HeB/FeJ f 109.0 24.2   35 4.09 0.221 81.5, 170.0 0.48
C3HeB/FeJ m 150.0 25.1   35 4.24 0.167 114.0, 193.0 1.17
C3H/HeH f 112.0 19.5   10 6.17 0.174 83.1, 146.0 0.72
C3H/HeH m 143.0 16.1   10 5.08 0.112 123.0, 182.0 0.92
C57BL/6J f 84.4 20.3   34 3.47 0.24 28.5, 122.0 -1.44
C57BL/6J m 73.3 44.2   38 7.18 0.603 19.1, 128.0 -1.58


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S2/SvPas f 102.041 3.7865 109.4921 94.59
129S2/SvPas m 119.4618 4.0554 127.4419 111.4817
BALB/cAnNCrl f 117.6333 9.6538 136.6298 98.6369
BALB/cAnNCrl m 101.6286 8.9377 119.2159 84.0413
BALB/cJ f 91.6 3.9971 99.4653 83.7347
BALB/cJ m 116.7588 4.0554 124.7389 108.7787
C3HeB/FeJ f 109.2943 3.9971 117.1596 101.429
C3HeB/FeJ m 149.6571 3.9971 157.5224 141.7919
C3H/HeH f 112.21 7.4778 126.9246 97.4954
C3H/HeH m 143.1 7.4778 157.8146 128.3854
C57BL/6J f 84.3588 4.0554 92.3389 76.3787
C57BL/6J m 73.3158 3.836 80.8642 65.7674


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S2/SvPas both 110.7514 2.7742 116.2103 105.2925
BALB/cAnNCrl both 109.631 6.578 122.5749 96.687
BALB/cJ both 104.1794 2.847 109.7818 98.5771
C3HeB/FeJ both 129.4757 2.8263 135.0373 123.9141
C3H/HeH both 127.655 5.2876 138.0598 117.2502
C57BL/6J both 78.8373 2.7911 84.3296 73.345




GWAS analysis not available: SNP data is not available for enough strains (at least 4)