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Project measure / variable:   Eumorphia1   LDL

ID, description, units MPD:23910   LDL   non-HDL cholesterol (plasma non-HDL)   [mg/dL]  
Data set, strains Eumorphia1   inbred   4 strains     sex: both     age: 12wks
Procedure lipid profile
Ontology mappings

  STRAIN COMPARISON PLOT
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Eumorphia1 - non-HDL cholesterol (plasma non-HDL)



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested4 strains4 strains
Mean of the strain means17.9   mg/dL 20.0   mg/dL
Median of the strain means19.1   mg/dL 20.4   mg/dL
SD of the strain means± 4.87 ± 3.21
Coefficient of variation (CV)0.271 0.161
Min–max range of strain means11.5   –   22.0   mg/dL 16.3   –   23.0   mg/dL
Mean sample size per strain13.8   mice 16.5   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 158.7418 158.7418 11.7181 0.0009
strain 3 1372.8609 457.6203 33.7808 < 0.0001
sex:strain 3 79.566 26.522 1.9578 0.1244
Residuals 113 1530.7839 13.5468


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S2/SvPas f 16.9 3.71   16 0.928 0.219 8.58, 24.6 -0.22
129S2/SvPas m 18.4 5.41   16 1.35 0.294 10.9, 30.8 -0.51
BALB/cJ f 21.4 4.47   15 1.15 0.209 14.4, 26.9 0.71
BALB/cJ m 23.0 2.72   17 0.659 0.118 18.3, 28.5 0.93
C3HeB/FeJ f 11.5 2.01   14 0.538 0.175 9.36, 16.0 -1.33
C3HeB/FeJ m 16.3 2.69   17 0.653 0.165 11.3, 20.7 -1.16
C57BL/6J f 22.0 1.88   10 0.595 0.0854 19.5, 25.0 0.83
C57BL/6J m 22.4 4.37   16 1.09 0.195 15.6, 32.0 0.74


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S2/SvPas f 16.9425 0.9201 18.7655 15.1195
129S2/SvPas m 18.4125 0.9201 20.2355 16.5895
BALB/cJ f 21.42 0.9503 23.3028 19.5372
BALB/cJ m 22.9706 0.8927 24.7391 21.202
C3HeB/FeJ f 11.5264 0.9837 13.4753 9.5776
C3HeB/FeJ m 16.3118 0.8927 18.0803 14.5432
C57BL/6J f 22.04 1.1639 24.3459 19.7341
C57BL/6J m 22.4 0.9201 24.223 20.577


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S2/SvPas both 17.6775 0.6506 18.9665 16.3885
BALB/cJ both 22.1953 0.6519 23.4869 20.9037
C3HeB/FeJ both 13.9191 0.6642 15.2349 12.6033
C57BL/6J both 22.22 0.7418 23.6897 20.7503




GWAS analysis not available: SNP data is not available for enough strains (at least 4)