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Project measure / variable:   Jaxpheno2   pct_spleen16

ID, description, units MPD:22743   pct_spleen16   spleen weight, as percentage of body weight   [%]  at age 16wks  
Data set, strains Jaxpheno2   inbred   9 strains     sex: both     age: 16wks
Procedure organ weights
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  STRAIN COMPARISON PLOT
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Jaxpheno2 - spleen weight, as percentage of body weight at age 16wks



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested9 strains9 strains
Mean of the strain means0.358   % 0.259   %
Median of the strain means0.370   % 0.282   %
SD of the strain means± 0.0973 ± 0.0745
Coefficient of variation (CV)0.272 0.288
Min–max range of strain means0.172   –   0.474   % 0.118   –   0.380   %
Mean sample size per strain7.0   mice 7.1   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 0.3532 0.3532 255.678 < 0.0001
strain 8 0.6267 0.0783 56.7029 < 0.0001
sex:strain 8 0.0333 0.0042 3.0157 0.004
Residuals 120 0.1658 0.0014


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
B6D2F1/J f 0.278 0.0236   4 0.0118 0.0851 0.26, 0.31 -0.82
B6D2F1/J m 0.196 0.0152   5 0.00678 0.0774 0.18, 0.22 -0.85
BALB/cByJ f 0.432 0.0418   10 0.0132 0.0969 0.39, 0.54 0.76
BALB/cByJ m 0.29 0.0149   10 0.00471 0.0514 0.26, 0.31 0.42
C3H/HeJ f 0.454 0.0195   5 0.00872 0.0429 0.43, 0.48 0.99
C3H/HeJ m 0.3 0.0265   5 0.0118 0.0882 0.26, 0.33 0.55
C57BL/6J f 0.37 0.028   15 0.00724 0.0758 0.32, 0.42 0.12
C57BL/6J m 0.262 0.0443   15 0.0114 0.169 0.21, 0.4 0.04
CBA/J f 0.29 0.0374   9 0.0125 0.129 0.24, 0.37 -0.7
CBA/J m 0.215 0.0497   10 0.0157 0.231 0.17, 0.35 -0.59
DBA/2J f 0.4 0.0255   5 0.0114 0.0637 0.37, 0.43 0.43
DBA/2J m 0.282 0.0217   5 0.0097 0.0769 0.26, 0.31 0.31
FVB/NJ f 0.474 0.0416   5 0.0186 0.0877 0.42, 0.51 1.19
FVB/NJ m 0.38 0.057   5 0.0255 0.15 0.34, 0.48 1.62
NOD.CB17-Prkdcscid/J f 0.172 0.0239   5 0.0107 0.139 0.15, 0.21 -1.91
NOD.CB17-Prkdcscid/J m 0.118 0.00837   5 0.00374 0.0709 0.11, 0.13 -1.89
NOD/ShiLtJ f 0.351 0.0624   10 0.0197 0.178 0.2, 0.41 -0.07
NOD/ShiLtJ m 0.288 0.0282   10 0.00892 0.0979 0.26, 0.34 0.39


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
B6D2F1/J f 0.2775 0.0186 0.3143 0.2407
B6D2F1/J m 0.196 0.0166 0.2289 0.1631
BALB/cByJ f 0.432 0.0118 0.4553 0.4087
BALB/cByJ m 0.29 0.0118 0.3133 0.2667
C3H/HeJ f 0.454 0.0166 0.4869 0.4211
C3H/HeJ m 0.3 0.0166 0.3329 0.2671
C57BL/6J f 0.37 0.0096 0.389 0.351
C57BL/6J m 0.262 0.0096 0.281 0.243
CBA/J f 0.29 0.0124 0.3145 0.2655
CBA/J m 0.215 0.0118 0.2383 0.1917
DBA/2J f 0.4 0.0166 0.4329 0.3671
DBA/2J m 0.282 0.0166 0.3149 0.2491
FVB/NJ f 0.474 0.0166 0.5069 0.4411
FVB/NJ m 0.38 0.0166 0.4129 0.3471
NOD.CB17-Prkdcscid/J f 0.172 0.0166 0.2049 0.1391
NOD.CB17-Prkdcscid/J m 0.118 0.0166 0.1509 0.0851
NOD/ShiLtJ f 0.351 0.0118 0.3743 0.3277
NOD/ShiLtJ m 0.288 0.0118 0.3113 0.2647


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
B6D2F1/J both 0.2367 0.0125 0.2614 0.2121
BALB/cByJ both 0.361 0.0083 0.3775 0.3445
C3H/HeJ both 0.377 0.0118 0.4003 0.3537
C57BL/6J both 0.316 0.0068 0.3294 0.3026
CBA/J both 0.2525 0.0085 0.2694 0.2356
DBA/2J both 0.341 0.0118 0.3643 0.3177
FVB/NJ both 0.427 0.0118 0.4503 0.4037
NOD.CB17-Prkdcscid/J both 0.145 0.0118 0.1683 0.1217
NOD/ShiLtJ both 0.3195 0.0083 0.336 0.303




  GWAS USING LINEAR MIXED MODELS